5KTI

Structure of cow mincle complexed with KMJ1

Summary for 5KTI

• Entry DOI: 10.2210/pdb5kti/pdb
• Related: 5KTH
• Related PRD ID: PRD_900006
• Descriptor: mincle protein, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, 2,3-dimethoxybenzoic acid, ... (6 entities in total)
• Functional Keywords: glycobiology, carbohydrate-binding protein, c-type lectin, complex, sugar binding protein
• Biological source: Bos taurus (Bovine)
• Total number of polymer chains: 1
• Total formula weight: 18094.27

Authors

Feinberg, H.,Rambaruth, N.D.S.,Jegouzo, S.A.F.,Jacobsen, K.M.,Djurhuus, R.,Poulsen, T.B.,Taylor, M.E.,Drickamer, K.,Weis, W.I. (deposition date: 2016-07-11, release date: 2016-08-31, Last modification date: 2023-10-04)

• Primary citation: Feinberg, H.,Rambaruth, N.D.,Jegouzo, S.A.,Jacobsen, K.M.,Djurhuus, R.,Poulsen, T.B.,Weis, W.I.,Taylor, M.E.,Drickamer, K.; Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.; J.Biol.Chem., 291:21222-21233, 2016; PubMed: 27542410; DOI: 10.1074/jbc.M116.749515

Experimental method

X-RAY DIFFRACTION (1.8 Å)