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PDB: 297 results

6BRR
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Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites
Descriptor: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
Authors:Zhang, Z.M, Song, J.
Deposit date:2017-11-30
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
6P4N
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Salmonella typhi PltB Homopentamer with Neu5Ac-alpha-2-6-Gal-beta-1-4-GlcNAc Glycans
Descriptor: N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Putative pertussis-like toxin subunit
Authors:Nguyen, T, Milano, S.K, Hillpot, E.C, Yang, Y.A, Song, J.
Deposit date:2019-05-28
Release date:2020-03-25
Last modified:2020-08-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence.
Cell Host Microbe, 27, 2020
6P4S
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Salmonella typhi PltB Homopentamer T65I Mutant
Descriptor: Putative pertussis-like toxin subunit
Authors:Nguyen, T, Milano, S.K, Hillpot, E.C, Yang, Y.A, Song, J.
Deposit date:2019-05-28
Release date:2020-03-25
Last modified:2020-08-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence.
Cell Host Microbe, 27, 2020
6P4P
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BU of 6p4p by Molmil
Salmonella typhi PltB Homopentamer N29K Mutant
Descriptor: Putative pertussis-like toxin subunit
Authors:Nguyen, T, Milano, S.K, Hillpot, E.C, Yang, Y.A, Song, J.
Deposit date:2019-05-28
Release date:2020-03-25
Last modified:2020-08-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Salmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence.
Cell Host Microbe, 27, 2020
6JPQ
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BU of 6jpq by Molmil
CryoEM structure of Abo1 hexamer - ADP complex
Descriptor: Uncharacterized AAA domain-containing protein C31G5.19
Authors:Cho, C, Jang, J, Song, J.J.
Deposit date:2019-03-27
Release date:2020-08-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.44 Å)
Cite:Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone.
Nat Commun, 10, 2019
8JBJ
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Crystal structure of anti-PVRIG Fab
Descriptor: antibody heavy chain, antibody light chain
Authors:Sun, J, Li, X.L, Song, J.
Deposit date:2023-05-09
Release date:2023-06-21
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity.
Mabs, 15, 2023
8JUW
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BU of 8juw by Molmil
Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
8JUZ
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Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state (Class III)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (4.29 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
8JUY
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Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state (Class II)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
4WXX
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BU of 4wxx by Molmil
The crystal structure of human DNMT1(351-1600)
Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Zhang, Z.M, Song, J.
Deposit date:2014-11-14
Release date:2015-07-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.622 Å)
Cite:Crystal Structure of Human DNA Methyltransferase 1.
J.Mol.Biol., 427, 2015
8JEL
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BU of 8jel by Molmil
Crystal structure of TIGIT in complexed with Ociperlimab, crystal form I
Descriptor: T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain
Authors:Sun, J, Zhang, X.X, Song, J.
Deposit date:2023-05-16
Release date:2024-02-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8JEN
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Crystal structure of TIGIT in complexed with Ociperlimab, crystal form II
Descriptor: T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain
Authors:Sun, J, Zhang, X.X, Song, J.
Deposit date:2023-05-16
Release date:2024-02-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8JEO
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Crystal structure of TIGIT in complexed with Tiragolumab
Descriptor: T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain
Authors:Sun, J, Zhang, X.X, Song, J.
Deposit date:2023-05-16
Release date:2024-02-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8JEP
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BU of 8jep by Molmil
Crystal structure of Ociperlimab
Descriptor: antibody heavy chain, antibody light chain
Authors:Sun, J, Zhang, X.X, Song, J.
Deposit date:2023-05-16
Release date:2024-02-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8JEQ
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BU of 8jeq by Molmil
Crystal structure of Tiragolumab
Descriptor: antibody heavy chain, antibody light chain
Authors:Sun, J, Zhang, X.X, Song, J.
Deposit date:2023-05-16
Release date:2024-02-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
6RMH
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BU of 6rmh by Molmil
The Rigid-body refined model of the normal Huntingtin.
Descriptor: Huntingtin
Authors:Jung, T, Tamo, G, Dal Perraro, M, Hebert, H, Song, J.
Deposit date:2019-05-06
Release date:2020-06-03
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain.
Structure, 28, 2020
6F57
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BU of 6f57 by Molmil
Crystal structure of DNMT3A-DNMT3L in complex with single CpG-containing DNA
Descriptor: DNA (5'-D(*AP*GP*AP*GP*CP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*ZP*GP*CP*TP*CP*T)-3'), DNA (cytosine-5)-methyltransferase 3-like, ...
Authors:Zhang, Z.M, Song, J.
Deposit date:2017-12-01
Release date:2018-01-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.098 Å)
Cite:Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
6PZV
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BU of 6pzv by Molmil
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
Descriptor: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ...
Authors:Ren, W, Song, J.
Deposit date:2019-08-01
Release date:2020-07-15
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
7LO8
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BU of 7lo8 by Molmil
NorA in complex with Fab36
Descriptor: Fab36 Heavy Chain, Fab36 Light Chain, Quinolone resistance protein NorA
Authors:Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N.
Deposit date:2021-02-09
Release date:2022-04-20
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
7LO7
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BU of 7lo7 by Molmil
NorA in complex with Fab25
Descriptor: Fab25 Heavy Chain, Fab25 Light Chain, Quinolone resistance protein NorA
Authors:Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N.
Deposit date:2021-02-09
Release date:2022-04-20
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
8EIH
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BU of 8eih by Molmil
Cryo-EM structure of human DNMT3B homo-tetramer (form I)
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Lu, J.W, Song, J.K.
Deposit date:2022-09-15
Release date:2023-09-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
8EII
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BU of 8eii by Molmil
Cryo-EM structure of human DNMT3B homo-tetramer (form II)
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Lu, J.W, Song, J.K.
Deposit date:2022-09-15
Release date:2023-09-20
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
8EIK
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BU of 8eik by Molmil
Cryo-EM structure of human DNMT3B homo-hexamer
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Lu, J.W, Song, J.K.
Deposit date:2022-09-15
Release date:2023-09-20
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
8EIJ
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BU of 8eij by Molmil
Cryo-EM structure of human DNMT3B homo-trimer
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Lu, J.W, Song, J.K.
Deposit date:2022-09-15
Release date:2023-09-20
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
6WU2
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BU of 6wu2 by Molmil
Structure of the LaINDY-malate complex
Descriptor: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
Authors:Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020

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數據於2024-06-26公開中

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