6W8D
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![BU of 6w8d by Molmil](/molmil-images/mine/6w8d) | Structure of DNMT3A (R882H) in complex with CGT DNA | Descriptor: | CGT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... | Authors: | Anteneh, H, Song, J. | Deposit date: | 2020-03-20 | Release date: | 2020-04-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.598 Å) | Cite: | Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Nat Commun, 11, 2020
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4RL5
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![BU of 4rl5 by Molmil](/molmil-images/mine/4rl5) | |
6W8J
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![BU of 6w8j by Molmil](/molmil-images/mine/6w8j) | Structure of DNMT3A (R882H) in complex with CAG DNA | Descriptor: | CAG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... | Authors: | Anteneh, H, Song, J. | Deposit date: | 2020-03-20 | Release date: | 2020-04-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.445 Å) | Cite: | Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Nat Commun, 11, 2020
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3FHQ
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![BU of 3fhq by Molmil](/molmil-images/mine/3fhq) | Structure of endo-beta-N-acetylglucosaminidase A | Descriptor: | 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, Endo-beta-N-acetylglucosaminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose | Authors: | Jie, Y, Li, L, Shaw, N, Li, Y, Song, J, Zhang, W, Xia, C, Zhang, R, Joachimiak, A, Zhang, H.-C, Wang, L.-X, Wang, P, Liu, Z.-J. | Deposit date: | 2008-12-10 | Release date: | 2009-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.452 Å) | Cite: | Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A Plos One, 4, 2009
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2QCY
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![BU of 2qcy by Molmil](/molmil-images/mine/2qcy) | |
6P3W
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![BU of 6p3w by Molmil](/molmil-images/mine/6p3w) | |
6W89
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![BU of 6w89 by Molmil](/molmil-images/mine/6w89) | Structure of DNMT3A (R882H) in complex with CGA DNA | Descriptor: | CGA DNA (25-MER), CITRIC ACID, DNA (cytosine-5)-methyltransferase 3-like, ... | Authors: | Anteneh, H, Song, J. | Deposit date: | 2020-03-20 | Release date: | 2020-04-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Nat Commun, 11, 2020
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7LMM
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![BU of 7lmm by Molmil](/molmil-images/mine/7lmm) | |
7LMK
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![BU of 7lmk by Molmil](/molmil-images/mine/7lmk) | |
7K7H
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![BU of 7k7h by Molmil](/molmil-images/mine/7k7h) | Density-fitted Model Structure of Antibody Variable Domains of TyTx1 in Complex with PltB pentamer of Typhoid Toxin | Descriptor: | Fab Heavy Chain Variable Domain, Fab Light Chain Variable Domain, Pertussis like toxin subunit B, ... | Authors: | Nguyen, T, Feathers, J.R, Fromme, J.C, Song, J. | Deposit date: | 2020-09-22 | Release date: | 2021-09-01 | Last modified: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Cell Rep, 36, 2021
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7K7I
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![BU of 7k7i by Molmil](/molmil-images/mine/7k7i) | Density-fitted Model Structure of Antibody Variable Domains of TyTx4 in Complex with PltB pentamer of Typhoid Toxin | Descriptor: | Fab Heavy Chain Variable Domain, Fab Light Chain Variable Domain, Putative pertussis-like toxin subunit | Authors: | Nguyen, T, Feathers, J.R, Fromme, J.C, Song, J. | Deposit date: | 2020-09-22 | Release date: | 2021-09-01 | Last modified: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Cell Rep, 36, 2021
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6UX2
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![BU of 6ux2 by Molmil](/molmil-images/mine/6ux2) | Crystal structure of ZIKV RdRp in complex with STAT2 | Descriptor: | Nonstructural Protein 5, SULFATE ION, Signal transducer and activator of transcription 2, ... | Authors: | Wang, B, Song, J. | Deposit date: | 2019-11-06 | Release date: | 2020-07-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural basis for STAT2 suppression by flavivirus NS5. Nat.Struct.Mol.Biol., 27, 2020
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7L4C
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![BU of 7l4c by Molmil](/molmil-images/mine/7l4c) | Crystal structure of the DRM2-CTT DNA complex | Descriptor: | DNA (5'-D(*AP*TP*TP*AP*TP*TP*AP*AP*TP*(C49)P*TP*TP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*AP*AP*GP*AP*TP*TP*AP*AP*TP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... | Authors: | Fang, J, Song, J. | Deposit date: | 2020-12-18 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
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7L4K
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![BU of 7l4k by Molmil](/molmil-images/mine/7l4k) | Crystal structure of the DRM2-CCG DNA complex | Descriptor: | DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*CP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*GP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... | Authors: | Fang, J, Song, J. | Deposit date: | 2020-12-19 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
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7L4H
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![BU of 7l4h by Molmil](/molmil-images/mine/7l4h) | Crystal structure of the DRM2-CTG DNA complex | Descriptor: | DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*TP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*AP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... | Authors: | Fang, J, Song, J. | Deposit date: | 2020-12-19 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
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7L4N
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![BU of 7l4n by Molmil](/molmil-images/mine/7l4n) | Crystal structure of the DRM2 (C397R)-CCG DNA complex | Descriptor: | DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*CP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*GP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... | Authors: | Fang, J, Song, J. | Deposit date: | 2020-12-19 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.247 Å) | Cite: | Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
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7L4M
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![BU of 7l4m by Molmil](/molmil-images/mine/7l4m) | Crystal structure of the DRM2-CCT DNA complex | Descriptor: | DNA (5'-D(*TP*AP*AP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*AP*T)-3'), DNA (5'-D(P*AP*TP*TP*CP*CP*TP*CP*CP*TP*(C49)P*CP*TP*CP*CP*TP*TP*TP*A)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... | Authors: | Fang, J, Song, J. | Deposit date: | 2020-12-19 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
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7L4F
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![BU of 7l4f by Molmil](/molmil-images/mine/7l4f) | Crystal structure of the DRM2-CAT DNA complex | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*AP*TP*TP*CP*CP*TP*CP*CP*TP*(C49)P*AP*TP*CP*CP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*GP*GP*AP*TP*GP*AP*GP*GP*AP*GP*GP*AP*AP*T)-3'), ... | Authors: | Fang, J, Song, J. | Deposit date: | 2020-12-19 | Release date: | 2021-08-04 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Substrate deformation regulates DRM2-mediated DNA methylation in plants. Sci Adv, 7, 2021
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6W8B
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![BU of 6w8b by Molmil](/molmil-images/mine/6w8b) | Structure of DNMT3A in complex with CGA DNA | Descriptor: | CGA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... | Authors: | Anteneh, H, Song, J. | Deposit date: | 2020-03-20 | Release date: | 2020-04-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Nat Commun, 11, 2020
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1BGK
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![BU of 1bgk by Molmil](/molmil-images/mine/1bgk) | SEA ANEMONE TOXIN (BGK) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL, NMR, 15 STRUCTURES | Descriptor: | BGK | Authors: | Dauplais, M, Lecoq, A, Song, J, Cotton, J, Jamin, N, Gilquin, B, Roumestand, C, Vita, C, Harvey, A, Menez, A. | Deposit date: | 1996-05-08 | Release date: | 1997-01-27 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures. J.Biol.Chem., 272, 1997
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5TMH
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![BU of 5tmh by Molmil](/molmil-images/mine/5tmh) | Structure of Zika virus NS5 | Descriptor: | GLYCEROL, Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Wang, B, Tan, X, Song, J. | Deposit date: | 2016-10-12 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.278 Å) | Cite: | The structure of Zika virus NS5 reveals a conserved domain conformation. Nat Commun, 8, 2017
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6U8X
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![BU of 6u8x by Molmil](/molmil-images/mine/6u8x) | Crystal structure of DNMT3B-DNMT3L in complex with CpApG DNA | Descriptor: | CpApG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Gao, L, Song, J. | Deposit date: | 2019-09-06 | Release date: | 2020-06-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.95063877 Å) | Cite: | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
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6UCA
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![BU of 6uca by Molmil](/molmil-images/mine/6uca) | Crystal structure of human ZCCHC4 in complex with SAH | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, rRNA N6-adenosine-methyltransferase ZCCHC4 | Authors: | Lu, J.W, Ren, W.D, Huang, M.J, Gao, L, Li, D.X, Wang, G.G, Song, J. | Deposit date: | 2019-09-15 | Release date: | 2019-10-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.103 Å) | Cite: | Structure and regulation of ZCCHC4 in m6A-methylation of 28S rRNA. Nat Commun, 10, 2019
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8T1U
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![BU of 8t1u by Molmil](/molmil-images/mine/8t1u) | Crystal structure of the DRM2-CTA DNA complex | Descriptor: | DNA (5'-D(P*AP*TP*TP*AP*TP*TP*AP*AP*TP*(C49)P*TP*AP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*TP*TP*TP*AP*GP*AP*TP*TP*AP*AP*TP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... | Authors: | Chen, J, Lu, J, Song, J. | Deposit date: | 2023-06-03 | Release date: | 2023-11-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | DNA conformational dynamics in the context-dependent non-CG CHH methylation by plant methyltransferase DRM2. J.Biol.Chem., 299, 2023
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6U8P
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![BU of 6u8p by Molmil](/molmil-images/mine/6u8p) | Crystal structure of DNMT3B-DNMT3L in complex with CpGpA DNA | Descriptor: | CpGpA DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Gao, L, Song, J. | Deposit date: | 2019-09-05 | Release date: | 2020-06-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
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