2WK3
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1YRU
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4LX2
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![BU of 4lx2 by Molmil](/molmil-images/mine/4lx2) | Crystal structure of Myo5a globular tail domain in complex with melanophilin GTBD | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Melanophilin, Unconventional myosin-Va | Authors: | Pylypenko, O, Attanda, W, Gauquelin, C, Houdusse, A. | Deposit date: | 2013-07-29 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
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4LX0
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![BU of 4lx0 by Molmil](/molmil-images/mine/4lx0) | Crystal structure of Myo5b globular tail domain in complex with active Rab11a | Descriptor: | BERYLLIUM TRIFLUORIDE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Pylypenko, O, Attanda, W, Gauquelin, C, Houdusse, A. | Deposit date: | 2013-07-29 | Release date: | 2013-11-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
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1ZOT
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![BU of 1zot by Molmil](/molmil-images/mine/1zot) | crystal structure analysis of the CyaA/C-Cam with PMEAPP | Descriptor: | (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE, CALCIUM ION, Calmodulin, ... | Authors: | Guo, Q, Tang, W.J. | Deposit date: | 2005-05-13 | Release date: | 2005-08-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin. Embo J., 24, 2005
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4LX1
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![BU of 4lx1 by Molmil](/molmil-images/mine/4lx1) | Crystal structure of Myo5a globular tail domain | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | Authors: | Pylypenko, O, Attanda, W, Coulibaly, D, Gauquelin, C, Houdusse, A. | Deposit date: | 2013-07-29 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
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6IXN
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![BU of 6ixn by Molmil](/molmil-images/mine/6ixn) | Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with NAD+ and citrate | Descriptor: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Zhu, G.P, Tang, W.G, Wang, P. | Deposit date: | 2018-12-11 | Release date: | 2019-12-18 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs. Arch.Biochem.Biophys., 708, 2021
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6IXT
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![BU of 6ixt by Molmil](/molmil-images/mine/6ixt) | Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with NAD+ and Mg2+ | Descriptor: | GLYCEROL, Isocitrate dehydrogenase, MAGNESIUM ION, ... | Authors: | Zhu, G.P, Tang, W.G, Wang, P. | Deposit date: | 2018-12-12 | Release date: | 2019-12-18 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs. Arch.Biochem.Biophys., 708, 2021
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4BWF
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![BU of 4bwf by Molmil](/molmil-images/mine/4bwf) | Pex4p-Pex22p disulphide bond mutant | Descriptor: | 1,2-ETHANEDIOL, PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA | Authors: | Williams, C, van den Berg, M, Stanley, W.A, Wilmanns, M, Distel, B. | Deposit date: | 2013-07-01 | Release date: | 2013-07-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | A Disulphide Bond in the E2 Enzyme Pex4P Modulates Ubiquitin-Conjugating Activity Sci.Rep., 3, 2013
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6MCK
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![BU of 6mck by Molmil](/molmil-images/mine/6mck) | p97 D1D2 with CB5083 bound | Descriptor: | 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, Transitional endoplasmic reticulum ATPase | Authors: | Xia, D, Tang, W.K. | Deposit date: | 2018-08-31 | Release date: | 2019-01-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.77 Å) | Cite: | Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083. Mol. Pharmacol., 95, 2019
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6IXL
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![BU of 6ixl by Molmil](/molmil-images/mine/6ixl) | Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri | Descriptor: | GLYCEROL, Isocitrate dehydrogenase, SULFATE ION | Authors: | Zhu, G.P, Tang, W.G, Wang, P. | Deposit date: | 2018-12-11 | Release date: | 2019-12-18 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs. Arch.Biochem.Biophys., 708, 2021
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6KY6
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![BU of 6ky6 by Molmil](/molmil-images/mine/6ky6) | Crystal structure of a thermostable aldo-keto reductase Tm1743 in complexs with inhibitor epalrestat in space group P3221cc | Descriptor: | 2,5-diketo-D-gluconic acid reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Zhang, C.Y, Min, Z.Z, Liu, X.M, Wang, C, Tang, W.R. | Deposit date: | 2019-09-16 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima. Febs Lett., 594, 2020
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1NMI
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![BU of 1nmi by Molmil](/molmil-images/mine/1nmi) | Solution structure of the imidazole complex of iso-1 cytochrome c | Descriptor: | Cytochrome c, iso-1, HEME C, ... | Authors: | Yao, Y, Tong, Y, Liu, G, Wang, J, Zheng, J, Tang, W. | Deposit date: | 2003-01-10 | Release date: | 2003-02-04 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of the imidazole complex of iso-1 cytochrome c To be Published
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1M60
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![BU of 1m60 by Molmil](/molmil-images/mine/1m60) | Solution Structure of Zinc-substituted cytochrome c | Descriptor: | ZINC SUBSTITUTED HEME C, Zinc-substituted cytochrome c | Authors: | Qian, C, Yao, Y, Tong, Y, Wang, J, Tang, W. | Deposit date: | 2002-07-11 | Release date: | 2002-08-07 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structural analysis of zinc-substituted cytochrome c. J.Biol.Inorg.Chem., 8, 2003
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6KIK
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![BU of 6kik by Molmil](/molmil-images/mine/6kik) | Crystal structure of a thermostable aldo-keto reductase Tm1743 in complex with inhibitor tolrestat | Descriptor: | Oxidoreductase, aldo/keto reductase family, TOLRESTAT | Authors: | Zhang, C.Y, Liu, X.M, Wang, C, Tang, W.R. | Deposit date: | 2019-07-18 | Release date: | 2019-09-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Tolrestat acts atypically as a competitive inhibitor of the thermostable aldo-keto reductase Tm1743 from Thermotoga maritima. Febs Lett., 594, 2020
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3TN2
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![BU of 3tn2 by Molmil](/molmil-images/mine/3tn2) | structure analysis of MIP1-beta P8A | Descriptor: | C-C motif chemokine 4, ZINC ION | Authors: | Guo, Q, Tang, W.J. | Deposit date: | 2011-09-01 | Release date: | 2012-09-05 | Last modified: | 2018-08-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J.Mol.Biol., 427, 2015
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4NXO
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![BU of 4nxo by Molmil](/molmil-images/mine/4nxo) | Crystal Structure of Insulin Degrading Enzyme in complex with BDM44768 | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Liang, W.G, Deprez, R, Deprez, B, Tang, W. | Deposit date: | 2013-12-09 | Release date: | 2015-10-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Nat Commun, 6, 2015
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1F03
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![BU of 1f03 by Molmil](/molmil-images/mine/1f03) | SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C | Descriptor: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Wu, Y.B, Lu, J, Qian, C.M, Tang, W.X, Li, E.C, Wang, J.F, Wang, Y.H, Wang, W.H, Lu, J.X, Xie, Y, Huang, Z.X. | Deposit date: | 2000-05-14 | Release date: | 2000-06-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c. Eur.J.Biochem., 268, 2001
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1F04
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![BU of 1f04 by Molmil](/molmil-images/mine/1f04) | SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C | Descriptor: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Wu, Y.B, Lu, J, Qian, C.M, Tang, W.X, Li, E.C, Wang, J.F, Wang, Y.H, Wang, W.H, Lu, J.X, Xie, Y, Huang, Z.X. | Deposit date: | 2000-05-14 | Release date: | 2000-06-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c. Eur.J.Biochem., 268, 2001
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6J11
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![BU of 6j11 by Molmil](/molmil-images/mine/6j11) | MERS-CoV spike N-terminal domain and 7D10 scFv complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-terminal domain of Spike glycoprotein, ... | Authors: | Zhou, H, Zhang, S, Zhang, S, Tang, W, Wang, X. | Deposit date: | 2018-12-27 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein. Nat Commun, 10, 2019
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2WL8
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![BU of 2wl8 by Molmil](/molmil-images/mine/2wl8) | X-ray crystal structure of Pex19p | Descriptor: | PEROXISOMAL BIOGENESIS FACTOR 19 | Authors: | Schueller, N, Holton, S.J, Stanley, W.A, Song, Y.H, Konarev, P, Roessle, M, Erdmann, R, Schliebs, W, Wilmanns, M. | Deposit date: | 2009-06-22 | Release date: | 2010-06-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The Peroxisomal Receptor Pex19P Forms a Helical Mpts Recognition Domain. Embo J., 29, 2010
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4NGE
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![BU of 4nge by Molmil](/molmil-images/mine/4nge) | Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40) | Descriptor: | ACETATE ION, Beta-amyloid protein 40, GLYCEROL, ... | Authors: | King, J.V, Liang, W.G, Tang, W.J. | Deposit date: | 2013-11-01 | Release date: | 2014-05-14 | Last modified: | 2014-07-23 | Method: | X-RAY DIFFRACTION (2.704 Å) | Cite: | Molecular basis of substrate recognition and degradation by human presequence protease. Structure, 22, 2014
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4QIA
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![BU of 4qia by Molmil](/molmil-images/mine/4qia) | Crystal structure of human insulin degrading enzyme (ide) in complex with inhibitor N-benzyl-N-(carboxymethyl)glycyl-L-histidine | Descriptor: | Insulin-degrading enzyme, N-benzyl-N-(carboxymethyl)glycyl-L-histidine, ZINC ION | Authors: | Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J. | Deposit date: | 2014-05-30 | Release date: | 2015-05-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.202 Å) | Cite: | Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme. Eur.J.Med.Chem., 90, 2015
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2YPU
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![BU of 2ypu by Molmil](/molmil-images/mine/2ypu) | human insulin degrading enzyme E111Q in complex with inhibitor compound 41367 | Descriptor: | 2-[[2-[[(2S)-3-(3H-IMIDAZOL-4-YL)-1-METHOXY-1-OXO-PROPAN-2-YL]AMINO]-2-OXO-ETHYL]-(PHENYLMETHYL)AMINO]ETHANOIC ACID, INSULIN-DEGRADING ENZYME, ZINC ION | Authors: | Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.-J. | Deposit date: | 2012-11-01 | Release date: | 2012-11-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Imidazole-Derived 2-[N-Carbamoylmethyl-Alkylamino]Acetic Acids,Substrate-Dependent Modulators of Insulin-Degrading Enzyme in Amyloid-Beta Hydrolysis Eur J Med Chem, 79C, 2014
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1FI7
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![BU of 1fi7 by Molmil](/molmil-images/mine/1fi7) | Solution structure of the imidazole complex of cytochrome C | Descriptor: | CYTOCHROME C, HEME C, IMIDAZOLE | Authors: | Banci, L, Bertini, I, Liu, G, Lu, J, Reddig, T, Tang, W, Wu, Y, Zhu, D. | Deposit date: | 2000-08-03 | Release date: | 2000-08-23 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c J.Biol.Inorg.Chem., 6, 2001
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