7LBL

Structure of Human IgG1 Fc

Summary for 7LBL

• Entry DOI: 10.2210/pdb7lbl/pdb
• Descriptor: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: effector, igg, antibody, fc, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 55682.39

Authors

Fields, J.K.,Sundberg, E.J. (deposition date: 2021-01-08, release date: 2021-01-20, Last modification date: 2023-10-18)

• Primary citation: Fields, J.K.,Sundberg, E.J.; Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.13 Å)