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PDB: 108 results

4Y89
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Crystal structure of the N-terminal domain of CEACAM7
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 7
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-09-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structure of the N-terminal dimerization domain of CEACAM7.
Acta Crystallogr.,Sect.F, 71, 2015
4YIQ
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Structure of the CEACAM6-CEACAM8 heterodimer
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 6, Carcinoembryonic antigen-related cell adhesion molecule 8, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-03-02
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
6O1C
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BU of 6o1c by Molmil
Alpha-L-fucosidase AlfC D200A mutant in complex with 4-nitrophenyl-a-L-fucopyranoside substrate
Descriptor: 4-nitrophenyl 6-deoxy-alpha-L-galactopyranoside, AlfC
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-19
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
5VI4
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IL-33/ST2/IL-1RAcP ternary complex structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein, Interleukin-1 receptor-like 1, ...
Authors:Guenther, S, Sundberg, E.J.
Deposit date:2017-04-13
Release date:2017-09-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.792 Å)
Cite:IL-1 Family Cytokines Use Distinct Molecular Mechanisms to Signal through Their Shared Co-receptor.
Immunity, 47, 2017
4Y88
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Crystal structure of the N-terminal domain of CEACAM8
Descriptor: 1,3-PROPANDIOL, CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 8, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
7LFN
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Structure of Hyperglycosylated Human IgG1 Fc (Fc267_329)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc (Fc267_329), alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Fields, J.K, Sundberg, E.J.
Deposit date:2021-01-17
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
To Be Published
6O1A
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Alpha-L-fucosidase AlfC from Lactobacillus casei in complex with alpha-L-fucose product
Descriptor: AlfC, beta-L-fucopyranose
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-18
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6O1J
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Alpha-L-fucosidase AlfC fucosyltransferase mutant N243A
Descriptor: AlfC, beta-L-fucopyranose
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-20
Release date:2020-02-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6O18
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Unliganded alpha-L-fucosidase AlfC from Lactobacillus casei
Descriptor: AlfC
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-18
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
6C3U
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Crystal structure of Klebsiella pneumoniae fosfomycin resistance protein (FosAKP) with inhibitor (ANY2) bound
Descriptor: 3-bromo-6-(4-nitro-1H-pyrazol-3-yl)pyrazolo[1,5-a]pyrimidin-2(1H)-one, FosA family fosfomycin resistance glutathione transferase, GLYCEROL, ...
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2018-01-10
Release date:2018-12-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens.
Antimicrob. Agents Chemother., 63, 2019
1T7A
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Crystal structure of mutant Lys8Asp of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch
Descriptor: Alpha-like neurotoxin BmK-I
Authors:Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C.
Deposit date:2004-05-08
Release date:2004-09-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
5VAW
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Fusion of Maltose-binding Protein and PilA from Acinetobacter baumannii AB5075
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLUTAMIC ACID, LYSINE, ...
Authors:Piepenbrink, K.H, Sundberg, E.J.
Deposit date:2017-03-28
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:The structure of PilA fromAcinetobacter baumanniiAB5075 suggests a mechanism for functional specialization inAcinetobactertype IV pili.
J. Biol. Chem., 294, 2019
6AW2
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BU of 6aw2 by Molmil
Crystal structure of the HopQ-CEACAM1 complex
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, HopQ
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AW3
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Crystal structure of the HopQ-CEACAM3 L44Q complex
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 3, HopQ
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6O1I
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Alpha-L-fucosidase AlfC fucosyltransferase mutant E274A
Descriptor: AlfC
Authors:Klontz, E.H, Sundberg, E.J.
Deposit date:2019-02-20
Release date:2020-02-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020
4OGM
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MBP-fusion protein of PilA1 residues 26-159
Descriptor: Maltose ABC transporter periplasmic protein, pilin protein chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Piepenbrink, K.H, Sundberg, E.J.
Deposit date:2014-01-16
Release date:2015-01-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.234 Å)
Cite:Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile.
Structure, 23, 2015
4PE2
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MBP PilA1 CD160
Descriptor: MALONATE ION, Maltose ABC transporter periplasmic protein,Prepilin-type N-terminal cleavage/methylation domain protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Piepenbrink, K.H, Sundberg, E.J.
Deposit date:2014-04-22
Release date:2015-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.724 Å)
Cite:Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile.
Structure, 23, 2015
1L0Y
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T cell receptor beta chain complexed with superantigen SpeA soaked with zinc
Descriptor: 14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL, ...
Authors:Li, H, Sundberg, E.J, Mariuzza, R.A.
Deposit date:2002-02-14
Release date:2002-04-03
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
1L0X
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TCR beta chain complexed with streptococcal superantigen SpeA
Descriptor: 14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL
Authors:Li, H, Sundberg, E.J, Mariuzza, R.A.
Deposit date:2002-02-14
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
2AQ3
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Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3
Descriptor: Enterotoxin type C-3, T-cell receptor beta chain V
Authors:Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
Deposit date:2005-08-17
Release date:2006-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
4P0L
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Crystal Structure of Double Loop-Swapped Interleukin-36Ra With Additional Point Mutations
Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein
Authors:Guenther, S, Sundberg, E.J.
Deposit date:2014-02-21
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor.
J Immunol., 193, 2014
4P0K
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Crystal Structure of Double Loop-Swapped Interleukin-36Ra
Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein
Authors:Guenther, S, Sundberg, E.J.
Deposit date:2014-02-21
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor.
J Immunol., 193, 2014
4P0J
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BU of 4p0j by Molmil
Crystal Structure of Loop-Swapped Interleukin-36Ra
Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein
Authors:Guenther, S, Sundberg, E.J.
Deposit date:2014-02-21
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor.
J Immunol., 193, 2014
4NUY
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Crystal structure of EndoS, an endo-beta-N-acetyl-glucosaminidase from Streptococcus pyogenes
Descriptor: CALCIUM ION, Endo-beta-N-acetylglucosaminidase F2
Authors:Trastoy, B, Guenther, S, Snyder, G.A, Sundberg, E.J.
Deposit date:2013-12-04
Release date:2014-04-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.609 Å)
Cite:Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NUZ
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Crystal structure of a glycosynthase mutant (D233Q) of EndoS, an endo-beta-N-acetyl-glucosaminidase from Streptococcus pyogenes
Descriptor: CALCIUM ION, Endo-beta-N-acetylglucosaminidase F2
Authors:Trastoy, B, Guenther, S, Snyder, G.A, Sundberg, E.J.
Deposit date:2013-12-04
Release date:2014-04-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.905 Å)
Cite:Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.
Proc.Natl.Acad.Sci.USA, 111, 2014

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