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PDB: 108 件
2NTS
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Crystal Structure of SEK-hVb5.1
分子名称: Staphylococcal enterotoxin K, TRBC1 protein
著者Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J.
登録日2006-11-08
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A novel loop domain in superantigens extends their T cell receptor recognition site
J.Mol.Biol., 371, 2007
8A64
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cryoEM structure of the catalytically inactive EndoS from S. pyogenes in complex with the Fc region of immunoglobulin G1.
分子名称: Endo-beta-N-acetylglucosaminidase F2, Immunoglobulin gamma-1 heavy chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Trastoy, B, Cifuente, J.O, Du, J.J, Sundberg, E.J, Guerin, M.E.
登録日2022-06-16
公開日2023-04-05
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases.
Nat Commun, 14, 2023
3MFG
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BU of 3mfg by Molmil
Crystal structure of Toxic Shock Syndrome Toxin 1 (TSST-1) in complex with the human T cell receptor beta chain Vbeta2.1 (EP-8)
分子名称: GLYCEROL, SULFATE ION, Toxic shock syndrome toxin-1, ...
著者Bonsor, D.A, Sundberg, E.J.
登録日2010-04-02
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Crystal structure of Toxic Shock Syndrome Toxin 1 (TSST-1) in complex with the human T cell receptor beta chain Vbeta2.1 (EP-8)
To be Published
8VFU
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BU of 8vfu by Molmil
The Fab Crystal Structure of the PAN IL-1 Family Inhibitor Antibody 3G5
分子名称: 3G5 Heavy Chain, 3G5 Light Chain
著者Fields, J.K, Sundberg, E.J.
登録日2023-12-22
公開日2024-02-21
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling.
Cell Rep, 43, 2024
4IZE
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BU of 4ize by Molmil
Crystal Structure of IL-36gamma
分子名称: Interleukin-36 gamma
著者Guenther, S, Sundberg, E.J.
登録日2013-01-29
公開日2014-06-25
最終更新日2014-07-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor.
J.Immunol., 193, 2014
8TTM
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BU of 8ttm by Molmil
IgG1 Fc Heterodimer combYSelect1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain
著者Azzam, T, Du, J.J, Sundberg, E.J.
登録日2023-08-14
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers.
Sci Adv, 10, 2024
8TUD
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IgG1 Fc Heterodimer combYSelect2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain
著者Azzam, T, Du, J.J, Sundberg, E.J.
登録日2023-08-16
公開日2024-06-26
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers.
Sci Adv, 10, 2024
8U47
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Crystal structure of Bacteroides thetaiotaomicron VPI-5482 Endoglycosidase BT1285
分子名称: Endo-beta-N-acetylglucosaminidase, MAGNESIUM ION, PHOSPHATE ION
著者Sastre, D.E, Sultana, N, Sundberg, E.J.
登録日2023-09-09
公開日2024-05-29
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.
Nat Commun, 15, 2024
8U48
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Crystal structure of Bacteroides thetaiotamicron BT1285 D161A-E163A inactive Endoglycosidase in complex with high-mannose N-glycan (Man9GlcNAc2) substrate
分子名称: Endo-beta-N-acetylglucosaminidase, PHOSPHATE ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Sastre, D.E, Sultana, N, Navarro, M.V.A.S, Sundberg, E.J.
登録日2023-09-09
公開日2024-05-29
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.
Nat Commun, 15, 2024
8U46
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Crystal structure of Bacteroides thetaiotaomicron VPI-5482 Endoglycosidase BT1285 D161A-E163A inactive version
分子名称: Endo-beta-N-acetylglucosaminidase
著者Sastre, D.E, Sultana, N, Sundberg, E.J.
登録日2023-09-09
公開日2024-05-29
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.
Nat Commun, 15, 2024
8U9F
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Crystal structure of Bacteroides thetaiotamicron BT1285 in complex with NaI
分子名称: 1,2-ETHANEDIOL, Endo-beta-N-acetylglucosaminidase, IODIDE ION, ...
著者Sastre, D.E, Navarro, M.V.A.S, Sundberg, E.J.
登録日2023-09-19
公開日2024-05-29
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.
Nat Commun, 15, 2024
6T8K
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BU of 6t8k by Molmil
Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with Man9GlcNAc product in P1
分子名称: CALCIUM ION, Endo-beta-N-acetylglucosaminidase F1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E.
登録日2019-10-24
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides.
Nat Commun, 11, 2020
6TCV
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BU of 6tcv by Molmil
Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with Man9GlcNAc2Asn substrate
分子名称: ASPARAGINE, Endo-beta-N-acetylglucosaminidase F1, GLYCEROL, ...
著者Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E.
登録日2019-11-06
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.311 Å)
主引用文献Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides.
Nat Commun, 11, 2020
6T8I
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Crystal structure of wild type EndoBT-3987 from Bacteroides thetaiotamicron VPI-5482
分子名称: Endo-beta-N-acetylglucosaminidase F1, GLYCEROL
著者Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E.
登録日2019-10-24
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides.
Nat Commun, 11, 2020
6T8L
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BU of 6t8l by Molmil
Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 with Man9GlcNAc product in P212121
分子名称: CALCIUM ION, Endo-beta-N-acetylglucosaminidase F1, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E.
登録日2019-10-24
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides.
Nat Commun, 11, 2020
6TCW
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BU of 6tcw by Molmil
Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 with Man5GlcNAc product
分子名称: CALCIUM ION, Endo-beta-N-acetylglucosaminidase F1, GLYCEROL, ...
著者Trastoy, B, Du, J.J, Klontz, E.H, Cifuente, J.O, Sundberg, E.J, Guerin, M.E.
登録日2019-11-06
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides.
Nat Commun, 11, 2020
1T7E
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BU of 1t7e by Molmil
Crystal structure of mutant Pro9Ser of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch
分子名称: Alpha-like neurotoxin BmK-I, PHOSPHATE ION
著者Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C.
登録日2004-05-09
公開日2004-09-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
8UWV
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BU of 8uwv by Molmil
Crystal structure of BT3984 SusD-like from Bacteroides thetaiotaomicron VPI-5482 at 1.1 A resolution (Space group P21)
分子名称: BT3984 SusD-like, MAGNESIUM ION
著者Sastre, D.E, Navarro, M.V.A.S, Sundberg, E.J.
登録日2023-11-08
公開日2023-11-22
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Crystal structure of BT3984 SusD-like from Bacteroides thetaiotaomicron VPI-5482 at 1.1 A resolution (Space group P21)
To Be Published
5VB0
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BU of 5vb0 by Molmil
Crystal structure of fosfomycin resistance protein FosA3
分子名称: Fosfomycin resistance protein FosA3, MANGANESE (II) ION, NICKEL (II) ION
著者Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E.
登録日2017-03-28
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.689 Å)
主引用文献Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli.
Antimicrob. Agents Chemother., 61, 2017
5V91
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Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae
分子名称: Fosfomycin resistance protein, ZINC ION
著者Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E.
登録日2017-03-22
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli.
Antimicrob. Agents Chemother., 61, 2017
5V3D
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BU of 5v3d by Molmil
Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae with bound fosfomycin
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FOSFOMYCIN, ...
著者Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E.
登録日2017-03-07
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.539 Å)
主引用文献Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli.
Antimicrob. Agents Chemother., 61, 2017
7LF9
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BU of 7lf9 by Molmil
Structure of Hyperglycosylated Human IgG1 Fc (Fc329)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc (Fc329), ...
著者Fields, J.K, Sundberg, E.J.
登録日2021-01-15
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
To Be Published
7LF5
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BU of 7lf5 by Molmil
Structure of Hyperglycosylated Human IgG1 Fc (Fc267)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc (Fc267), alpha-L-fucopyranose, ...
著者Fields, J.K, Sundberg, E.J.
登録日2021-01-15
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
To Be Published
7LBL
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BU of 7lbl by Molmil
Structure of Human IgG1 Fc
分子名称: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Fields, J.K, Sundberg, E.J.
登録日2021-01-08
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
To Be Published
6AW0
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Crystal structure of CEACAM3 L44Q
分子名称: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, GLYCEROL, ...
著者Bonsor, D.A, Sundberg, E.J.
登録日2017-09-05
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018

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