4DFB
Crystal structure of aminoglycoside phosphotransferase aph(2")-id/aph(2")-iva in complex with kanamycin
Replaces: 3R81Summary for 4DFB
Entry DOI | 10.2210/pdb4dfb/pdb |
Related | 4DBX 4DE4 4DFU |
Descriptor | APH(2")-Id, KANAMYCIN A, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | structural genomics, center for structural genomics of infectious diseases, csgid, eukaryotic protein kinase-like fold, aminoglycoside phosphotransferase, kinase, transferase, aminoglycosides, kanamycin, antibiotic, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Enterococcus casseliflavus |
Total number of polymer chains | 2 |
Total formula weight | 77597.98 |
Authors | Stogios, P.J.,Minasov, G.,Osipiuk, J.,Evdokimova, E.,Egorova, E.,Di leo, R.,Li, H.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-01-23, release date: 2012-02-08, Last modification date: 2024-03-13) |
Primary citation | Shakya, T.,Stogios, P.J.,Waglechner, N.,Evdokimova, E.,Ejim, L.,Blanchard, J.E.,McArthur, A.G.,Savchenko, A.,Wright, G.D. A small molecule discrimination map of the antibiotic resistance kinome. Chem.Biol., 18:1591-1601, 2011 Cited by PubMed: 22195561DOI: 10.1016/j.chembiol.2011.10.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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