6P7J
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6P50
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![BU of 6p50 by Molmil](/molmil-images/mine/6p50) | Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha Fab 4A10 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7 receptor subunit alpha, anti-IL-7R 4A10 Fab heavy chain, ... | Authors: | Walsh, S.T.R, Kashi, L, Kohnhorst, C.L. | Deposit date: | 2019-05-29 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models. Leukemia, 34, 2020
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6UIZ
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![BU of 6uiz by Molmil](/molmil-images/mine/6uiz) | Artificial Iron Proteins: Modelling the Active Sites in Non-Heme Dioxygenases | Descriptor: | ACETATE ION, Streptavidin, {N-(2-{bis[(pyridin-2-yl-kappaN)methyl]amino-kappaN}ethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(triaza-1,2-dien-2-ium-1-ide-kappaN~1~)iron(4+) | Authors: | Miller, K.R, Paretsky, J.D, Follmer, A.H, Heinisch, T, Mittra, K, Gul, S, Kim, I.-S, Fuller, F.D, Batyuk, A, Sutherlin, K.D, Brewster, A.S, Bhowmick, A, Sauter, N.K, Kern, J, Yano, J, Green, M.T, Ward, T.R, Borovik, A.S. | Deposit date: | 2019-10-01 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Artificial Iron Proteins: Modeling the Active Sites in Non-Heme Dioxygenases. Inorg.Chem., 59, 2020
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4AUK
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![BU of 4auk by Molmil](/molmil-images/mine/4auk) | Crystal structure of C2498 2'-O-ribose methyltransferase RlmM from Escherichia coli | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Punekar, A.S, Shepherd, T.R, Liljeruhm, J, Forster, A.C, Selmer, M. | Deposit date: | 2012-05-18 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna. Nucleic Acids Res., 40, 2012
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6OI9
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![BU of 6oi9 by Molmil](/molmil-images/mine/6oi9) | Crystal Structure of E. coli Biotin Carboxylase Complexed with 7-[3-(aminomethyl)pyrrolidin-1-yl]-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-2-amine | Descriptor: | 1,2-ETHANEDIOL, 7-[(3S)-3-(aminomethyl)pyrrolidin-1-yl]-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-2-amine, Biotin carboxylase | Authors: | Andrews, L.D, Kane, T.R, Dozzo, P, Haglund, C.M, Hilderbrandt, D.J, Linsell, M.S, Machajewski, T, McEnroe, G, Serio, A.W, Wlasichuk, K.B, Neau, D.B, Pakhomova, S, Waldrop, G.L, Sharp, M, Pogliano, J, Cirz, R, Cohen, F. | Deposit date: | 2019-04-09 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase. J.Med.Chem., 62, 2019
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4ATO
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![BU of 4ato by Molmil](/molmil-images/mine/4ato) | New insights into the mechanism of bacterial Type III toxin-antitoxin systems: selective toxin inhibition by a non-coding RNA pseudoknot | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, TOXI, TOXN | Authors: | Short, F.L, Pei, X.Y, Blower, T.R, Ong, S.L, Luisi, B.F, Salmond, G.P.C. | Deposit date: | 2012-05-09 | Release date: | 2012-12-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Selectivity and Self-Assembly in the Control of a Bacterial Toxin by an Antitoxic Noncoding RNA Pseudoknot. Proc.Natl.Acad.Sci.USA, 110, 2013
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4C1O
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![BU of 4c1o by Molmil](/molmil-images/mine/4c1o) | Geobacillus thermoglucosidasius GH family 52 xylosidase | Descriptor: | 1,2-ETHANEDIOL, BETA-XYLOSIDASE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Espina, G, Eley, K, Schneider, T.R, Crennell, S.J, Danson, M.J. | Deposit date: | 2013-08-13 | Release date: | 2014-05-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Novel Beta-Xylosidase Structure from Geobacillus Thermoglucosidasius: The First Crystal Structure of a Glycoside Hydrolase Family Gh52 Enzyme Reveals Unpredicted Similarity to Other Glycoside Hydrolase Folds Acta Crystallogr.,Sect.D, 70, 2014
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1VIB
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![BU of 1vib by Molmil](/molmil-images/mine/1vib) | NMR SOLUTION STRUCTURE OF THE NEUROTOXIN B-IV, 20 STRUCTURES | Descriptor: | NEUROTOXIN B-IV | Authors: | Barnham, K.J, Dyke, T.R, Kem, W.R, Norton, R.S. | Deposit date: | 1996-11-25 | Release date: | 1997-05-15 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Structure of neurotoxin B-IV from the marine worm Cerebratulus lacteus: a helical hairpin cross-linked by disulphide bonding. J.Mol.Biol., 268, 1997
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1WLG
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![BU of 1wlg by Molmil](/molmil-images/mine/1wlg) | Crystal structure of FlgE31, a major fragment of the hook protein | Descriptor: | Flagellar hook protein flgE | Authors: | Samatey, F.A, Matsunami, H, Imada, K, Nagashima, S, Shaikh, T.R, Thomas, D.R, DeRosier, D.J, Kitao, A, Namba, K. | Deposit date: | 2004-06-25 | Release date: | 2004-11-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the bacterial flagellar hook and implication for the molecular universal joint mechanism. Nature, 431, 2004
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6UI0
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![BU of 6ui0 by Molmil](/molmil-images/mine/6ui0) | Artificial Iron Proteins: Modelling the Active Sites in Non-Heme Dioxygenases | Descriptor: | ACETATE ION, Streptavidin, {N-(2-{bis[(pyridin-2-yl-kappaN)methyl]amino-kappaN}ethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}iron(3+) | Authors: | Miller, K.R, Paretsky, J.D, Follmer, A.H, Heinisch, T, Mittra, K, Gul, S, Kim, I.-S, Fuller, F.D, Batyuk, A, Sutherlin, K.D, Brewster, A.S, Bhowmick, A, Sauter, N.K, Kern, J, Yano, J, Green, M.T, Ward, T.R, Borovik, A.S. | Deposit date: | 2019-09-29 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Artificial Iron Proteins: Modeling the Active Sites in Non-Heme Dioxygenases. Inorg.Chem., 59, 2020
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1W7Z
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![BU of 1w7z by Molmil](/molmil-images/mine/1w7z) | Crystal structure of the free (uncomplexed) Ecballium elaterium trypsin inhibitor (EETI-II) | Descriptor: | FORMIC ACID, SODIUM ION, TRYPSIN INHIBITOR II | Authors: | Kraetzner, R, Debreczeni, J.E, Pape, T, Kolmar, H, Schneider, T.R, Uson, I, Scheldrick, G.M. | Deposit date: | 2004-09-14 | Release date: | 2005-11-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structure of Ecballium Elaterium Trypsin Inhibitor II (Eeti-II): A Rigid Molecular Scaffold Acta Crystallogr.,Sect.D, 61, 2005
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4ATN
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![BU of 4atn by Molmil](/molmil-images/mine/4atn) | Crystal structure of C2498 2'-O-ribose methyltransferase RlmM from Escherichia coli | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M, ... | Authors: | Punekar, A.S, Shepherd, T.R, Liljeruhm, J, Forster, A.C, Selmer, M. | Deposit date: | 2012-05-08 | Release date: | 2012-08-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna. Nucleic Acids Res., 40, 2012
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4AX1
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![BU of 4ax1 by Molmil](/molmil-images/mine/4ax1) | Q157N mutant. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 | Descriptor: | ACETATE ION, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Leiros, H.-K.S, Borra, P.S, Brandsdal, B.O, Edvardsen, K.S.W, Spencer, J, Walsh, T.R, Samuelsen, O. | Deposit date: | 2012-06-06 | Release date: | 2012-06-20 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157 Antimicrob.Agents Chemother., 56, 2012
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1US0
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![BU of 1us0 by Molmil](/molmil-images/mine/1us0) | Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom | Descriptor: | ALDOSE REDUCTASE, CITRIC ACID, IDD594, ... | Authors: | Howard, E.I, Sanishvili, R, Cachau, R.E, Mitschler, A, Chevrier, B, Barth, P, Lamour, V, Van Zandt, M, Sibley, E, Bon, C, Moras, D, Schneider, T.R, Joachimiak, A, Podjarny, A. | Deposit date: | 2003-11-16 | Release date: | 2004-05-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (0.66 Å) | Cite: | Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A. Proteins, 55, 2004
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1NBQ
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![BU of 1nbq by Molmil](/molmil-images/mine/1nbq) | Crystal Structure of Human Junctional Adhesion Molecule Type 1 | Descriptor: | Junctional adhesion molecule 1 | Authors: | Prota, A.E, Campbell, J.A, Schelling, P, Forrest, J.C, Watson, M.J, Peters, T.R, Aurrand-Lions, M, Imhof, B.A, Dermody, T.S, Stehle, T. | Deposit date: | 2002-12-03 | Release date: | 2003-04-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding Proc.Natl.Acad.Sci.USA, 100, 2003
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1X0N
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![BU of 1x0n by Molmil](/molmil-images/mine/1x0n) | NMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor | Descriptor: | 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID, Growth factor receptor-bound protein 2 | Authors: | Ogura, K, Shiga, T, Yuzawa, S, Yokochi, M, Burke, T.R, Inagaki, F. | Deposit date: | 2005-03-24 | Release date: | 2005-04-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor To be Published
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8C24
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8C26
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4BLG
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![BU of 4blg by Molmil](/molmil-images/mine/4blg) | Crystal structure of MHV-68 Latency-associated nuclear antigen (LANA) C-terminal DNA binding domain | Descriptor: | LATENCY-ASSOCIATED NUCLEAR ANTIGEN, PHOSPHATE ION | Authors: | Correia, B, Cerqueira, S.A, Beauchemin, C, Pires De Miranda, M, Li, S, Ponnusamy, R, Rodrigues, L, Schneider, T.R, Carrondo, M.A, Kaye, K.M, Simas, J.P, McVey, C.E. | Deposit date: | 2013-05-02 | Release date: | 2013-10-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Gamma-2 Herpesvirus Lana DNA Binding Domain Identifies Charged Surface Residues which Impact Viral Latency Plos Pathog., 9, 2013
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1UPD
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![BU of 1upd by Molmil](/molmil-images/mine/1upd) | Oxidized STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6 | Descriptor: | CYTOCHROME C3, HEME C | Authors: | Bento, I, Matias, P.M, Baptista, A.M, Da Costa, P.N, Van Dongen, W.M.A.M, Saraiva, L.M, Schneider, T.R, Soares, C.M, Carrondo, M.A. | Deposit date: | 2003-09-29 | Release date: | 2004-09-30 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6 Proteins, 54, 2004
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6UOG
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![BU of 6uog by Molmil](/molmil-images/mine/6uog) | Asparaginase II from Escherichia coli | Descriptor: | ASPARTIC ACID, L-asparaginase 2 | Authors: | Araujo, T.S, Almeida, M.S, Lima, L.M.T.R. | Deposit date: | 2019-10-14 | Release date: | 2020-10-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Biophysical characterization of two commercially available preparations of the drug containing Escherichia coli L-Asparaginase 2. Biophys.Chem., 271, 2021
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6VE1
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6UOD
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![BU of 6uod by Molmil](/molmil-images/mine/6uod) | Asparaginase II from Escherichia coli | Descriptor: | L-asparaginase 2 | Authors: | Araujo, T.S, Almeida, M.S, Lima, L.M.T.R. | Deposit date: | 2019-10-14 | Release date: | 2020-10-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biophysical characterization of two commercially available preparations of the drug containing Escherichia coli L-Asparaginase 2. Biophys.Chem., 271, 2021
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1UP9
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![BU of 1up9 by Molmil](/molmil-images/mine/1up9) | REDUCED STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6 | Descriptor: | CYTOCHROME C3, HEME C, SULFATE ION | Authors: | Bento, I, Matias, P.M, Baptista, A.M, Da Costa, P.N, Van Dongen, W.M.A.M, Saraiva, L.M, Schneider, T.R, Soares, C.M, Carrondo, M.A. | Deposit date: | 2003-09-29 | Release date: | 2004-09-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6 Proteins, 54, 2004
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4C1P
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![BU of 4c1p by Molmil](/molmil-images/mine/4c1p) | Geobacillus thermoglucosidasius GH family 52 xylosidase | Descriptor: | BETA-XYLOSIDASE, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | Authors: | Espina, G, Eley, K, Schneider, T.R, Crennell, S.J, Danson, M.J. | Deposit date: | 2013-08-13 | Release date: | 2014-05-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.634 Å) | Cite: | A Novel Beta-Xylosidase Structure from Geobacillus Thermoglucosidasius: The First Crystal Structure of a Glycoside Hydrolase Family Gh52 Enzyme Reveals Unpredicted Similarity to Other Glycoside Hydrolase Folds Acta Crystallogr.,Sect.D, 70, 2014
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