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PDB: 369 件

2C2Y
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Three Dimensional Structure of bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase from Mycobacterium tuberculosis
分子名称: METHYLENETETRAHYDROFOLATE DEHYDROGENASE-METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE
著者Javid-Majd, F, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2005-09-30
公開日2005-10-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three Dimensional Structure of Bifunctional Methylenetetrahydrofolate Dehydrogenase-Cyclohydrolase from Mycobacterium tuberculosis
To be Published
5BYT
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PRPP complexed with a single Mg in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-11
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
1U5H
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Structure of Citrate Lyase beta subunit from Mycobacterium tuberculosis
分子名称: FORMIC ACID, citE
著者Goulding, C.W, Lekin, T, Kim, C.Y, Segelke, B, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2004-07-27
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function.
J.Mol.Biol., 365, 2007
2C2X
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Three dimensional structure of bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase from Mycobacterium tuberculosis
分子名称: METHYLENETETRAHYDROFOLATE DEHYDROGENASE-METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE
著者Javid-Majd, F, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2005-09-30
公開日2005-10-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three Dimensional Structure of Bifunctional Methylenetetrahydrofolate Dehydrogenase- Cyclohydrolase from Mycobacterium tuberculosis
To be Published
2HYX
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Structure of the C-terminal domain of DipZ from Mycobacterium tuberculosis
分子名称: Protein dipZ
著者Goldstone, D, Baker, E.N, Metcalf, P, TB Structural Genomics Consortium (TBSGC)
登録日2006-08-08
公開日2007-07-17
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the C-terminal domain of DipZ from Mycobacterium tuberculosis
To be Published
2A7Y
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Solution Structure of the Conserved Hypothetical Protein Rv2302 from the Bacterium Mycobacterium tuberculosis
分子名称: Hypothetical protein Rv2302/MT2359
著者Buchko, G.W, Kim, C.-Y, Terwilliger, T.C, Kennedy, M.A, TB Structural Genomics Consortium (TBSGC)
登録日2005-07-06
公開日2005-08-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the conserved hypothetical protein Rv2302 from Mycobacterium tuberculosis.
J.Bacteriol., 188, 2006
2G2D
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Crystal structure of a putative pduO-type ATP:cobalamin adenosyltransferase from Mycobacterium tuberculosis
分子名称: ATP:cobalamin adenosyltransferase
著者Moon, J.H, Kaviratne, A, Yu, M, Bursey, E.H, Hung, L.-W, Lekin, T.P, Segelke, B.W, Terwilliger, T.C, Kim, C.-Y, TB Structural Genomics Consortium (TBSGC)
登録日2006-02-15
公開日2006-03-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a putative pduO-type ATP:cobalamin adenosyltransferase from Mycobacterium tuberculosis.
To be Published
1UE7
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Crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosis
分子名称: Single-strand binding protein
著者Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, Vijayan, M, TB Structural Genomics Consortium (TBSGC)
登録日2003-05-09
公開日2004-02-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications
J.MOL.BIOL., 331, 2003
1UE5
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Crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosis
分子名称: CADMIUM ION, Single-strand binding protein
著者Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, Vijayan, M, TB Structural Genomics Consortium (TBSGC)
登録日2003-05-09
公開日2004-02-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications
J.MOL.BIOL., 331, 2003
1UE6
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Crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosis
分子名称: Single-strand binding protein
著者Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, Vijayan, M, TB Structural Genomics Consortium (TBSGC)
登録日2003-05-09
公開日2004-02-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications
J.MOL.BIOL., 331, 2003
1SFR
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Crystal Structure of the Mycobacterium tuberculosis Antigen 85A Protein
分子名称: Antigen 85-A
著者Ronning, D.R, Vissa, V, Besra, G.S, Belisle, J.T, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2004-02-20
公開日2004-07-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mycobacterium tuberculosis Antigen 85A and 85C Structures Confirm Binding Orientation and Conserved Substrate Specificity
J.Biol.Chem., 279, 2004
2O0T
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The three dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation
分子名称: Diaminopimelate decarboxylase, SULFATE ION
著者Weyand, S, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2006-11-28
公開日2007-02-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献The three-dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation.
J Struct Funct Genomics, 10, 2009
3N8K
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Type II dehydroquinase from Mycobacterium tuberculosis complexed with citrazinic acid
分子名称: 2,6-dioxo-1,2,3,6-tetrahydropyridine-4-carboxylic acid, 3-dehydroquinate dehydratase, CHLORIDE ION
著者Snee, W.C, Palaninathan, S.K, Sacchettini, J.C, Dias, M.V.B, Bromfield, K.M, Payne, R, Ciulli, A, Howard, N.I, Abell, C, Blundell, T.L, TB Structural Genomics Consortium (TBSGC)
登録日2010-05-28
公開日2010-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis.
Biochem.J., 436, 2011
2B70
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T4 Lysozyme mutant L99A at ambient pressure
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
著者Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M, TB Structural Genomics Consortium (TBSGC)
登録日2005-10-03
公開日2005-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation
Proc.Natl.Acad.Sci.Usa, 102, 2005
5C2L
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Magnesium soaked into the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: Anthranilate phosphoribosyltransferase, IMIDAZOLE, MAGNESIUM ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-16
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.009 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
1UE1
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Crystal structure of the single-stranded dna-binding protein from mycobacterium tuberculosis
分子名称: Single-strand binding protein, ZINC ION
著者Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, Vijayan, M, TB Structural Genomics Consortium (TBSGC)
登録日2003-05-08
公開日2004-02-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Mycobacterium tuberculosis single-stranded DNA-binding protein. Variability in quaternary structure and its implications
J.MOL.BIOL., 331, 2003
5C7S
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PRPP complexed with two Mn2+ in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MANGANESE (II) ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-24
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
3N59
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Type II dehydroquinase from Mycobacterium Tuberculosis complexed with 3-dehydroshikimate
分子名称: (4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acid, 3-dehydroquinate dehydratase, CHLORIDE ION
著者Snee, W.C, Palaninathan, S.K, Sacchettini, J.C, Dias, M.V.B, Bromfield, K.M, Payne, R, Ciulli, A, Howard, N.I, Abell, C, Blundell, T.L, TB Structural Genomics Consortium (TBSGC)
登録日2010-05-24
公開日2010-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis.
Biochem.J., 436, 2011
1SGV
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STRUCTURE OF TRNA PSI55 PSEUDOURIDINE SYNTHASE (TRUB)
分子名称: tRNA pseudouridine synthase B
著者Chaudhuri, B.N, Chan, S, Perry, L.J, Yeates, T.O, TB Structural Genomics Consortium (TBSGC)
登録日2004-02-24
公開日2004-03-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the apo forms of psi 55 tRNA pseudouridine synthase from Mycobacterium tuberculosis: a hinge at the base of the catalytic cleft.
J.Biol.Chem., 279, 2004
1U0T
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Crystal structure of Mycobacterium tuberculosis NAD kinase
分子名称: Inorganic polyphosphate/ATP-NAD kinase
著者Garavaglia, S, Raffaelli, N, Finaurini, L, Magni, G, Rizzi, M, TB Structural Genomics Consortium (TBSGC)
登録日2004-07-14
公開日2004-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis
J.Biol.Chem., 279, 2004
1U5V
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Structure of CitE complexed with triphosphate group of ATP form Mycobacterium tuberculosis
分子名称: ADENOSINE-5'-TRIPHOSPHATE, FORMIC ACID, citE
著者Goulding, C.W, Lerkin, T, Kim, C.Y, Segelke, B, Terwilliger, T, Eisenberg, E, TB Structural Genomics Consortium (TBSGC)
登録日2004-07-28
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis citrate lyase beta subunit and its unusual triphosphate binding site
To be Published
1TXO
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Crystal structure of the Mycobacterium tuberculosis serine/threonine phosphatase PstP/Ppp at 1.95 A.
分子名称: MANGANESE (II) ION, Putative Bacterial Enzyme
著者Pullen, K.E, Ng, H.L, Sung, P.Y, Good, M.C, Smith, S.M, Alber, T, TB Structural Genomics Consortium (TBSGC)
登録日2004-07-05
公開日2004-11-23
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献An Alternate Conformation and a Third Metal in PstP/Ppp, the M. tuberculosis PP2C-Family Ser/Thr Protein Phosphatase.
Structure, 12, 2004
1YL5
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Crystal structure of Mycobacterium tuberculosis dihydrodipicolinate reductase (RV2773C) (crystal form A)
分子名称: Dihydrodipicolinate reductase, MAGNESIUM ION
著者Janowski, R, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2005-01-19
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of dihydrodipicolinate reductase (DapB) from Mycobacterium tuberculosis in three crystal forms.
Acta Crystallogr.,Sect.D, 66, 2010
1S4Q
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Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis (Rv1389)
分子名称: CHLORIDE ION, FORMIC ACID, Guanylate kinase
著者Chan, S, Sawaya, M.R, Perry, L.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2004-01-16
公開日2004-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis
To be Published
1YL7
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the crystal structure of Mycobacterium tuberculosis dihydrodipicolinate reductase (Rv2773c) in complex with NADH (crystal form C)
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Dihydrodipicolinate reductase, MAGNESIUM ION
著者Janowski, R, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2005-01-19
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The structure of dihydrodipicolinate reductase (DapB) from Mycobacterium tuberculosis in three crystal forms.
Acta Crystallogr.,Sect.D, 66, 2010

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件を2024-06-12に公開中

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