8VFU

The Fab Crystal Structure of the PAN IL-1 Family Inhibitor Antibody 3G5

Summary for 8VFU

• Entry DOI: 10.2210/pdb8vfu/pdb
• Descriptor: 3G5 Light Chain, 3G5 Heavy Chain (3 entities in total)
• Functional Keywords: fab, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 48501.95

Authors

Fields, J.K.,Sundberg, E.J. (deposition date: 2023-12-22, release date: 2024-02-21)

• Primary citation: Fields, J.K.,Sundberg, E.J.; Antibodies targeting the shared cytokine receptor IL-1 Receptor Accessory Protein (IL-1RAcP) invoke distinct mechanisms to block signaling by IL-1RAcP dependent cytokines; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.45 Å)