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PDB: 283 件
1CSL
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CRYSTAL STRUCTURE OF THE RRE HIGH AFFINITY SITE
分子名称: 5'-R(*AP*AP*CP*GP*GP*GP*CP*GP*CP*AP*GP*AP*A)-3', 5'-R(*UP*CP*UP*GP*AP*CP*GP*GP*UP*AP*CP*GP*UP*UP*U)-3'
著者Ippolito, J.A, Steitz, T.A.
登録日1999-08-18
公開日2000-02-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution.
J.Mol.Biol., 295, 2000
1B8H
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SLIDING CLAMP, DNA POLYMERASE
分子名称: DNA POLYMERASE PROCESSIVITY COMPONENT, DNA POLYMERASE fragment
著者Shamoo, Y, Steitz, T.A.
登録日1999-02-01
公開日1999-02-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex.
Cell(Cambridge,Mass.), 99, 1999
1B77
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BUILDING A REPLISOME STRUCTURE FROM INTERACTING PIECES: A SLIDING CLAMP COMPLEXED WITH AN INTERACTION PEPTIDE FROM DNA POLYMERASE
分子名称: PROTEIN (SLIDING CLAMP)
著者Shamoo, Y, Steitz, T.A.
登録日1999-01-27
公開日1999-02-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex.
Cell(Cambridge,Mass.), 99, 1999
1BDN
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CRYSTAL LATTICE PACKING IS IMPORTANT IN DETERMINING THE BEND OF A DNA DODECAMER CONTAINING AN ADENINE TRACT
分子名称: DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*TP*TP*TP*TP*GP*CP*G)-3'), MAGNESIUM ION
著者DiGabriele, A.D, Sanderson, M.R, Steitz, T.A.
登録日1989-07-25
公開日1991-04-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal lattice packing is important in determining the bend of a DNA dodecamer containing an adenine tract.
Proc.Natl.Acad.Sci.USA, 86, 1989
3CME
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BU of 3cme by Molmil
The Structure of CA and CCA-PHE-CAP-BIO Bound to the Large Ribosomal Subunit of Haloarcula Marismortui
分子名称: 50S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Simonovic, M, Steitz, T.A.
登録日2008-03-21
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
1M90
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Co-crystal structure of CCA-Phe-caproic acid-biotin and sparsomycin bound to the 50S ribosomal subunit
分子名称: 23S RRNA, 5S RRNA, 6-AMINOHEXANOIC ACID, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2002-07-26
公開日2002-09-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into peptide bond formation.
Proc.Natl.Acad.Sci.USA, 99, 2002
3CPW
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The structure of the antibiotic LINEZOLID bound to the large ribosomal subunit of HALOARCULA MARISMORTUI
分子名称: 23S RIBOSOMAL RNA, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S ribosomal protein L10E, ...
著者Ippolito, J.A, Kanyo, Z.K, Wang, D, Franceschi, F.J, Moore, P.B, Steitz, T.A, Duffy, E.M.
登録日2008-04-01
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
J.Med.Chem., 51, 2008
1KQS
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The Haloarcula marismortui 50S Complexed with a Pretranslocational Intermediate in Protein Synthesis
分子名称: 23S RRNA, 5S RRNA, 6-AMINOHEXANOIC ACID, ...
著者Schmeing, T.M, Seila, A.C, Hansen, J.L, Freeborn, B, Soukup, J.K, Scaringe, S.A, Strobel, S.A, Moore, P.B, Steitz, T.A.
登録日2002-01-07
公開日2002-02-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits.
Nat.Struct.Biol., 9, 2002
1S72
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REFINED CRYSTAL STRUCTURE OF THE HALOARCULA MARISMORTUI LARGE RIBOSOMAL SUBUNIT AT 2.4 ANGSTROM RESOLUTION
分子名称: 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L11P, ...
著者Klein, D.J, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2004-01-28
公開日2004-06-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Roles of Ribosomal Proteins in the Structure, Assembly and Evolution of the Large Ribosomal Subunit
J.Mol.Biol., 340, 2004
1QC0
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CRYSTAL STRUCTURE OF A 19 BASE PAIR COPY CONTROL RELATED RNA DUPLEX
分子名称: 5'-R(*GP*CP*AP*CP*CP*GP*CP*UP*AP*CP*CP*AP*AP*CP*GP*GP*UP*GP*C)-3', 5'-R(*GP*CP*AP*CP*CP*GP*UP*UP*GP*GP*UP*AP*GP*CP*GP*GP*UP*GP*C)-3', 5'-R(*UP*AP*GP*CP*GP*GP*UP*GP*C)-3', ...
著者Klosterman, P.S, Shah, S.A, Steitz, T.A.
登録日1999-05-17
公開日1999-11-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of two plasmid copy control related RNA duplexes: An 18 base pair duplex at 1.20 A resolution and a 19 base pair duplex at 1.55 A resolution.
Biochemistry, 38, 1999
1QCU
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CRYSTAL STRUCTURE OF AN 18 BASE PAIR COPY CONTROL RELATED RNA DUPLEX
分子名称: 5'-R(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3', 5'-R(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3', AMMONIUM ION
著者Klosterman, P.S, Shah, S.A, Steitz, T.A.
登録日1999-05-14
公開日1999-11-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structures of two plasmid copy control related RNA duplexes: An 18 base pair duplex at 1.20 A resolution and a 19 base pair duplex at 1.55 A resolution.
Biochemistry, 38, 1999
1VY4
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Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing acylated tRNA-substrates in the A and P sites.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Steitz, T.A, Innis, C.A.
登録日2014-05-13
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VY7
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Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Cytidine-Puromycin in the A site and acylated tRNA in the P site.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Steitz, T.A, Innis, C.A.
登録日2014-05-13
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VY5
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Crystal structure of the Thermus thermophilus 70S ribosome in the post-catalysis state of peptide bond formation containing dipeptydil-tRNA in the A site and deacylated tRNA in the P site.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Steitz, T.A, Innis, C.A.
登録日2014-05-13
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1GTS
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BU of 1gts by Molmil
STRUCTURAL BASIS FOR TRANSFER RNA AMINOACEYLATION BY ESCHERICHIA COLI GLUTAMINYL-TRNA SYNTHETASE
分子名称: ADENOSINE MONOPHOSPHATE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18)), TRNAGLN
著者Perona, J.J, Steitz, T.A, Rould, M.A.
登録日1993-09-15
公開日1995-02-07
最終更新日2017-02-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-tRNA synthetase.
Biochemistry, 32, 1993
1VY6
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Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Steitz, T.A, Innis, C.A.
登録日2014-05-13
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1KRP
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DNA polymerase I Klenow fragment (E.C.2.7.7.7) mutant/DNA complex
分子名称: DNA (5'-D(P*TP*TP*PST)-3'), PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), ZINC ION
著者Brautigam, C.A, Steitz, T.A.
登録日1997-08-19
公開日1998-02-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.
J.Mol.Biol., 277, 1998
1KSP
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DNA polymerase I Klenow fragment (E.C.2.7.7.7) mutant/DNA complex
分子名称: DNA (5'-D(P*TP*TP*PST)-3'), PROTEIN (DNA POLYMERASE I-KLENOW FRAGMENT (E.C.2.7.7.7)), ZINC ION
著者Brautigam, C.A, Steitz, T.A.
登録日1997-08-19
公開日1998-02-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.
J.Mol.Biol., 277, 1998
1KFS
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DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX
分子名称: DNA (5'-D(*GP*CP*TP*TP*AP*CP*G)-3'), MAGNESIUM ION, PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), ...
著者Brautigam, C.A, Steitz, T.A.
登録日1997-08-18
公開日1998-02-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.
J.Mol.Biol., 277, 1998
1NOZ
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T4 DNA POLYMERASE FRAGMENT (RESIDUES 1-388) AT 110K
分子名称: DNA POLYMERASE
著者Wang, J, Yu, P, Lin, T.C, Konigsberg, W.H, Steitz, T.A.
登録日1996-02-16
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions.
Biochemistry, 35, 1996
2R6C
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Crystal Form BH2
分子名称: DnaG Primase, Helicase Binding Domain, Replicative helicase
著者Bailey, S, Eliason, W.K, Steitz, T.A.
登録日2007-09-05
公開日2008-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase
Science, 318, 2007
2PYL
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Phi29 DNA polymerase complexed with primer-template DNA and incoming nucleotide substrates (ternary complex)
分子名称: 1,2-ETHANEDIOL, 5'-d(CTGACGAATGTACA)-3', 5'-d(GACTGCTTAC(2DA))-3', ...
著者Berman, A.J, Kamtekar, S, Goodman, J.L, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2007-05-16
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J., 26, 2007
2Q7E
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The structure of pyrrolysyl-tRNA synthetase bound to an ATP analogue
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Kavran, J.M, Steitz, T.A.
登録日2007-06-06
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q7G
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Pyrrolysine tRNA Synthetase bound to a pyrrolysine analogue (cyc) and ATP
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kavran, J.M, Steitz, T.A.
登録日2007-06-06
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R6D
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Crystal Form B1
分子名称: Replicative helicase
著者Bailey, S, Eliason, W.K, Steitz, T.A.
登録日2007-09-05
公開日2008-06-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase
Science, 318, 2007

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