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PDB: 43 件
1A11
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NMR STRUCTURE OF MEMBRANE SPANNING SEGMENT 2 OF THE ACETYLCHOLINE RECEPTOR IN DPC MICELLES, 10 STRUCTURES
分子名称: ACETYLCHOLINE RECEPTOR M2
著者Gesell, J.J, Sun, W, Montal, M, Opella, S.J.
登録日1997-12-19
公開日1998-04-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy.
Nat.Struct.Biol., 6, 1999
7BZ2
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Cryo-EM structure of the formoterol-bound beta2 adrenergic receptor-Gs protein complex.
分子名称: Beta2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhang, Y.N, Yang, F, Ling, S.L, Lv, P, Zhou, Y.X, Fang, W, Sun, W, Shi, P, Tian, C.L.
登録日2020-04-26
公開日2020-08-05
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Single-particle cryo-EM structural studies of the beta2AR-Gs complex bound with a full agonist formoterol.
Cell Discov, 6, 2020
4IC6
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Crystal structure of Deg8
分子名称: Protease Do-like 8, chloroplastic
著者Gong, W, Sun, W, Fan, H, Gao, F, Liu, L.
登録日2012-12-10
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases
Acta Crystallogr.,Sect.D, 69, 2013
4IC5
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Crystal structure of Deg5
分子名称: CALCIUM ION, Protease Do-like 5, chloroplastic
著者Gong, W, Sun, W, Fan, H, Gao, F, Liu, L.
登録日2012-12-10
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.607 Å)
主引用文献The structures of Arabidopsis Deg5 and Deg8 reveal new insights into HtrA proteases
Acta Crystallogr.,Sect.D, 69, 2013
6LTR
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Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket
分子名称: 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ...
著者Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y.
登録日2020-01-23
公開日2020-10-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
6LU0
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Crystal structure of Cas12i2 ternary complex with 12 nt spacer
分子名称: Cas12i2, DNA (5'-D(*GP*CP*CP*GP*CP*TP*TP*TP*CP*TP*T)-3'), DNA (5'-D(*GP*CP*TP*TP*GP*CP*TP*CP*TP*GP*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*C)-3'), ...
著者Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y.
登録日2020-01-24
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
6LTP
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Crystal structure of Cas12i2 binary complex
分子名称: Cas12i2, crRNA (56-mer RNA)
著者Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y.
登録日2020-01-23
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
6DRJ
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Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, ADPR/Ca2+ bound state
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Transient receptor potential cation channel, ...
著者Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W.
登録日2018-06-12
公開日2018-09-19
最終更新日2018-10-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
Nature, 562, 2018
6DRK
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Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, Apo state
分子名称: Transient receptor potential cation channel, subfamily M, member 2
著者Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W.
登録日2018-06-12
公開日2018-09-19
最終更新日2018-10-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
Nature, 562, 2018
5WP6
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Cryo-EM structure of a human TRPM4 channel in complex with calcium and decavanadate
分子名称: DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
著者Winkler, P.A, Huang, Y, Sun, W, Du, J, Lu, W.
登録日2017-08-03
公開日2017-12-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Electron cryo-microscopy structure of a human TRPM4 channel.
Nature, 552, 2017
8J0H
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Crystal structure of the fission yeast Rex1BD protein(C4H3.06)
分子名称: Uncharacterized protein C4H3.06
著者Li, J, Sun, W, Chen, Y.
登録日2023-04-11
公開日2023-11-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.383 Å)
主引用文献The SUN-family protein Sad1 mediates heterochromatin spatial organization through interaction with histone H2A-H2B.
Nat Commun, 15, 2024
6JDX
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Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin
分子名称: 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.
登録日2019-02-02
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6JDJ
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Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9
分子名称: AcrIIC2, CRISPR-associated endonuclease Cas9
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.
登録日2019-02-01
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6JD7
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Crystal structure of anti-CRISPR protein AcrIIC2 dimer
分子名称: ACETATE ION, AcrIIC2, MAGNESIUM ION
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.L.
登録日2019-01-31
公開日2019-05-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
8GW3
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Crystal structure of human TAK1 kinase domain fused with TAB1
分子名称: Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
著者Liu, J, Sun, W, Gao, J.
登録日2022-09-16
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of human TAK1 kinase domain fused with TAB1
To Be Published
8HJ4
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CryoEM structure of an anti-CRISPR protein AcrIIC5 bound to Nme1Cas9-sgRNA complex
分子名称: CRISPR-associated endonuclease Cas9, Phage protein, sgRNA
著者Wang, Y, Sun, W.
登録日2022-11-22
公開日2023-01-25
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Anti-CRISPR AcrIIC5 is a dsDNA mimic that inhibits type II-C Cas9 effectors by blocking PAM recognition.
Nucleic Acids Res., 51, 2023
7CZ5
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Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex
分子名称: CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
登録日2020-09-07
公開日2020-11-18
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for activation of the growth hormone-releasing hormone receptor.
Nat Commun, 11, 2020
2NR1
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TRANSMEMBRANE SEGMENT 2 OF NMDA RECEPTOR NR1, NMR, 10 STRUCTURES
分子名称: NR1 M2
著者Gesell, J.J, Sun, W, Montal, M, Opella, S.
登録日1997-12-22
公開日1998-04-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy.
Nat.Struct.Biol., 6, 1999
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