3QSA

Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor TAMU-A7)

Summary for 3QSA

• Entry DOI: 10.2210/pdb3qsa/pdb
• Related: 1ZVW 2BPQ 3QQS 3QR9 3QS8
• Descriptor: Anthranilate phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: anthranilate phosphoribosyltransferase, anthranilic acids, magnesium, tryptophan, magnesium binding phosphoribosyl pyrophosphate, transferase-transferase inhibitor complex, structural genomics, tb structural genomics consortium, tbsgc, transferase/transferase inhibitor
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 78805.10

Authors

Castell, A.,Short, F.L.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2011-02-20, release date: 2012-08-22, Last modification date: 2024-02-21)

• Primary citation: Castell, A.,Short, L.F.,Evans, G.,Bulloch, E.M.,Cookson, T.,Parker, E.,Lee, C.,Baker, E.N.,Lott, J.S.; Inhibition of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase by blocking of an active site entrance tunnel.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.18 Å)