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4X14

JC Mad-1 polyomavirus VP1 in complex with GM1 oligosaccharide

Summary for 4X14
Entry DOI10.2210/pdb4x14/pdb
Related3NXD 3NXG
DescriptorMajor capsid protein VP1, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordsbeta-sandwich, jelly-roll, viral major capsid protein, glycan, viral protein
Biological sourceJC polyomavirus (JCPyV)
Cellular locationVirion: P03089
Total number of polymer chains5
Total formula weight154800.80
Authors
Stroh, L.J.,Stehle, T. (deposition date: 2014-11-24, release date: 2015-04-22, Last modification date: 2024-01-10)
Primary citationStroh, L.J.,Maginnis, M.S.,Blaum, B.S.,Nelson, C.D.,Neu, U.,Gee, G.V.,O'Hara, B.A.,Motamedi, N.,DiMaio, D.,Atwood, W.J.,Stehle, T.
The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.
J.Virol., 89:6364-6375, 2015
Cited by
PubMed: 25855729
DOI: 10.1128/JVI.00489-15
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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