1KFS

DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX

Summary for 1KFS

Entry DOI	10.2210/pdb1kfs/pdb
Descriptor	DNA (5'-D(GPCPTPTPAPCP*G)-3'), PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	complex (hydrolase-dna), exonuclease, phosphorothioate, transferase-dna complex, transferase/dna
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	70527.69
Authors	Brautigam, C.A.,Steitz, T.A. (deposition date: 1997-08-18, release date: 1998-02-25, Last modification date: 2024-04-03)
Primary citation	Brautigam, C.A.,Steitz, T.A. Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates. J.Mol.Biol., 277:363-377, 1998 Cited by PubMed: 9514742 DOI: 10.1006/jmbi.1997.1586 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation