1N4G

Structure of CYP121, a Mycobacterial P450, in Complex with Iodopyrazole

Summary for 1N4G

• Entry DOI: 10.2210/pdb1n4g/pdb
• Related: 1N40
• Descriptor: Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, 4-IODOPYRAZOLE, ... (4 entities in total)
• Functional Keywords: p450 fold, iodopyrazole complex, heme binding, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cytoplasm (By similarity): P0A514
• Total number of polymer chains: 1
• Total formula weight: 44116.32

Authors

Leys, D.,Mowat, C.G.,McLean, K.J.,Richmond, A.,Chapman, S.K.,Walkinshaw, M.D.,Munro, A.W.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2002-10-31, release date: 2003-02-04, Last modification date: 2024-02-14)

• Primary citation: Leys, D.,Mowat, C.G.,McLean, K.J.,Richmond, A.,Chapman, S.K.,Walkinshaw, M.D.,Munro, A.W.; Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450.; J.Biol.Chem., 278:5141-5147, 2003; PubMed: 12435731; DOI: 10.1074/jbc.M209928200

Experimental method

X-RAY DIFFRACTION (1.8 Å)