6MNF
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![BU of 6mnf by Molmil](/molmil-images/mine/6mnf) | Anti-HIV-1 Fab 2G12 + Man8 re-refinement | Descriptor: | Fab 2G12, light chain, Fab 2g12, ... | Authors: | Calarese, D.A, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2018-10-01 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.758 Å) | Cite: | Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc. Natl. Acad. Sci. U.S.A., 102, 2005
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6N35
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![BU of 6n35 by Molmil](/molmil-images/mine/6n35) | Anti-HIV-1 Fab 2G12 + Man1-2 re-refinement | Descriptor: | BENZOIC ACID, Fab 2G12 heavy chain, Fab 2G12 light chain, ... | Authors: | Calarese, D.A, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2018-11-14 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.747 Å) | Cite: | Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science, 300, 2003
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6MU3
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![BU of 6mu3 by Molmil](/molmil-images/mine/6mu3) | Anti-HIV-1 Fab 2G12 + Man7 re-refinement | Descriptor: | Fab 2G12, heavy chain, light chain, ... | Authors: | Wilson, I.A, Calarese, D.A, Stanfield, R.L. | Deposit date: | 2018-10-22 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.327 Å) | Cite: | Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc. Natl. Acad. Sci. U.S.A., 102, 2005
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6O30
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![BU of 6o30 by Molmil](/molmil-images/mine/6o30) | Lipid A transporter MsbA from Salmonella typhimurium | Descriptor: | Lipid A export ATP-binding/permease protein MsbA | Authors: | Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L. | Deposit date: | 2019-02-25 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.47 Å) | Cite: | Structural Insights into the Lipid A Transport Pathway in MsbA. Structure, 27, 2019
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6N32
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![BU of 6n32 by Molmil](/molmil-images/mine/6n32) | Anti-HIV-1 Fab 2G12 re-refinement | Descriptor: | Fab 2G12 heavy chain, Fab 2G12 light chain, SULFATE ION | Authors: | Calarese, D.A, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2018-11-14 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science, 300, 2003
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5VMY
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![BU of 5vmy by Molmil](/molmil-images/mine/5vmy) | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS) | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ... | Authors: | Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2017-04-28 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018
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5UM8
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![BU of 5um8 by Molmil](/molmil-images/mine/5um8) | Crystal structure of HIV-1 envelope trimer 16055 NFL TD CC (T569G) in complex with Fabs 35022 and PGT124 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 35022 heavy chain, ... | Authors: | Garces, F, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2017-01-26 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.935 Å) | Cite: | Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity, 46, 2017
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5W6D
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![BU of 5w6d by Molmil](/molmil-images/mine/5w6d) | Crystal structure of BG505-SOSIP.v4.1-GT1-N137A in complex with Fabs 35022 and 9H/109L | Descriptor: | 109L FAB light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Garces, F, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2017-06-16 | Release date: | 2017-07-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.202 Å) | Cite: | Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. J. Exp. Med., 214, 2017
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5VMW
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![BU of 5vmw by Molmil](/molmil-images/mine/5vmw) | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS) | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ... | Authors: | Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2017-04-28 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018
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8T5X
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![BU of 8t5x by Molmil](/molmil-images/mine/8t5x) | Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T) | Descriptor: | Transthyretin | Authors: | Ferguson, J.A, Sun, X, Leach, B.I, Stanfield, R.L, Dyson, H.J, Wright, P.E. | Deposit date: | 2023-06-14 | Release date: | 2023-08-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant. J.Am.Chem.Soc., 146, 2024
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5VMU
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![BU of 5vmu by Molmil](/molmil-images/mine/5vmu) | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS) | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ... | Authors: | Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2017-04-28 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.346 Å) | Cite: | CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018
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5VMZ
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![BU of 5vmz by Molmil](/molmil-images/mine/5vmz) | Kaiso (ZBTB33) E535Q mutant zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS) | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ... | Authors: | Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2017-04-28 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.319 Å) | Cite: | CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018
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5U7G
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![BU of 5u7g by Molmil](/molmil-images/mine/5u7g) | Crystal Structure of the Catalytic Core of CBP | Descriptor: | CREB-binding protein, ZINC ION | Authors: | Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E. | Deposit date: | 2016-12-12 | Release date: | 2017-06-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5VMV
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![BU of 5vmv by Molmil](/molmil-images/mine/5vmv) | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with its double CpG-methylated DNA consensus binding site | Descriptor: | CHLORIDE ION, DNA (5'-D(*TP*GP*CP*TP*TP*CP*TP*(5CM)P*GP*(5CM)P*GP*AP*GP*AP*AP*GP*CP*A)-3'), Transcriptional regulator Kaiso, ... | Authors: | Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2017-04-28 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.313 Å) | Cite: | CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018
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5VMX
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![BU of 5vmx by Molmil](/molmil-images/mine/5vmx) | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS) | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ... | Authors: | Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2017-04-28 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso. Biochemistry, 57, 2018
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4NCO
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![BU of 4nco by Molmil](/molmil-images/mine/4nco) | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP gp120, BG505 SOSIP gp41, ... | Authors: | Julien, J.-P, Stanfield, R.L, Lyumkis, D, Ward, A.B, Wilson, I.A. | Deposit date: | 2013-10-24 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (4.7 Å) | Cite: | Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science, 342, 2013
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4NWT
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![BU of 4nwt by Molmil](/molmil-images/mine/4nwt) | Crystal structure of the anti-human NGF Fab APE1531 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, APE1531 Ab Fab heavy chain, ... | Authors: | Verdino, P, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2013-12-06 | Release date: | 2014-10-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014
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4NWU
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![BU of 4nwu by Molmil](/molmil-images/mine/4nwu) | |