8GOE
 
 | | Structure of hSLC19A1+5-MTHF | | Descriptor: | N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, Reduced folate transporter | | Authors: | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | | Deposit date: | 2022-08-24 | | Release date: | 2022-10-05 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022
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1Q8M
 | | Crystal structure of the human myeloid cell activating receptor TREM-1 | | Descriptor: | GLUTATHIONE, SULFATE ION, triggering receptor expressed on myeloid cells 1 | | Authors: | Radaev, S, Kattah, M, Rostro, B, Colonna, M, Sun, P.D. | | Deposit date: | 2003-08-21 | | Release date: | 2003-12-09 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the human myeloid cell activating receptor TREM-1
Structure, 11, 2003
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6C68
 | | MHC-independent t cell receptor A11 | | Descriptor: | T-cell receptor alpha chain, T-cell receptor beta chain | | Authors: | Lu, J, Van Laethem, F, Saba, I, Chu, J, Bhattacharya, A, Love, N.C, Tikhonova, A, Radaev, S, Sun, X, Ko, A, Arnon, T, Shifrut, E, Friedman, N, Weng, N, Singer, A, Sun, P.D. | | Deposit date: | 2018-01-18 | | Release date: | 2019-01-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structure of MHC-Independent TCRs and Their Recognition of Native Antigen CD155.
J Immunol., 204, 2020
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1B6E
 | | HUMAN CD94 | | Descriptor: | CD94 | | Authors: | Boyington, J.C, Riaz, A.N, Patamawenu, A, Coligan, J.E, Brooks, A.G, Sun, P.D. | | Deposit date: | 1999-01-14 | | Release date: | 1999-06-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors.
Immunity, 10, 1999
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3KHQ
 | | Crystal structure of murine Ig-beta (CD79b) in the monomeric form | | Descriptor: | B-cell antigen receptor complex-associated protein beta chain, CITRATE ANION, GLUTATHIONE, ... | | Authors: | Radaev, S, Sun, P.D. | | Deposit date: | 2009-10-30 | | Release date: | 2010-08-25 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
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3KFD
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3KG5
 | | Crystal structure of human Ig-beta homodimer | | Descriptor: | B-cell antigen receptor complex-associated protein beta chain | | Authors: | Radaev, S, Sun, P.D. | | Deposit date: | 2009-10-28 | | Release date: | 2010-08-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
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1KCG
 | | NKG2D in complex with ULBP3 | | Descriptor: | GLUTATHIONE, NKG2-D type II integral membrane protein, ULBP3 protein | | Authors: | Radaev, S, Sun, P. | | Deposit date: | 2001-11-08 | | Release date: | 2002-01-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3.
Immunity, 15, 2001
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1P6F
 | | Structure of the human natural cytotoxicity receptor NKp46 | | Descriptor: | natural cytotoxicity triggering receptor 1 | | Authors: | Foster, C.E, Colonna, M, Sun, P.D. | | Deposit date: | 2003-04-29 | | Release date: | 2003-12-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the human natural killer (NK) cell activating receptor NKp46 reveals structural relationship to other leukocyte receptor complex immunoreceptors.
J.Biol.Chem., 278, 2003
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1T89
 | | CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (HEXAGONAL) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Low affinity immunoglobulin gamma Fc region receptor III-B, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Radaev, S, Motyka, S, Fridman, W.-H, Sautes-Fridman, C, Sun, P.D. | | Deposit date: | 2004-05-11 | | Release date: | 2004-09-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The structure of a human type III Fcgamma receptor in complex with Fc
J.Biol.Chem., 276, 2001
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1T83
 | | CRYSTAL STRUCTURE OF A HUMAN TYPE III FC GAMMA RECEPTOR IN COMPLEX WITH AN FC FRAGMENT OF IGG1 (ORTHORHOMBIC) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, DIBROMOMERCURY, IGG1, ... | | Authors: | Radaev, S, Motyka, S, Fridman, W.-H, Sautes-Fridman, C, Sun, P.D. | | Deposit date: | 2004-05-11 | | Release date: | 2004-09-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The structure of a human type III Fcgamma receptor in complex with Fc
J.Biol.Chem., 276, 2001
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8IKJ
 | | Cryo-EM structure of the inactive CD97 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G protein-coupled receptor E5,Soluble cytochrome b562,Adhesion G protein-coupled receptor E5 subunit beta | | Authors: | Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P, Guo, J, Qin, J, Shen, D, Ji, S, Zang, S, Zhang, H, Wang, W, Shen, Q, Sun, P, Zhang, Y. | | Deposit date: | 2023-02-28 | | Release date: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Conformational transitions and activation of the adhesion receptor CD97.
Mol.Cell, 84, 2024
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6C61
 | | MHC-independent T-cell receptor B12A | | Descriptor: | T-cell receptor alpha chain, T-cell receptor beta chain | | Authors: | Lu, J, Sun, P. | | Deposit date: | 2018-01-17 | | Release date: | 2019-01-30 | | Last modified: | 2020-08-12 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Structure of MHC-Independent TCRs and Their Recognition of Native Antigen CD155.
J Immunol., 204, 2020
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4IP8
 | | Structure of human serum amyloid A1 | | Descriptor: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, SULFATE ION, Serum amyloid A-1 protein | | Authors: | Lu, J, Sun, P.D. | | Deposit date: | 2013-01-09 | | Release date: | 2014-03-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.193 Å) | | Cite: | Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2ZG2
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2ZG3
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2IC1
 | | Crystal Structure of Human Cysteine Dioxygenase in Complex with Substrate Cysteine | | Descriptor: | CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION | | Authors: | Ye, S, Wu, X, Wei, L, Tang, D, Sun, P, Rao, Z. | | Deposit date: | 2006-09-12 | | Release date: | 2006-12-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | An Insight into the Mechanism of Human Cysteine Dioxygenase: KEY ROLES OF THE THIOETHER-BONDED TYROSINE-CYSTEINE COFACTOR.
J.Biol.Chem., 282, 2007
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3NOI
 | | Crystal Structure of Natural Killer Cell Cytotoxicity Receptor NKp30 (NCR3) | | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CALCIUM ION, Natural cytotoxicity triggering receptor 3 | | Authors: | Joyce, M.G, Sun, P.D. | | Deposit date: | 2010-06-25 | | Release date: | 2011-03-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.842 Å) | | Cite: | Structure of the Natural Killer cell activating receptor NKp30 and dissection of ligand binding site
Proc.Natl.Acad.Sci.USA, 2011
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2ZG1
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2LW3
 | | Solution structure of the soluble domain of MmpS4 from Mycobacterium tuberculosis | | Descriptor: | Putative membrane protein mmpS4 | | Authors: | Xi, Z, Sun, P, Wang, W, Lai, C, Wu, F, Tian, C. | | Deposit date: | 2012-07-19 | | Release date: | 2013-03-13 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis
Plos Pathog., 9, 2013
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2MVT
 | | Solution structure of scoloptoxin SSD609 from Scolopendra mutilans | | Descriptor: | Scoloptoxin SSD609 | | Authors: | Wu, F, Sun, P, Wang, C, He, Y, Zhang, L, Tian, C. | | Deposit date: | 2014-10-14 | | Release date: | 2015-09-23 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | A distinct three-helix centipede toxin SSD609 inhibits Iks channels by interacting with the KCNE1 auxiliary subunit.
Sci Rep, 5, 2015
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4PYP
 | | Crystal structure of the human glucose transporter GLUT1 | | Descriptor: | Solute carrier family 2, facilitated glucose transporter member 1, nonyl beta-D-glucopyranoside | | Authors: | Deng, D, Yan, C.Y, Xu, C, Wu, J.P, Sun, P.C, Hu, M.X, Yan, N. | | Deposit date: | 2014-03-27 | | Release date: | 2014-05-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.166 Å) | | Cite: | Crystal structure of the human glucose transporter GLUT1
Nature, 510, 2014
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1M9Z
 | | CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN | | Descriptor: | GLYCEROL, TGF-BETA RECEPTOR TYPE II | | Authors: | Boesen, C.C, Radaev, S, Motyka, S.A, Patamawenu, A, Sun, P.D. | | Deposit date: | 2002-07-30 | | Release date: | 2002-09-11 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | THE 1.1A CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN
Structure, 10, 2002
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4IP9
 | | Structure of native human serum amyloid A1 | | Descriptor: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Serum amyloid A-1 protein | | Authors: | Lu, J, Sun, P.D. | | Deposit date: | 2013-01-09 | | Release date: | 2014-03-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proc.Natl.Acad.Sci.USA, 111, 2014
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8GRD
 | | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ... | | Authors: | Chen, X, Sun, P, Ding, J. | | Deposit date: | 2022-09-01 | | Release date: | 2022-11-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.699 Å) | | Cite: | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
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