8FYO
 
 | | MicroED structure of Proteinase K from lamellae milled from multiple plasma sources | | 分子名称: | CALCIUM ION, NITRATE ION, Proteinase K | | 著者 | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | | 登録日 | 2023-01-26 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.39 Å) | | 主引用文献 | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals.
Nat Commun, 14, 2023
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5ZXB
 | | Crystal structure of ACK1 with compound 10d | | 分子名称: | Activated CDC42 kinase 1, N-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide | | 著者 | Hong, E.M, Kim, H.L, Sim, T.B. | | 登録日 | 2018-05-18 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.
J. Med. Chem., 61, 2018
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7ULY
 | | MicroED structure of triclinic lysozyme | | 分子名称: | Lysozyme C, NITRATE ION | | 著者 | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Gonen, T. | | 登録日 | 2022-04-05 | | 公開日 | 2023-03-15 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.87 Å) | | 主引用文献 | Hydrogens and hydrogen-bond networks in macromolecular MicroED data.
J Struct Biol X, 6, 2022
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3ZQL
 | | DNA-bound form of TetR-like repressor SimR | | 分子名称: | 5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*CP*CP*GP*TP*AP*DCP *GP*AP*A)-3', 5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*GP*CP*GP*TP*AP*DCP *GP*AP*A)-3', PUTATIVE REPRESSOR SIMREG2 | | 著者 | Le, T.B.K, Schumacher, M.A, Lawson, D.M, Brennan, R.G, Buttner, M.J. | | 登録日 | 2011-06-10 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The Crystal Structure of the Tetr Family Transcriptional Repressor Simr Bound to DNA and the Role of a Flexible N-Terminal Extension in Minor Groove Binding.
Nucleic Acids Res., 39, 2011
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5BN6
 | | Crystal Structure of Frutalin from Artocarpus incisa in complex with galactose | | 分子名称: | Jacalin, beta-D-galactopyranose | | 著者 | Vieira Neto, A.E, Pereira, H.M, Moreno, F.B.M.B, Moreira, A.C.O.M, Lobo, M.D.P, Sousa, F.D, Grangeiro, T.B, Moreira, R.A. | | 登録日 | 2015-05-25 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6499 Å) | | 主引用文献 | Crystal Structure of Frutalin from Artocarpus incisa in complex with galactose
To Be Published
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5KTH
 | | Structure of cow mincle complexed with brartemicin | | 分子名称: | 2,4-dihydroxy-6-methyl Benzoic acid, CALCIUM ION, TRIETHYLENE GLYCOL, ... | | 著者 | Feinberg, H, Rambaruth, N.D.S, Jegouzo, S.A.F, Jacobsen, K.M, Djurhuus, R, Poulsen, T.B, Taylor, M.E, Drickamer, K, Weis, W.I. | | 登録日 | 2016-07-11 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
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5DD0
 | | Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | | 分子名称: | ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide | | 著者 | Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. | | 登録日 | 2015-08-24 | | 公開日 | 2016-05-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.488 Å) | | 主引用文献 | Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
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5DD1
 | | Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | | 分子名称: | ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN | | 著者 | Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. | | 登録日 | 2015-08-24 | | 公開日 | 2016-05-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.597 Å) | | 主引用文献 | Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
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4WOG
 | | Crystal Structure of Frutalin from Artocarpus incisa | | 分子名称: | Frutalin | | 著者 | Pereira, H.M, Moreira, A.C.O.M, Vieira Neto, A.E, Moreno, F.B.M.B, Lobo, M.D.P, Sousa, F.D, Grangeiro, T.B, Moreira, R.A. | | 登録日 | 2014-10-15 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.813 Å) | | 主引用文献 | Crystal Structure of Frutalin from Artocarpus incisa
To Be Published
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5KTI
 | | Structure of cow mincle complexed with KMJ1 | | 分子名称: | 2,3-dimethoxybenzoic acid, CALCIUM ION, TRIETHYLENE GLYCOL, ... | | 著者 | Feinberg, H, Rambaruth, N.D.S, Jegouzo, S.A.F, Jacobsen, K.M, Djurhuus, R, Poulsen, T.B, Taylor, M.E, Drickamer, K, Weis, W.I. | | 登録日 | 2016-07-11 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
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4X1J
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5DYH
 | | Ti(IV) bound human serum transferrin | | 分子名称: | CARBONATE ION, CITRIC ACID, Serotransferrin, ... | | 著者 | Saxena, M, Sharma, S, Noinaj, N, Parks, T.B, Tinoco, A.D. | | 登録日 | 2015-09-24 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.682 Å) | | 主引用文献 | Unusual Synergism of Transferrin and Citrate in the Regulation of Ti(IV) Speciation, Transport, and Toxicity.
J.Am.Chem.Soc., 138, 2016
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6MAA
 | | WFIKKN2 Follistatin Domain | | 分子名称: | NITRATE ION, WAP, Kazal, ... | | 著者 | McCoy, J.C, Walker, R.G, Thomas, T.B. | | 登録日 | 2018-08-27 | | 公開日 | 2019-03-06 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.394 Å) | | 主引用文献 | Crystal structure of the WFIKKN2 follistatin domain reveals insight into how it inhibits growth differentiation factor 8 (GDF8) and GDF11.
J.Biol.Chem., 294, 2019
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5GPO
 | | The sensor domain structure of the zinc-responsive histidine kinase CzcS from Pseudomonas Aeruginosa | | 分子名称: | SULFATE ION, Sensor protein CzcS, ZINC ION | | 著者 | Wang, D, Chen, W.Z, Huang, S.Q, Liu, X.C, Hu, Q.Y, Wei, T.B, Gan, J.H, Chen, H. | | 登録日 | 2016-08-03 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Structural basis of Zn(II) induced metal detoxification and antibiotic resistance by histidine kinase CzcS in Pseudomonas aeruginosa
PLoS Pathog., 13, 2017
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6MAC
 | | Ternary structure of GDF11 bound to ActRIIB-ECD and Alk5-ECD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 11, ... | | 著者 | Goebel, E.J, Thompson, T.B. | | 登録日 | 2018-08-27 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5K3V
 | | apo-PDX1.3 (Arabidopsis) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... | | 著者 | Robinson, G.C, Kaufmann, M, Roux, C, Fitzpatrick, T.B. | | 登録日 | 2016-05-20 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural definition of the lysine swing in Arabidopsis thaliana PDX1: Intermediate channeling facilitating vitamin B6 biosynthesis.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5K2Z
 | | PDX1.3-adduct (Arabidopsis) | | 分子名称: | 1,2-ETHANEDIOL, 2-azanylpenta-1,4-dien-3-one, CHLORIDE ION, ... | | 著者 | Robinson, G.C, Kaufmann, M, Roux, C, Fitzpatrick, T.B. | | 登録日 | 2016-05-19 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural definition of the lysine swing in Arabidopsis thaliana PDX1: Intermediate channeling facilitating vitamin B6 biosynthesis.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1TM0
 | | Crystal Structure of the putative proline racemase from Brucella melitensis, Northeast Structural Genomics Target LR31 | | 分子名称: | PROLINE RACEMASE | | 著者 | Forouhar, F, Chen, Y, Xiao, R, Ho, C.K, Ma, L.-C, Cooper, B, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-06-10 | | 公開日 | 2004-06-29 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Functional insights from structural genomics.
J.STRUCT.FUNCT.GENOM., 8, 2007
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5KSV
 | | Crystal structure of HLA-DQ2.5-CLIP2 | | 分子名称: | HLA class II histocompatibility antigen gamma chain, MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta-1 | | 著者 | Nguyen, T.B, Jayaraman, P, Bergseng, E, Madhusudhan, M.S, Kim, C.-Y, Sollid, L.M. | | 登録日 | 2016-07-10 | | 公開日 | 2017-04-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.195 Å) | | 主引用文献 | Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.
J. Biol. Chem., 292, 2017
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1T82
 | | Crystal Structure of the putative thioesterase from Shewanella oneidensis, Northeast Structural Genomics Target SoR51 | | 分子名称: | hypothetical acetyltransferase | | 著者 | Forouhar, F, Lee, I, Vorobiev, S.M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-05-11 | | 公開日 | 2004-05-18 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of the putative thioesterase from Shewanella oneidensis, Northeast Structural Genomics Target SoR51
TO BE PUBLISHED
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1TIQ
 | | Crystal Structure of an Acetyltransferase (PaiA) in complex with CoA and DTT from Bacillus subtilis, Northeast Structural Genomics Target SR64. | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, COENZYME A, Protease synthase and sporulation negative regulatory protein PAI 1, ... | | 著者 | Forouhar, F, Lee, I, Shen, J, Vorobiev, S.M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2004-06-02 | | 公開日 | 2004-07-13 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase.
J.Biol.Chem., 280, 2005
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7Z7D
 | | Tubulin-Todalam-Vinblastine-complex | | 分子名称: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Muehlethaler, T, Milanos, L, Ortega, J.A, Blum, T.B, Gioia, D, Roy, B, Prota, A.E, Cavalli, A, Steinmetz, M.O. | | 登録日 | 2022-03-15 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action.
Angew.Chem.Int.Ed.Engl., 61, 2022
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6Y93
 | | Crystal structure of the DNA-binding domain of the Nucleoid Occlusion Factor (Noc) complexed to the Noc-binding site (NBS) | | 分子名称: | Noc Binding Site (NBS), Nucleoid occlusion protein | | 著者 | Jalal, A.S.B, Tran, N.T, Stevenson, C.E.M, Chan, E, Lo, R, Tan, X, Noy, A, Lawson, D.M, Le, T.B.K. | | 登録日 | 2020-03-06 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Diversification of DNA-Binding Specificity by Permissive and Specificity-Switching Mutations in the ParB/Noc Protein Family.
Cell Rep, 32, 2020
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7BM8
 | | Crystal structure of the C-terminally truncated chromosome-partitioning protein ParB from Caulobacter crescentus complexed with CTP-gamma-S | | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, Chromosome-partitioning protein ParB, MAGNESIUM ION | | 著者 | Jalal, A.S, Tran, N.T, Stevenson, C.E.M, Lawson, D.M, Le, T.B.K. | | 登録日 | 2021-01-19 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | A CTP-dependent gating mechanism enables ParB spreading on DNA.
Elife, 10, 2021
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6YMB
 | | MicroED structure of human carbonic anhydrase II | | 分子名称: | ZINC ION, carbonic anhydrase 2 | | 著者 | Clabbers, M.T.B, Fisher, S.Z, Coincon, M, Zou, X, Xu, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.5 Å) | | 主引用文献 | Visualizing drug binding interactions using microcrystal electron diffraction.
Commun Biol, 3, 2020
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