3L89
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3MOR
| Crystal structure of Cathepsin B from Trypanosoma Brucei | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Cathepsin B-like cysteine protease, ... | 著者 | Cupelli, K, Stehle, T. | 登録日 | 2010-04-23 | 公開日 | 2011-11-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | In vivo protein crystallization opens new routes in structural biology. Nat.Methods, 9, 2012
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1VSC
| VCAM-1 | 分子名称: | VASCULAR CELL ADHESION MOLECULE-1 | 著者 | Wang, J, Stehle, T, Osborn, L. | 登録日 | 1995-04-27 | 公開日 | 1996-06-20 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-alpha 4 integrin interaction. Proc.Natl.Acad.Sci.USA, 92, 1995
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8A92
| p53-Y220C Core Domain in Complex with a Bromo-trifluoro-pyrazole-amine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-bromanyl-5-(trifluoromethyl)-1H-pyrazol-3-amine, Cellular tumor antigen p53, ... | 著者 | Stahlecker, J, Braun, M.B, Stehle, T, Boeckler, F.M. | 登録日 | 2022-06-27 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C. Rsc Med Chem, 13, 2022
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7ZIM
| JC Polyomavirus VP1 in complex with 3'-Sialyllactose glycomacromolecules (aromatic linker) | 分子名称: | DI(HYDROXYETHYL)ETHER, Major capsid protein VP1, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ... | 著者 | Freytag, J, Mueller, J.C, Stehle, T. | 登録日 | 2022-04-08 | 公開日 | 2022-12-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Synthesis of Homo- and Heteromultivalent Fucosylated and Sialylated Oligosaccharide Conjugates via Preactivated N -Methyloxyamine Precision Macromolecules and Their Binding to Polyomavirus Capsid Proteins. Biomacromolecules, 23, 2022
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7ZIQ
| BK Polyomavirus VP1 in complex with 6'-Sialyllactose glycomacromolecules (aromatic linker) | 分子名称: | 1,2-ETHANEDIOL, Capsid protein VP1, DI(HYDROXYETHYL)ETHER, ... | 著者 | Freytag, J, Mueller, J.C, Stehle, T. | 登録日 | 2022-04-08 | 公開日 | 2022-12-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Synthesis of Homo- and Heteromultivalent Fucosylated and Sialylated Oligosaccharide Conjugates via Preactivated N -Methyloxyamine Precision Macromolecules and Their Binding to Polyomavirus Capsid Proteins. Biomacromolecules, 23, 2022
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7ZIP
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8AGO
| BK Polyomavirus VP1 mutant E73Q | 分子名称: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | 著者 | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | 登録日 | 2022-07-20 | 公開日 | 2023-02-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.853 Å) | 主引用文献 | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus. Cell Rep, 42, 2023
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8B5B
| Human BRD4 bromdomain 1 in complex with a H4 peptide containing acetyl lysine and ApmTri (H4K5acK8ApmTri) | 分子名称: | Bromodomain-containing protein 4, DI(HYDROXYETHYL)ETHER, H4K5acK8ApmTri | 著者 | Braun, M.B, Bartlick, N, Stehle, T. | 登録日 | 2022-09-22 | 公開日 | 2023-01-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Synthesis, Biochemical Characterization, and Genetic Encoding of a 1,2,4-Triazole Amino Acid as an Acetyllysine Mimic for Bromodomains of the BET Family. Angew.Chem.Int.Ed.Engl., 62, 2023
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4WDZ
| JC Polyomavirus VP1 five-fold pore mutant N221W | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1 | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-09-09 | 公開日 | 2015-02-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Modulation of a Pore in the Capsid of JC Polyomavirus Reduces Infectivity and Prevents Exposure of the Minor Capsid Proteins. J.Virol., 89, 2015
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4X12
| JC Polyomavirus genotype 3 VP1 in complex with GD1b oligosaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X13
| JC Polyomavirus genotype 3 VP1 in complex with LSTc pentasaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X14
| JC Mad-1 polyomavirus VP1 in complex with GM1 oligosaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X0Y
| JC polyomavirus VP1 from a genotype 3 strain | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X15
| JC Mad-1 polyomavirus VP1 in complex with GM2 oligosaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X0Z
| JC Polyomavirus genotype 3 VP1 in complex with GM1 oligosaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X17
| JC Mad-1 polyomavirus VP1 in complex with GD1b oligosaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X11
| JC Polyomavirus genotype 3 VP1 in complex with GD1a oligosaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-05-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X10
| JC Polyomavirus genotype 3 VP1 in complex with GM2 oligosaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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4X16
| JC Mad-1 polyomavirus VP1 in complex with GD1a oligosaccharide | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1, ... | 著者 | Stroh, L.J, Stehle, T. | 登録日 | 2014-11-24 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
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8P1X
| TarM(Se)_G117R-UDP-glucose | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | 著者 | Guo, Y, Stehle, T. | 登録日 | 2023-05-13 | 公開日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition. Sci Adv, 9, 2023
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4E0T
| Crystal structure of CdpNPT in its unbound state | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Cyclic dipeptide N-prenyltransferase, ... | 著者 | Schuller, J.M, Zocher, G, Stehle, T. | 登録日 | 2012-03-05 | 公開日 | 2012-05-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity. J.Mol.Biol., 422, 2012
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2O39
| Human Adenovirus type 11 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) | 分子名称: | CALCIUM ION, Fiber protein, Membrane cofactor protein, ... | 著者 | Persson, D.B, Reiter, D.M, Arnberg, N, Stehle, T. | 登録日 | 2006-12-01 | 公開日 | 2007-01-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Adenovirus type 11 binding alters the conformation of its receptor CD46. Nat.Struct.Mol.Biol., 14, 2007
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7OJ7
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7ZH8
| DYRK1a in Complex with a Bromo-Triazolo-Pyridine | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-bromanyl-3H-[1,2,3]triazolo[4,5-b]pyridine, CHLORIDE ION, ... | 著者 | Dammann, M, Stahlecker, J, Stehle, T, Boeckler, F.M. | 登録日 | 2022-04-05 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes. J.Med.Chem., 65, 2022
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