2R36
| Crystal structure of ni human ARG-insulin | Descriptor: | CHLORIDE ION, Insulin, NICKEL (II) ION, ... | Authors: | Sreekanth, R, Pattabhi, V, Rajan, S.S. | Deposit date: | 2007-08-29 | Release date: | 2008-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Metal induced structural changes observed in hexameric insulin Int.J.Biol.Macromol., 44, 2009
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2R35
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2QIU
| Structure of Human Arg-Insulin | Descriptor: | Insulin, ZINC ION | Authors: | Sreekanth, R, Pattabhi, V, Rajan, S.S. | Deposit date: | 2007-07-05 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural interpretation of reduced insulin activity as seen in the crystal structure of human Arg-insulin Biochimie, 90, 2008
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2R34
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4PPI
| Crystal structure of Bcl-xL hexamer | Descriptor: | Bcl-2-like protein 1, GLYCEROL | Authors: | Sreekanth, R, Yoon, H.S. | Deposit date: | 2014-02-27 | Release date: | 2015-03-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.851 Å) | Cite: | Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport Sci Rep, 5, 2015
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3UQI
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4QVF
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4QVE
| Crystal structure of Bcl-xL in complex with BID BH3 domain | Descriptor: | Bcl-2-like protein 1, IMIDAZOLE, Peptide from BH3-interacting domain death agonist | Authors: | Sreekanth, R, Yoon, H.S. | Deposit date: | 2014-07-14 | Release date: | 2015-06-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis. Proteins, 83, 2015
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5YD6
| Crystal structure of PG-bound Nurr1-LBD | Descriptor: | (~{Z})-7-[(1~{R},5~{S})-2-oxidanylidene-5-[(~{E},3~{S})-3-oxidanyloct-1-enyl]cyclopent-3-en-1-yl]hept-5-enoic acid, MAGNESIUM ION, Nuclear receptor subfamily 4 group A member 2 | Authors: | Sreekanth, R, Yoon, H.S. | Deposit date: | 2017-09-11 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structure of Nurr1 bound to cyclopentenone prostaglandin A2 and its mechanism of action in ameliorating dopaminergic neurodegeneration in Drosophila To Be Published
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5Y41
| Crystal Structure of LIGAND-BOUND NURR1-LBD | Descriptor: | (13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sreekanth, R, Lescar, J, Yoon, H.S. | Deposit date: | 2017-07-31 | Release date: | 2018-12-26 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function. Nat.Chem.Biol., 2020
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4J4O
| Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 in complex with D44 | Descriptor: | 70 kDa peptidylprolyl isomerase, putative, GLYCEROL, ... | Authors: | Sreekanth, R, Harikishore, A, Yoon, H.S. | Deposit date: | 2013-02-07 | Release date: | 2013-09-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent. Sci Rep, 3, 2013
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4J4N
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4JYS
| Crystal structure of FKBP25 from Plasmodium Vivax | Descriptor: | CHLORIDE ION, IMIDAZOLE, Peptidyl-prolyl cis-trans isomerase | Authors: | Sreekanth, R, Yoon, H.S. | Deposit date: | 2013-04-01 | Release date: | 2014-02-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity Proteins, 82, 2014
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4ITZ
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3M4Z
| Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site | Descriptor: | CHLORIDE ION, COBALT (II) ION, Ferrochelatase, ... | Authors: | Soderberg, C.A.G, Hansson, M.D, Sreekanth, R, Al-Karadaghi, S, Hansson, M. | Deposit date: | 2010-03-12 | Release date: | 2010-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase To be Published
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5XGB
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5XGE
| Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with cyclic di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein PA0861 | Authors: | Liu, C, Liew, C.W, Sreekanth, R, Lescar, J. | Deposit date: | 2017-04-13 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa. J. Bacteriol., 200, 2018
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6AC9
| Crystal structure of human Vaccinia-related kinase 1 (VRK1) in complex with AMP-PNP | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Ngow, Y.S, Sreekanth, R, Yoon, H.S. | Deposit date: | 2018-07-25 | Release date: | 2018-12-26 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of human vaccinia-related kinase 1 in complex with AMP-PNP, a non-hydrolyzable ATP analog. Protein Sci., 28, 2019
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5XGD
| Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Uncharacterized protein PA0861 | Authors: | Liu, C, Liew, C.W, Sreekanth, R, Lescar, J. | Deposit date: | 2017-04-13 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa. J. Bacteriol., 200, 2018
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