2O39

Human Adenovirus type 11 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP)

Summary for 2O39

Entry DOI	10.2210/pdb2o39/pdb
Related	1CKL
Descriptor	Fiber protein, Membrane cofactor protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	membrane cofactor protein, mcp, cd46, adenovirus, fiber knob, ad11, virus receptor complex, scr, short consensus repeat, ccp, complement control protein, viral protein-immune system complex, viral protein/immune system
Biological source	Human adenovirus 11p More
Cellular location	Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein: P15529
Total number of polymer chains	4
Total formula weight	74421.51
Authors	Persson, D.B.,Reiter, D.M.,Arnberg, N.,Stehle, T. (deposition date: 2006-12-01, release date: 2007-01-09, Last modification date: 2024-04-03)
Primary citation	Persson, B.D.,Reiter, D.M.,Marttila, M.,Mei, Y.F.,Casasnovas, J.M.,Arnberg, N.,Stehle, T. Adenovirus type 11 binding alters the conformation of its receptor CD46. Nat.Struct.Mol.Biol., 14:164-166, 2007 Cited by PubMed: 17220899 DOI: 10.1038/nsmb1190 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation