4X12

JC Polyomavirus genotype 3 VP1 in complex with GD1b oligosaccharide

Summary for 4X12

• Entry DOI: 10.2210/pdb4x12/pdb
• Related: 3NXG
• Descriptor: Major capsid protein, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, GLYCEROL, ... (6 entities in total)
• Functional Keywords: beta-sandwich, jelly-roll, viral major capsid protein, glycan, viral protein
• Biological source: JC polyomavirus type 3 (JCPyV)
• Total number of polymer chains: 5
• Total formula weight: 154307.60

Authors

Stroh, L.J.,Stehle, T. (deposition date: 2014-11-24, release date: 2015-04-22, Last modification date: 2024-01-10)

• Primary citation: Stroh, L.J.,Maginnis, M.S.,Blaum, B.S.,Nelson, C.D.,Neu, U.,Gee, G.V.,O'Hara, B.A.,Motamedi, N.,DiMaio, D.,Atwood, W.J.,Stehle, T.; The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.; J.Virol., 89:6364-6375, 2015; PubMed: 25855729; DOI: 10.1128/JVI.00489-15

Experimental method

X-RAY DIFFRACTION (1.9 Å)