8C26
ParDE2 toxin-antitoxin complex from Mycobacterium tuberculosis (rv2142A-rv2142c)
Summary for 8C26
| Entry DOI | 10.2210/pdb8c26/pdb |
| Descriptor | Toxin ParE2, Antitoxin ParD2, CHLORIDE ION (3 entities in total) |
| Functional Keywords | toxin-antitoxin gyrase inhibitor tuberculosis, toxin |
| Biological source | Mycobacterium tuberculosis H37Rv More |
| Total number of polymer chains | 2 |
| Total formula weight | 20323.52 |
| Authors | Beck, I.N.,Blower, T.R. (deposition date: 2022-12-21, release date: 2023-12-20, Last modification date: 2024-03-27) |
| Primary citation | Beck, I.N.,Arrowsmith, T.J.,Grobbelaar, M.J.,Bromley, E.H.C.,Marles-Wright, J.,Blower, T.R. Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition. Nucleic Acids Res., 52:1909-1929, 2024 Cited by PubMed: 38113275DOI: 10.1093/nar/gkad1220 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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