3CPW

The structure of the antibiotic LINEZOLID bound to the large ribosomal subunit of HALOARCULA MARISMORTUI

Summary for 3CPW

Entry DOI	10.2210/pdb3cpw/pdb
Descriptor	23S RIBOSOMAL RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ... (40 entities in total)
Functional Keywords	linezolid, 50s ribosomal subunit, antibiotic complexes, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, metal-binding, zinc-finger, ribosome
Biological source	HALOARCULA MARISMORTUI More
Cellular location	Cytoplasm : P12743
Total number of polymer chains	31
Total formula weight	1474423.98
Authors	Ippolito, J.A.,Kanyo, Z.K.,Wang, D.,Franceschi, F.J.,Moore, P.B.,Steitz, T.A.,Duffy, E.M. (deposition date: 2008-04-01, release date: 2008-07-22, Last modification date: 2024-02-21)
Primary citation	Ippolito, J.A.,Kanyo, Z.K.,Wang, D.,Franceschi, F.J.,Moore, P.B.,Steitz, T.A.,Duffy, E.M. Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit J.Med.Chem., 51:3353-3356, 2008 Cited by PubMed: 18494460 DOI: 10.1021/jm800379d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation