5HQ0

Ternary complex of human proteins CDK1, Cyclin B and CKS2, bound to an inhibitor

Summary for 5HQ0

Entry DOI	10.2210/pdb5hq0/pdb
Descriptor	Cyclin-dependent kinase 1, G2/mitotic-specific cyclin-B1, Cyclin-dependent kinases regulatory subunit 2, ... (5 entities in total)
Functional Keywords	cdk1, cyclin b, cks2, cell-cycle, protein kinase, inhibitor, transferase
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus: P06493 Cytoplasm: P14635
Total number of polymer chains	3
Total formula weight	76574.67
Authors	Noble, M.E.,Martin, M.P.,Korolchuk, S.,Brown, N.R.,Moukhametzianov, R.,Stanley, W.A. (deposition date: 2016-01-21, release date: 2016-03-02)
Primary citation	Brown, N.R.,Korolchuk, S.,Martin, M.P.,Stanley, W.A.,Moukhametzianov, R.,Noble, M.E.,Endicott, J.A. CDK1 structures reveal conserved and unique features of the essential cell cycle CDK. Nat Commun, 6:6769-, 2015 Cited by PubMed: 25864384 DOI: 10.1038/ncomms7769 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation