7XOE
 
 | | Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Prefusion state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,peptide | | Authors: | Wu, Z, Yu, Z, Tan, S, Lu, J, Lu, G, Lin, J. | | Deposit date: | 2022-05-01 | | Release date: | 2024-02-14 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Sci Bull (Beijing), 68, 2023
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7XOG
 | | Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Postfusion state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,peptide, ... | | Authors: | Wu, Z, Yu, Z, Tan, S, Lu, J, Lu, G, Lin, J. | | Deposit date: | 2022-05-01 | | Release date: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Sci Bull (Beijing), 68, 2023
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4HX1
 | | Structure of HLA-A68 complexed with a tumor antigen derived peptide | | Descriptor: | 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-09 | | Release date: | 2013-10-02 | | Method: | X-RAY DIFFRACTION (1.802 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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4I48
 | | Structure of HLA-A68 complexed with an HIV Env derived peptide | | Descriptor: | 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-27 | | Release date: | 2013-10-02 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.799 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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4HWZ
 | | Structure of HLA-A68 complexed with an HIV derived peptide | | Descriptor: | 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-09 | | Release date: | 2013-10-16 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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6KSM
 | | Staphylococcus aureus lipase -Orlistat complex | | Descriptor: | (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, CALCIUM ION, LAURIC ACID, ... | | Authors: | Kitadokoro, K, Tanaka, M, Kamitani, S. | | Deposit date: | 2019-08-24 | | Release date: | 2020-04-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat.
Sci Rep, 10, 2020
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6KSI
 | | Staphylococcus aureus lipase - native | | Descriptor: | CALCIUM ION, HEXANOIC ACID, LAURIC ACID, ... | | Authors: | Kitadokoro, K, Tanaka, M, Kamitani, S. | | Deposit date: | 2019-08-24 | | Release date: | 2020-04-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Crystal structure of pathogenic Staphylococcus aureus lipase complex with the anti-obesity drug orlistat.
Sci Rep, 10, 2020
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6L06
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6L07
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1SRS
 | | SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA | | Descriptor: | DNA (5'-D(*CP*CP*(5IU)P*TP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*CP*AP*TP*GP*GP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*A P*AP*G)-3'), PROTEIN (SERUM RESPONSE FACTOR (SRF)) | | Authors: | Pellegrini, L, Tan, S, Richmond, T.J. | | Deposit date: | 1995-07-28 | | Release date: | 1995-07-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of serum response factor core bound to DNA.
Nature, 376, 1995
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2K8O
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7C88
 | | Complex structure of JS003 and PD-L1 | | Descriptor: | JS003 Heavy chain, JS003 Light chain, Programmed cell death 1 ligand 1 | | Authors: | Bi, X, Shi, R, Chai, Y, Qi, J, Yan, J, Tan, S. | | Deposit date: | 2020-05-29 | | Release date: | 2021-04-14 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | Identification of a hotspot on PD-L1 for pH-dependent binding by monoclonal antibodies for tumor therapy.
Signal Transduct Target Ther, 5, 2020
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7E57
 | | Crystal structure of murine GITR-GITRL complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18, ... | | Authors: | Zhao, M, Tan, S, Fu, L, Chai, Y, Qi, J, Gao, G.F. | | Deposit date: | 2021-02-18 | | Release date: | 2021-09-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.302 Å) | | Cite: | Atypical TNF-TNFR superfamily binding interface in the GITR-GITRL complex for T cell activation.
Cell Rep, 36, 2021
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8Y11
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8Y4J
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8XWK
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8Y4B
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8Y46
 | | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-KDF or L-2,4-DKDF | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, L-2,4-diketo-3-deoxyfuconate, ... | | Authors: | Akagashi, M, Watanabe, S. | | Deposit date: | 2024-01-30 | | Release date: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a alpha-furanosyl hemiketal of substrates.
Sci Rep, 14, 2024
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2DWV
 | | Solution structure of the second WW domain from mouse salvador homolog 1 protein (mWW45) | | Descriptor: | Salvador homolog 1 protein | | Authors: | Ohnishi, S, Kigawa, T, Koshiba, S, Tomizawa, T, Sato, M, Tochio, N, Inoue, M, Harada, T, Watanabe, S, Guntert, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-08-17 | | Release date: | 2007-02-17 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of an atypical WW domain in a novel beta-clam-like dimeric form
Febs Lett., 581, 2007
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7E5M
 | | crystal structure of trans assembled human TROP-2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor-associated calcium signal transducer 2 | | Authors: | Sun, M, Zhang, H, Chai, Y, Qi, J, Gao, G.F, Tan, S. | | Deposit date: | 2021-02-19 | | Release date: | 2021-12-15 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2.
Iscience, 24, 2021
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7E5N
 | | crystal structure of cis assembled TROP-2 | | Descriptor: | Tumor-associated calcium signal transducer 2 | | Authors: | Sun, M, Zhang, H, Chai, Y, Qi, J, Gao, G.F, Tan, S. | | Deposit date: | 2021-02-19 | | Release date: | 2021-12-15 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2.
Iscience, 24, 2021
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2DJ4
 | | Solution structure of the 13th filamin domain from human Filamin-B | | Descriptor: | Filamin-B | | Authors: | Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-03-31 | | Release date: | 2006-10-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 13th filamin domain from human Filamin-B
To be Published
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2DHZ
 | | Solution Structure of the RA Domain in the Human Link Guanine Nucleotide Exchange Factor II (Link-GEFII) | | Descriptor: | Rap guanine nucleotide exchange factor (GEF)-like 1 | | Authors: | Zhao, C, Kigawa, T, Yoneyama, M, Koshiba, S, Harada, T, Watanabe, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-03-27 | | Release date: | 2006-09-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the RA Domain in the Human Link Guanine Nucleotide Exchange Factor II (Link-GEFII)
To be Published
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2DS4
 | | Solution structure of the filamin domain from human tripartite motif protein 45 | | Descriptor: | Tripartite motif protein 45 | | Authors: | Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-06-21 | | Release date: | 2006-12-21 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the filamin domain from human tripartite motif protein 45
To be Published
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2DIC
 | | Solution structure of the 12th filamin domain from human Filamin-B | | Descriptor: | Filamin-B | | Authors: | Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-03-29 | | Release date: | 2006-09-29 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 12th filamin domain from human Filamin-B
To be Published
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