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PDB: 251 件

6XOU
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CryoEM structure of human presequence protease in open state
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOV
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CryoEM structure of human presequence protease in partial closed state 1
分子名称: Amyloid-beta precursor protein, Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOW
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CryoEM structure of human presequence protease in partial close state 2, induced by presequence of citrate synthase
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献CryoEM structure of human presequence protease in partial open state 2, induced by presequence of citrate synthase
To Be Published
6XOT
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CryoEM structure of human presequence protease in partial open state 2
分子名称: Presequence protease, mitochondrial
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-07-07
公開日2021-07-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XLY
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CRYOEM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ZINC METALLOPROTEASE ZMP1 IN OPEN STATE
分子名称: Probable zinc metalloprotease Zmp1, ZINC ION
著者Liang, W.G, Zhao, M, Tang, W.
登録日2020-06-29
公開日2020-12-23
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural analysis of Mycobacterium tuberculosis M13 metalloprotease Zmp1 open states.
Structure, 29, 2021
8J23
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Cryo-EM structure of FFAR2 complex in apo state
分子名称: Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Tai, L, Li, F, Sun, X, Tang, W, Wang, J.
登録日2023-04-14
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular recognition and activation mechanism of short chain fatty acid receptors FFAR2 and FFAR3
To Be Published
5DNF
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BU of 5dnf by Molmil
Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, C-C motif chemokine 5, ...
著者Liang, W.G, Tang, W.
登録日2015-09-10
公開日2016-04-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.549 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5KKZ
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Rhodobacter sphaeroides bc1 with famoxadone
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, ASCORBIC ACID, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-23
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
8DFH
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Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
分子名称: 42C3 Fab Heavy Chain, 42C3 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFG
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Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
分子名称: 42D6 Fab Heavy Chain, 42D6 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
5UOE
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Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE)
分子名称: FAB Heavy chain with engineered elbow, FAB light chain, Insulin-degrading enzyme
著者Liang, W.G, Bailey, L, Kossiakoff, T, Tang, W.J.
登録日2017-01-31
公開日2018-02-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE)
To Be Published
3CQF
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Crystal structure of anthrolysin O (ALO)
分子名称: Thiol-activated cytolysin
著者Bourdeau, R.W, Malito, E, Tang, W.J.
登録日2008-04-02
公開日2009-03-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis
J.Biol.Chem., 284, 2009
6VGT
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Solution NMR structure of enterococcal cytolysin L (CylLL") produced by Enterococcus faecalis
分子名称: cytolysin L
著者Bobeica, S.C, van der Donk, W.A, Zhu, L, Tang, W.
登録日2020-01-08
公開日2020-07-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VE9
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Solution NMR structure of enterococcal cytolysin S (CylLS") produced by Enterococcus faecalis
分子名称: enterococcal cytolysin S
著者Bobeica, S.C, van der Donk, W.A, Zhu, L, Tang, W.
登録日2019-12-30
公開日2020-07-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
6VHJ
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BU of 6vhj by Molmil
Solution NMR of Prochlorosin 1.1 produced by Prochlorococcus MIT 9313
分子名称: Prochlorosin 1.1
著者Bobeica, S.C, van der Donk, W.A, Tang, W.
登録日2020-01-09
公開日2020-07-08
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways.
Chem Sci, 11, 2020
8TWF
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BU of 8twf by Molmil
Crystal structure of tetracycline destructase Tet(56-3)
分子名称: 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Kumar, H, Tang, W.K, Tolia, N.
登録日2023-08-21
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.
Commun Biol, 7, 2024
5JCZ
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BU of 5jcz by Molmil
Rab11 bound to MyoVa-GTD
分子名称: 1,2-ETHANEDIOL, ACETATE ION, BERYLLIUM TRIFLUORIDE ION, ...
著者Pylypenko, O, Attanda, W, Gauquelin, C, Malherbes, G, Houdusse, A.
登録日2016-04-15
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.056 Å)
主引用文献Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.
Elife, 5, 2016
1NMJ
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BU of 1nmj by Molmil
The Solution Structure of Rat Ab-(1-28) and its Interaction with Zinc: Insights into the Scarity of Amyloid Deposition in Aged Rat Brain
分子名称: amyloid beta-peptide from Alzheimer's disease amyloid A4 protein homolog
著者Huang, J, Yao, Y, Tang, W.X.
登録日2003-01-10
公開日2003-01-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of rat Abeta-(1-28) and its interaction with zinc ion: insights into the scarcity of amyloid deposition in aged rat brain
J.Biol.Inorg.Chem., 9, 2004
1PK0
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BU of 1pk0 by Molmil
Crystal Structure of the EF3-CaM complexed with PMEApp
分子名称: (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE, CALCIUM ION, Calmodulin, ...
著者Shen, Y, Tang, W.J.
登録日2003-06-04
公開日2004-02-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection.
Proc.Natl.Acad.Sci.USA, 101, 2004
5HQ0
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BU of 5hq0 by Molmil
Ternary complex of human proteins CDK1, Cyclin B and CKS2, bound to an inhibitor
分子名称: Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2, G2/mitotic-specific cyclin-B1, ...
著者Noble, M.E, Martin, M.P, Korolchuk, S, Brown, N.R, Moukhametzianov, R, Stanley, W.A.
登録日2016-01-21
公開日2016-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.
Nat Commun, 6, 2015
7VRT
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BU of 7vrt by Molmil
The unexpanded head structure of phage T4
分子名称: Capsid vertex protein, Major capsid protein
著者Fang, Q, Tang, W, Fokine, A, Mahalingam, M, Shao, Q, Rossmann, M.G, Rao, V.B.
登録日2021-10-24
公開日2022-10-05
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VS5
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BU of 7vs5 by Molmil
The expanded head structure of phage T4
分子名称: Capsid vertex protein, Major capsid protein, Small outer capsid protein
著者Fang, Q, Tang, W, Fokine, A, Mahalingam, M, Shao, Q, Rossmann, M.G, Rao, V.B.
登録日2021-10-25
公開日2022-10-05
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly.
Proc.Natl.Acad.Sci.USA, 119, 2022
8TWG
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Crystal structure of tetracycline destructase Tet(56-2)
分子名称: 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Kumar, H, Tang, W.K, Tolia, N.
登録日2023-08-21
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.
Commun Biol, 7, 2024
5WOB
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BU of 5wob by Molmil
Crystal Structure Analysis of Fab1-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin
分子名称: IDE-bound Fab heavy chain, IDE-bound Fab light chain, Insulin, ...
著者McCord, L.A, Liang, W.G, Farcasanu, M, Wang, A.G, Koide, S, Tang, W.J.
登録日2017-08-01
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
3E4A
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Human IDE-inhibitor complex at 2.6 angstrom resolution
分子名称: 1,4-DIETHYLENE DIOXIDE, ACETIC ACID, HYDROXAMATE PEPTIDE II1, ...
著者Malito, E, Leissring, M.A, Choi, S, Cuny, G.D, Tang, W.J.
登録日2008-08-11
公開日2009-05-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.
Plos One, 5, 2010

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