2NTS
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![BU of 2nts by Molmil](/molmil-images/mine/2nts) | Crystal Structure of SEK-hVb5.1 | Descriptor: | Staphylococcal enterotoxin K, TRBC1 protein | Authors: | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | Deposit date: | 2006-11-08 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel loop domain in superantigens extends their T cell receptor recognition site J.Mol.Biol., 371, 2007
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8A64
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![BU of 8a64 by Molmil](/molmil-images/mine/8a64) | cryoEM structure of the catalytically inactive EndoS from S. pyogenes in complex with the Fc region of immunoglobulin G1. | Descriptor: | Endo-beta-N-acetylglucosaminidase F2, Immunoglobulin gamma-1 heavy chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Trastoy, B, Cifuente, J.O, Du, J.J, Sundberg, E.J, Guerin, M.E. | Deposit date: | 2022-06-16 | Release date: | 2023-04-05 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases. Nat Commun, 14, 2023
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3MFG
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![BU of 3mfg by Molmil](/molmil-images/mine/3mfg) | |
8VFU
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![BU of 8vfu by Molmil](/molmil-images/mine/8vfu) | |
4IZE
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![BU of 4ize by Molmil](/molmil-images/mine/4ize) | Crystal Structure of IL-36gamma | Descriptor: | Interleukin-36 gamma | Authors: | Guenther, S, Sundberg, E.J. | Deposit date: | 2013-01-29 | Release date: | 2014-06-25 | Last modified: | 2014-07-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J.Immunol., 193, 2014
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8TTM
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![BU of 8ttm by Molmil](/molmil-images/mine/8ttm) | IgG1 Fc Heterodimer combYSelect1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain | Authors: | Azzam, T, Du, J.J, Sundberg, E.J. | Deposit date: | 2023-08-14 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers. Sci Adv, 10, 2024
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8TUD
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![BU of 8tud by Molmil](/molmil-images/mine/8tud) | IgG1 Fc Heterodimer combYSelect2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain | Authors: | Azzam, T, Du, J.J, Sundberg, E.J. | Deposit date: | 2023-08-16 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers. Sci Adv, 10, 2024
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8U47
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8U48
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![BU of 8u48 by Molmil](/molmil-images/mine/8u48) | Crystal structure of Bacteroides thetaiotamicron BT1285 D161A-E163A inactive Endoglycosidase in complex with high-mannose N-glycan (Man9GlcNAc2) substrate | Descriptor: | Endo-beta-N-acetylglucosaminidase, PHOSPHATE ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Sastre, D.E, Sultana, N, Navarro, M.V.A.S, Sundberg, E.J. | Deposit date: | 2023-09-09 | Release date: | 2024-05-29 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate. Nat Commun, 15, 2024
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8U46
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8U9F
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![BU of 8u9f by Molmil](/molmil-images/mine/8u9f) | Crystal structure of Bacteroides thetaiotamicron BT1285 in complex with NaI | Descriptor: | 1,2-ETHANEDIOL, Endo-beta-N-acetylglucosaminidase, IODIDE ION, ... | Authors: | Sastre, D.E, Navarro, M.V.A.S, Sundberg, E.J. | Deposit date: | 2023-09-19 | Release date: | 2024-05-29 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate. Nat Commun, 15, 2024
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6T8K
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![BU of 6t8k by Molmil](/molmil-images/mine/6t8k) | Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with Man9GlcNAc product in P1 | Descriptor: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase F1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E. | Deposit date: | 2019-10-24 | Release date: | 2020-02-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. Nat Commun, 11, 2020
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6TCV
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![BU of 6tcv by Molmil](/molmil-images/mine/6tcv) | Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with Man9GlcNAc2Asn substrate | Descriptor: | ASPARAGINE, Endo-beta-N-acetylglucosaminidase F1, GLYCEROL, ... | Authors: | Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E. | Deposit date: | 2019-11-06 | Release date: | 2020-02-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.311 Å) | Cite: | Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. Nat Commun, 11, 2020
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6T8I
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![BU of 6t8i by Molmil](/molmil-images/mine/6t8i) | Crystal structure of wild type EndoBT-3987 from Bacteroides thetaiotamicron VPI-5482 | Descriptor: | Endo-beta-N-acetylglucosaminidase F1, GLYCEROL | Authors: | Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E. | Deposit date: | 2019-10-24 | Release date: | 2020-02-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. Nat Commun, 11, 2020
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6T8L
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![BU of 6t8l by Molmil](/molmil-images/mine/6t8l) | Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 with Man9GlcNAc product in P212121 | Descriptor: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase F1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E. | Deposit date: | 2019-10-24 | Release date: | 2020-02-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. Nat Commun, 11, 2020
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6TCW
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![BU of 6tcw by Molmil](/molmil-images/mine/6tcw) | Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 with Man5GlcNAc product | Descriptor: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase F1, GLYCEROL, ... | Authors: | Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E. | Deposit date: | 2019-11-06 | Release date: | 2020-02-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides. Nat Commun, 11, 2020
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1T7E
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![BU of 1t7e by Molmil](/molmil-images/mine/1t7e) | Crystal structure of mutant Pro9Ser of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | Descriptor: | Alpha-like neurotoxin BmK-I, PHOSPHATE ION | Authors: | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | Deposit date: | 2004-05-09 | Release date: | 2004-09-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins J.Mol.Biol., 341, 2004
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8UWV
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![BU of 8uwv by Molmil](/molmil-images/mine/8uwv) | |
5VB0
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![BU of 5vb0 by Molmil](/molmil-images/mine/5vb0) | Crystal structure of fosfomycin resistance protein FosA3 | Descriptor: | Fosfomycin resistance protein FosA3, MANGANESE (II) ION, NICKEL (II) ION | Authors: | Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E. | Deposit date: | 2017-03-28 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.689 Å) | Cite: | Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli. Antimicrob. Agents Chemother., 61, 2017
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5V91
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![BU of 5v91 by Molmil](/molmil-images/mine/5v91) | Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae | Descriptor: | Fosfomycin resistance protein, ZINC ION | Authors: | Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E. | Deposit date: | 2017-03-22 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli. Antimicrob. Agents Chemother., 61, 2017
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5V3D
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![BU of 5v3d by Molmil](/molmil-images/mine/5v3d) | Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae with bound fosfomycin | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FOSFOMYCIN, ... | Authors: | Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E. | Deposit date: | 2017-03-07 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.539 Å) | Cite: | Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli. Antimicrob. Agents Chemother., 61, 2017
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7LF9
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![BU of 7lf9 by Molmil](/molmil-images/mine/7lf9) | Structure of Hyperglycosylated Human IgG1 Fc (Fc329) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc (Fc329), ... | Authors: | Fields, J.K, Sundberg, E.J. | Deposit date: | 2021-01-15 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions To Be Published
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7LF5
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![BU of 7lf5 by Molmil](/molmil-images/mine/7lf5) | Structure of Hyperglycosylated Human IgG1 Fc (Fc267) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc (Fc267), alpha-L-fucopyranose, ... | Authors: | Fields, J.K, Sundberg, E.J. | Deposit date: | 2021-01-15 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions To Be Published
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7LBL
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![BU of 7lbl by Molmil](/molmil-images/mine/7lbl) | Structure of Human IgG1 Fc | Descriptor: | Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Fields, J.K, Sundberg, E.J. | Deposit date: | 2021-01-08 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions To Be Published
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6AW0
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![BU of 6aw0 by Molmil](/molmil-images/mine/6aw0) | Crystal structure of CEACAM3 L44Q | Descriptor: | CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, GLYCEROL, ... | Authors: | Bonsor, D.A, Sundberg, E.J. | Deposit date: | 2017-09-05 | Release date: | 2018-05-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA. EMBO J., 37, 2018
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