8F8L
 
 | | The structure of Rv2173 from M. tuberculosis with DMAP bound | | 分子名称: | (2E,6E)-farnesyl diphosphate synthase, CALCIUM ION, DIMETHYLALLYL DIPHOSPHATE, ... | | 著者 | Johnston, J.M, Allison, T.M, Titterington, J. | | 登録日 | 2022-11-22 | | 公開日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The structure of Rv2173 from M. tuberculosis in APO-, IPP-, and DMAP-bound forms.
To be Published
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8ST6
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8SV2
 | | Pasteurella multocida alpha2,3/2,6 sialyltransferase D141N bound to CMP | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-2,3/2,6-sialyltransferase/sialidase, CYTIDINE-5'-MONOPHOSPHATE, ... | | 著者 | Stubbs, H.E, Iverson, T.M. | | 登録日 | 2023-05-15 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Pasteurella multocida alpha2,3/2,6 sialyltransferase D141N bound to CMP
To Be Published
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1S72
 | | REFINED CRYSTAL STRUCTURE OF THE HALOARCULA MARISMORTUI LARGE RIBOSOMAL SUBUNIT AT 2.4 ANGSTROM RESOLUTION | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L11P, ... | | 著者 | Klein, D.J, Schmeing, T.M, Moore, P.B, Steitz, T.A. | | 登録日 | 2004-01-28 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Roles of Ribosomal Proteins in the Structure, Assembly and Evolution of the Large Ribosomal Subunit
J.Mol.Biol., 340, 2004
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8TWU
 | | Crystal structure of Cytochrome P450 AspB bound to N1-methylated cyclo-L-Trp-L-Pro | | 分子名称: | (3S,5S,8aS)-3-[(1-methyl-1H-indol-3-yl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, Cytochrome P450 AspB, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Gering, H.E, Li, X, Tang, H, Swartz, P.D, Chang, W.-C, Makris, T.M. | | 登録日 | 2023-08-21 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization.
J.Am.Chem.Soc., 145, 2023
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8FEX
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8C7F
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8CBA
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4D2T
 | | Structure of MELK in complex with inhibitors | | 分子名称: | 3-[2-(phenylcarbamoyl)-5-(1H-pyrazol-4-yl)phenoxy]propan-1-aminium, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | | 著者 | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | | 登録日 | 2014-05-13 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase
Acs Med.Chem.Lett., 6, 2015
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3W16
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3W10
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3W1D
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3W1C
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3VZU
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3W18
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8UAE
 | | E. coli Sir2_HerA complex (12:6) with ATPgamaS | | 分子名称: | MAGNESIUM ION, Nucleoside triphosphate hydrolase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | | 登録日 | 2023-09-20 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
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8UAF
 | | E. coli Sir2_HerA complex (12:6) bound with NAD+ | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | | 登録日 | 2023-09-20 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
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4DBS
 | | Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) in complex with NADP+ and 3'-[(4-nitronaphthalen-1-yl)amino]benzoic acid | | 分子名称: | 3-[(4-nitronaphthalen-1-yl)amino]benzoic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Chen, M, Christianson, D.W, Winkler, J.D, Penning, T.M. | | 登録日 | 2012-01-16 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | | 主引用文献 | Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer.
Bioorg.Med.Chem.Lett., 22, 2012
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8FTF
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8FTE
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8FXH
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8FXI
 | | Cryo-EM structure of Stanieria sp. CphA2 in complex with ADPCP and 4x(beta-Asp-Arg) | | 分子名称: | 1-[(4-aminopyrimidin-5-yl)amino]-2,5-anhydro-1-deoxy-6-O-[(S)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]oxy}phosphoryl]-D-allitol, 4x(beta-Asp-Arg), MAGNESIUM ION, ... | | 著者 | Markus, L.M, Sharon, I, Strauss, M, Schmeing, T.M. | | 登録日 | 2023-01-24 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structure and function of a hexameric cyanophycin synthetase 2.
Protein Sci., 32, 2023
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8FFI
 | | Structure of tetramerized MapSPARTA upon guide RNA-mediated target DNA binding | | 分子名称: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | | 著者 | Shen, Z.F, Yang, X.Y, Fu, T.M. | | 登録日 | 2022-12-08 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
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4D7P
 | | Superoxide reductase (1Fe-SOR) from Giardia intestinalis | | 分子名称: | FE (III) ION, SUPEROXIDE REDUCTASE | | 著者 | Sousa, C.M, Carpentier, P, Matias, P.M, Testa, F, Pinho, F.G, Sarti, P, Giuffre, A, Bandeiras, T.M, Romao, C.V. | | 登録日 | 2014-11-26 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Superoxide Reductase from Giardia Intestinalis: Structural Characterization of the First Sor from a Eukaryotic Organism Shows an Iron Centre that is Highly Sensitive to Photoreduction.
Acta Crystallogr.,Sect.D, 71, 2015
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8DGA
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IV | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B, ... | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
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