4DFB
 
 | | Crystal structure of aminoglycoside phosphotransferase aph(2")-id/aph(2")-iva in complex with kanamycin | | 分子名称: | APH(2")-Id, CHLORIDE ION, KANAMYCIN A | | 著者 | Stogios, P.J, Minasov, G, Osipiuk, J, Evdokimova, E, Egorova, E, Di leo, R, Li, H, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-01-23 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A small molecule discrimination map of the antibiotic resistance kinome.
Chem.Biol., 18, 2011
|
|
4DBX
 | | Crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA | | 分子名称: | APH(2")-ID | | 著者 | Stogios, P.J, Minasov, G, Tan, K, Nocek, B, Singer, A.U, Evdokimova, E, Egorova, E, Di Leo, R, Li, H, Shakya, T, Wright, G.D, Savchenko, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2012-01-16 | | 公開日 | 2012-02-01 | | 最終更新日 | 2012-04-25 | | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | | 主引用文献 | A small molecule discrimination map of the antibiotic resistance kinome.
Chem.Biol., 18, 2011
|
|
4DE4
 | | Crystal structure of aminoglycoside phosphotransferase APH(2")-Id/APH(2")-IVa in complex with HEPES | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, APH(2")-Id | | 著者 | Stogios, P.J, Minasov, G, Tan, K, Nocek, B, Evdokimova, E, Egorova, O, Di Leo, R, Li, H, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-01-19 | | 公開日 | 2012-02-08 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A small molecule discrimination map of the antibiotic resistance kinome.
Chem.Biol., 18, 2011
|
|
4H59
 | | Crystal structure of iron uptake ABC transporter substrate-binding protein PiaA from Streptococcus pneumoniae Canada MDR_19A bound to Bis-tris propane | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Stogios, P.J, Wawrzak, Z, Kudritska, M, Minasov, G, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-09-18 | | 公開日 | 2012-10-03 | | 最終更新日 | 2016-05-04 | | 実験手法 | X-RAY DIFFRACTION (1.658 Å) | | 主引用文献 | Crystal structure of iron uptake ABC transporter substrate-binding protein PiaA from Streptococcus pneumoniae Canada MDR_19A bound to Bis-tris propane
To be Published
|
|
4DFU
 | | Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, APH(2")-Id, CHLORIDE ION, ... | | 著者 | Stogios, P.J, Minasov, G, Dong, A, Evdokimova, E, Egorova, E, Di Leo, R, Li, H, Shakya, T, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-01-24 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | A small molecule discrimination map of the antibiotic resistance kinome.
Chem.Biol., 18, 2011
|
|
4I62
 | | 1.05 Angstrom crystal structure of an amino acid ABC transporter substrate-binding protein AbpA from Streptococcus pneumoniae Canada MDR_19A bound to L-arginine | | 分子名称: | ARGININE, Amino acid ABC transporter, periplasmic amino acid-binding protein, ... | | 著者 | Stogios, P.J, Kudritska, M, Wawrzak, Z, Minasov, G, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-11-29 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | 1.05 Angstrom crystal structure of an amino acid ABC transporter substrate-binding protein from Streptococcus pneumoniae Canada MDR_19A bound to L-arginine
To be Published
|
|
6D2X
 | | Crystal structure of the GH26 domain from PbGH26-GH5A endo-beta-mannanase/endo-beta-glucanase from Prevotella bryantii | | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Aryl-phospho-beta-D-glucosidase BglC, GH1 family, ... | | 著者 | Stogios, P.J, Skarina, T, McGregor, N, Di Leo, R, Brumer, H, Savchenko, A. | | 登録日 | 2018-04-14 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Crystal structure of the GH26 domain from PbGH26-GH5A endo-beta-mannanase/endo-beta-glucanase from Prevotella bryantii
To Be Published
|
|
6D2Y
 | | Crystal structure of surface glycan-binding protein PbSGBP-B from Prevotella bryantii | | 分子名称: | GLYCEROL, MAGNESIUM ION, PbSGBP-B lipoprotein | | 著者 | Stogios, P.J, Skarina, T, Wawrzak, Z, McGregor, N, Di Leo, R, Brumer, H, Savchenko, A. | | 登録日 | 2018-04-14 | | 公開日 | 2019-10-16 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal structure of surface glycan-binding protein PbSGBP-B from Prevotella bryantii
To Be Published
|
|
6D2W
 | | Crystal structure of Prevotella bryantii endo-beta-mannanase/endo-beta-glucanase PbGH26A-GH5A | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aryl-phospho-beta-D-glucosidase BglC, GH1 family, ... | | 著者 | Stogios, P.J, Skarina, T, McGregor, N, Nocek, B, Di Leo, R, Brumer, H, Savchenko, A. | | 登録日 | 2018-04-14 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of Prevotella bryantii endo-beta-mannanase/endo-beta-glucanase PbGH26A-GH5A
To Be Published
|
|
5IR0
 | | Crystal structure of protein of unknown function ORF19 from Vibrio cholerae O1 PICI-like element, C57S I109M mutant | | 分子名称: | CITRIC ACID, Uncharacterized protein ORF19 | | 著者 | Stogios, P.J, Wawrzak, Z, Skarina, T, Di Leo, R, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2016-03-11 | | 公開日 | 2016-03-30 | | 実験手法 | X-RAY DIFFRACTION (3.297 Å) | | 主引用文献 | Crystal structure of protein of unknown function ORF19 from Vibrio cholerae O1 PICI-like element, C57S I109M mutant
To Be Published
|
|
6DM3
 | | Crystal structure of the SH2 domain from RavO (Lpg1129) from Legionella pneumophila, apoprotein | | 分子名称: | RavO | | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Kaneko, T, Li, S, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2018-06-04 | | 公開日 | 2018-06-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of the SH2 domain from RavO (Lpg1129) from Legionella pneumophila, apoprotein
To Be Published
|
|
7S8K
 | | Crystal structure of a GH12-2 family cellulase from Thermococcus sp. 2319x1 | | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Stogios, P.J, Skarina, T, Khusnutdinova, A, Yakunin, A.F, Savchenko, A. | | 登録日 | 2021-09-18 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | GH12-2 family cellulase
To Be Published
|
|
5D9M
 | | Crystal structure of PbGH5A, a glycoside hydrolase family 5 enzyme from Prevotella bryantii B14, E280A mutant in complex with the xyloglucan tetradecasaccharide XXXGXXXG | | 分子名称: | B-1,4-endoglucanase, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Morar, M, Stogios, P.J, Xu, X, Cui, H, Di Leo, R, Yim, V, Savchenko, A. | | 登録日 | 2015-08-18 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-Function Analysis of a Mixed-linkage beta-Glucanase/Xyloglucanase from the Key Ruminal Bacteroidetes Prevotella bryantii B14.
J.Biol.Chem., 291, 2016
|
|
5D9P
 | | Crystal structure of PbGH5A, a glycoside hydrolase family 5 enzyme from Prevotella bryantii B14, in complex with an inhibitory N-bromoacetylglycosylamine derivative of XXXG | | 分子名称: | B-1,4-endoglucanase, CALCIUM ION, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-N-acetyl-beta-D-glucopyranosylamine | | 著者 | Morar, M, Stogios, P.J, Xu, X, Cui, H, Di Leo, R, Yim, V, Savchenko, A. | | 登録日 | 2015-08-18 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-Function Analysis of a Mixed-linkage beta-Glucanase/Xyloglucanase from the Key Ruminal Bacteroidetes Prevotella bryantii B14.
J.Biol.Chem., 291, 2016
|
|
5D9O
 | | Crystal structure of PbGH5A, a glycoside hydrolase family 5 enzyme from Prevotella bryantii B14, E280A mutant in complex with cellotetraose | | 分子名称: | B-1,4-endoglucanase, CALCIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Morar, M, Stogios, P.J, Xu, X, Cui, H, Di Leo, R, Yim, V, Savchenko, A. | | 登録日 | 2015-08-18 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure-Function Analysis of a Mixed-linkage beta-Glucanase/Xyloglucanase from the Key Ruminal Bacteroidetes Prevotella bryantii B14.
J.Biol.Chem., 291, 2016
|
|
8CRV
 | | Crystal Structure of the Carbamate Kinase from Pseudomonas aeruginosa | | 分子名称: | 1,2-ETHANEDIOL, Carbamate kinase, FORMIC ACID, ... | | 著者 | Kim, Y, Skarina, T, Mesa, N, Stogios, P, Savchenko, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-05-11 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of the Carbamate Kinase from Pseudomonas aeruginosa
To Be Published
|
|
7SNU
 | | Crystal structure of ShHTL7 from Striga hermonthica in complex with strigolactone antagonist RG6 | | 分子名称: | 2-{(2S)-1-[(4-ethoxyphenyl)methyl]-4-[(2E)-3-(4-methoxyphenyl)prop-2-en-1-yl]piperazin-2-yl}ethan-1-ol, ACETATE ION, GLYCEROL, ... | | 著者 | Arellano-Saab, A, Stogios, P.J, Skarina, T, Yim, V, Savchenko, A, McCourt, P. | | 登録日 | 2021-10-28 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | A novel strigolactone receptor antagonist provides insights into the structural inhibition, conditioning, and germination of the crop parasite Striga.
J.Biol.Chem., 298, 2022
|
|
4RO3
 | | 1.8 Angstrom Crystal Structure of the N-terminal Domain of Protein with Unknown Function from Vibrio cholerae. | | 分子名称: | Hypothetical Protein, SULFATE ION | | 著者 | Minasov, G, Wawrzak, Z, Stogios, P.J, Skarina, T, Seed, K.D, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-10-27 | | 公開日 | 2014-12-03 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | 1.8 Angstrom Crystal Structure of the N-terminal Domain of Protein with Unknown Function from Vibrio cholerae.
To be Published
|
|
5D9N
 | | Crystal structure of PbGH5A, a glycoside hydrolase family 5 member from Prevotella bryantii B14, in complex with the xyloglucan heptasaccharide XXXG | | 分子名称: | B-1,4-endoglucanase, CALCIUM ION, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Morar, M, Stogios, P.J, Xu, X, Cui, H, Di Leo, R, Yim, V, Savchenko, A. | | 登録日 | 2015-08-18 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure-Function Analysis of a Mixed-linkage beta-Glucanase/Xyloglucanase from the Key Ruminal Bacteroidetes Prevotella bryantii B14.
J.Biol.Chem., 291, 2016
|
|
6W75
 | | 1.95 Angstrom Resolution Crystal Structure of NSP10 - NSP16 Complex from SARS-CoV-2 | | 分子名称: | 2'-O-methyltransferase, FORMIC ACID, Non-structural protein 10, ... | | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Wiersum, G, Godzik, A, Jaroszewski, L, Stogios, P.J, Skarina, T, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-03-18 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.
Sci.Signal., 13, 2020
|
|
5VQB
 | | Crystal structure of rifampin monooxygenase from Streptomyces venezuelae, complex with FAD | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Cox, G, Kelso, J, Stogios, P.J, Savchenko, A, Anderson, W.F, Wright, G.D, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-05-08 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.391 Å) | | 主引用文献 | Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action.
Cell Chem Biol, 25, 2018
|
|
8DVC
 | | Receptor ShHTL5 from Striga hermonthica in complex with strigolactone agonist GR24 | | 分子名称: | (3R,3aR,8bS)-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methyl)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Arellano-Saab, A, Skarina, T, Yim, V, Savchenko, A, Stogios, P.J, McCourt, P. | | 登録日 | 2022-07-28 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.638 Å) | | 主引用文献 | Structural analysis of a hormone-bound Striga strigolactone receptor.
Nat.Plants, 9, 2023
|
|
6W4H
 | | 1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex from SARS-CoV-2 | | 分子名称: | 2'-O-methyltransferase, ACETATE ION, Non-structural protein 10, ... | | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Wiersum, G, Godzik, A, Jaroszewski, L, Stogios, P.J, Skarina, T, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-03-10 | | 公開日 | 2020-03-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.
Sci.Signal., 13, 2020
|
|
6OX6
 | | Crystal structure of the complex between the Type VI effector Tas1 and its immunity protein | | 分子名称: | ACETATE ION, PA14_01140, Tas1 | | 著者 | Ahmad, S, Stogios, P.J, Skarina, T, Whitney, J, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2019-05-13 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp.
Nature, 575, 2019
|
|
5F49
 | | Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample in complex with malonyl-coenzyme A | | 分子名称: | COENZYME A, MAGNESIUM ION, MALONYL-COENZYME A, ... | | 著者 | Xu, Z, Skarina, T, Stogios, P.J, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2015-12-03 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes.
ACS Infect Dis, 3, 2017
|
|
