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PDB: 16 件
2K1D
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BU of 2k1d by Molmil
NMR Studies of a Pathogenic Mutant (D178N) of the Human Prion Protein
分子名称: Major prion protein
著者Mills, J.L, Surewicz, K, Surewicz, W.K, Sonnichsen, F.D.
登録日2008-02-29
公開日2009-03-03
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Residue 129 polymorphism and conformational dynamics of familial prion diseases associated with the human prion protein variant D178N
To be Published
3HEQ
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BU of 3heq by Molmil
Human prion protein variant D178N with M129
分子名称: CADMIUM ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-10
公開日2010-01-12
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HES
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BU of 3hes by Molmil
Human prion protein variant F198S with M129
分子名称: CADMIUM ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-10
公開日2010-01-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HAF
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BU of 3haf by Molmil
Human prion protein variant V129 domain swapped dimer
分子名称: CADMIUM ION, CHLORIDE ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-01
公開日2010-01-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HAK
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BU of 3hak by Molmil
Human prion protein variant V129
分子名称: Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-01
公開日2010-01-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HER
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BU of 3her by Molmil
Human prion protein variant F198S with V129
分子名称: CADMIUM ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-10
公開日2010-01-12
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HJX
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BU of 3hjx by Molmil
Human prion protein variant D178N with V129
分子名称: CADMIUM ION, CHLORIDE ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-22
公開日2010-01-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HJ5
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BU of 3hj5 by Molmil
Human prion protein variant V129 domain swapped dimer
分子名称: Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-20
公開日2010-01-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
8DJA
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BU of 8dja by Molmil
Cryo-EM structure of mouse PrP23-144 amyloid fibrils (polymorph 1)
分子名称: Major prion protein
著者Li, Q, Surewicz, W.K.
登録日2022-06-30
公開日2022-09-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Cryo-EM structure of disease-related prion fibrils provides insights into seeding barriers.
Nat.Struct.Mol.Biol., 29, 2022
7RL4
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BU of 7rl4 by Molmil
Cryo-EM structure of human PrP23-144 amyloid fibrils
分子名称: Major prion protein
著者Li, Q, Surewicz, W.K.
登録日2021-07-23
公開日2022-07-27
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Cryo-EM structure of disease-related prion fibrils provides insights into seeding barriers.
Nat.Struct.Mol.Biol., 29, 2022
7KWZ
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BU of 7kwz by Molmil
TDP-43 LCD amyloid fibrils
分子名称: Isoform 2 of TAR DNA-binding protein 43
著者Li, Q, Babinchak, W.M, Surewicz, W.K.
登録日2020-12-02
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of amyloid fibrils formed by the entire low complexity domain of TDP-43.
Nat Commun, 12, 2021
1I4M
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BU of 1i4m by Molmil
Crystal structure of the human prion protein reveals a mechanism for oligomerization
分子名称: CADMIUM ION, CHLORIDE ION, MAJOR PRION PROTEIN
著者Knaus, K.J, Morillas, M, Swietnicki, W, Malone, M, Surewicz, W.K, Yee, V.C.
登録日2001-02-22
公開日2002-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the human prion protein reveals a mechanism for oligomerization.
Nat.Struct.Biol., 8, 2001
1FKC
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BU of 1fkc by Molmil
HUMAN PRION PROTEIN (MUTANT E200K) FRAGMENT 90-231
分子名称: PRION PROTEIN
著者Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D.
登録日2000-08-09
公開日2000-09-21
最終更新日2018-03-14
実験手法SOLUTION NMR
主引用文献Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
1FO7
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BU of 1fo7 by Molmil
HUMAN PRION PROTEIN MUTANT E200K FRAGMENT 90-231
分子名称: PRION PROTEIN
著者Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D.
登録日2000-08-25
公開日2000-09-21
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
4E1H
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BU of 4e1h by Molmil
Fragment of human prion protein
分子名称: CITRIC ACID, FE (III) ION, Major prion protein
著者Apostol, M.I, Perry, K, Surewicz, W.K.
登録日2012-03-06
公開日2013-03-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of a human prion protein fragment reveals a motif for oligomer formation.
J.Am.Chem.Soc., 135, 2013
4E1I
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BU of 4e1i by Molmil
Fragment of human prion protein
分子名称: Major prion protein
著者Apostol, M.I, Surewicz, W.K.
登録日2012-03-06
公開日2013-03-06
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of a human prion protein fragment reveals a motif for oligomer formation.
J.Am.Chem.Soc., 135, 2013

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件を2024-10-30に公開中

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