5HQ0
Ternary complex of human proteins CDK1, Cyclin B and CKS2, bound to an inhibitor
Summary for 5HQ0
Entry DOI | 10.2210/pdb5hq0/pdb |
Descriptor | Cyclin-dependent kinase 1, G2/mitotic-specific cyclin-B1, Cyclin-dependent kinases regulatory subunit 2, ... (5 entities in total) |
Functional Keywords | cdk1, cyclin b, cks2, cell-cycle, protein kinase, inhibitor, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P06493 Cytoplasm: P14635 |
Total number of polymer chains | 3 |
Total formula weight | 76574.67 |
Authors | Noble, M.E.,Martin, M.P.,Korolchuk, S.,Brown, N.R.,Moukhametzianov, R.,Stanley, W.A. (deposition date: 2016-01-21, release date: 2016-03-02, Last modification date: 2024-05-08) |
Primary citation | Brown, N.R.,Korolchuk, S.,Martin, M.P.,Stanley, W.A.,Moukhametzianov, R.,Noble, M.E.,Endicott, J.A. CDK1 structures reveal conserved and unique features of the essential cell cycle CDK. Nat Commun, 6:6769-, 2015 Cited by PubMed: 25864384DOI: 10.1038/ncomms7769 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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