4KG8
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![BU of 4kg8 by Molmil](/molmil-images/mine/4kg8) | Crystal structure of light mutant | Descriptor: | Tumor necrosis factor ligand superfamily member 14 | Authors: | Liu, W, Zhan, C, Kumar, P.R, Bonanno, J.B, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2013-04-28 | Release date: | 2013-08-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly. Structure, 22, 2014
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3RNK
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![BU of 3rnk by Molmil](/molmil-images/mine/3rnk) | Crystal structure of the complex between mouse PD-1 mutant and PD-L2 IgV domain | Descriptor: | Programmed cell death 1 ligand 2, Programmed cell death protein 1 | Authors: | Lazar-Molnar, E, Ramagopal, U.A, Cao, E, Nathenson, S.G, Almo, S.C. | Deposit date: | 2011-04-22 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystal structure of the complex between mouse PD-1 mutant and PD-L2 IgV domain To be Published
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5TEU
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![BU of 5teu by Molmil](/molmil-images/mine/5teu) | Brucella periplasmic binding protein YehZ | Descriptor: | ACETATE ION, L(+)-TARTARIC ACID, SULFATE ION, ... | Authors: | Herrou, J, Crosson, S. | Deposit date: | 2016-09-22 | Release date: | 2017-01-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Conserved ABC Transport System Regulated by the General Stress Response Pathways of Alpha- and Gammaproteobacteria. J. Bacteriol., 199, 2017
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1BPE
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![BU of 1bpe by Molmil](/molmil-images/mine/1bpe) | CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA; EVIDENCE FOR A COMMON POLYMERASE MECHANISM | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA POLYMERASE BETA | Authors: | Sawaya, M.R, Pelletier, H, Kumar, A, Wilson, S.H, Kraut, J. | Deposit date: | 1994-04-12 | Release date: | 1994-07-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. Science, 264, 1994
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4NEV
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![BU of 4nev by Molmil](/molmil-images/mine/4nev) | Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor EP127 (5-{5-[1-(PYRROLIDIN-1-YL)CYCLOHEXYL]-1,3-THIAZOL-2-YL}-1H-INDOLE) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1H-indole, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Persch, E, Bryson, S, Pai, E.F, Krauth-Siegel, R.L, Diederich, F. | Deposit date: | 2013-10-30 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductase. Chemmedchem, 9, 2014
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3EGS
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![BU of 3egs by Molmil](/molmil-images/mine/3egs) | Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 scrambledFP-MPER scrHyb3K construct GIGAFGLLGFLAAGSKK-Ahx-K656NEQELLELDKWASLWN671 soaked in ammonium sulfate | Descriptor: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, gp41 scrFP-MPER construct | Authors: | Julien, J.-P, Bryson, S, de la Torre, B.G, Andreu, D, Nieva, J.L, Pai, E.F. | Deposit date: | 2008-09-11 | Release date: | 2009-08-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5. J.Phys.Chem.B, 113, 2009
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1BNO
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![BU of 1bno by Molmil](/molmil-images/mine/1bno) | NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA, MINIMIZED AVERAGE STRUCTURE | Descriptor: | DNA POLYMERASE BETA | Authors: | Liu, D.-J, Prasad, R, Wilson, S.H, Derose, E.F, Mullen, G.P. | Deposit date: | 1996-04-25 | Release date: | 1996-12-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface. Biochemistry, 35, 1996
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4KGG
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![BU of 4kgg by Molmil](/molmil-images/mine/4kgg) | Crystal structure of light mutant2 and dcr3 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 14, ... | Authors: | Liu, W, Bonanno, J.B, Zhan, C, Kumar, P.R, Toro, R, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-04-29 | Release date: | 2013-08-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly. Structure, 22, 2014
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1BNP
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![BU of 1bnp by Molmil](/molmil-images/mine/1bnp) | NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA, 55 STRUCTURES | Descriptor: | DNA POLYMERASE BETA | Authors: | Liu, D.-J, Prasad, R, Wilson, S.H, Derose, E.F, Mullen, G.P. | Deposit date: | 1996-04-25 | Release date: | 1996-12-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface. Biochemistry, 35, 1996
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1YHV
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![BU of 1yhv by Molmil](/molmil-images/mine/1yhv) | |
3RQ3
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![BU of 3rq3 by Molmil](/molmil-images/mine/3rq3) | Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT) in hexagonal crystal form | Descriptor: | CHLORIDE ION, T cell immunoreceptor with Ig and ITIM domains | Authors: | Ramagopal, U.A, Rubinstein, R, Guo, H, Samanta, D, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | Deposit date: | 2011-04-27 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT) in hexagonal crystal form To be published
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3RRQ
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![BU of 3rrq by Molmil](/molmil-images/mine/3rrq) | |
3QKQ
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![BU of 3qkq by Molmil](/molmil-images/mine/3qkq) | Protein Tyrosine Phosphatase 1B - W179F mutant bound with vanadate | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1, ... | Authors: | Brandao, T.A.S, Johnson, S.J, Hengge, A.C. | Deposit date: | 2011-02-01 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B. Arch.Biochem.Biophys., 525, 2012
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2IUH
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![BU of 2iuh by Molmil](/molmil-images/mine/2iuh) | Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with c-Kit phosphotyrosyl peptide | Descriptor: | C-KIT PHOSPHOTYROSYL PEPTIDE, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT | Authors: | Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. | Deposit date: | 2006-06-03 | Release date: | 2006-06-06 | Last modified: | 2021-04-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
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1EMT
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![BU of 1emt by Molmil](/molmil-images/mine/1emt) | FAB ANTIBODY FRAGMENT OF AN C60 ANTIFULLERENE ANTIBODY | Descriptor: | IGG ANTIBODY (HEAVY CHAIN), IGG ANTIBODY (LIGHT CHAIN) | Authors: | Braden, B.C, Goldbaum, F.A, Chen, B.-X, Erlanger, B.F, Kirschner, A.N, Wilson, S.R. | Deposit date: | 2000-03-17 | Release date: | 2000-11-01 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | X-ray crystal structure of an anti-Buckminsterfullerene antibody fab fragment: biomolecular recognition of C(60). Proc.Natl.Acad.Sci.USA, 97, 2000
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4QPJ
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![BU of 4qpj by Molmil](/molmil-images/mine/4qpj) | 2.7 Angstrom Structure of a Phosphotransferase in Complex with a Receiver Domain | Descriptor: | CALCIUM ION, CHLORIDE ION, Cell cycle response regulator CtrA, ... | Authors: | Willett, J.W, Herrou, J, Crosson, S. | Deposit date: | 2014-06-23 | Release date: | 2015-07-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.742 Å) | Cite: | Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen. Proc.Natl.Acad.Sci.USA, 112, 2015
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1YHW
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![BU of 1yhw by Molmil](/molmil-images/mine/1yhw) | |
2IUG
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![BU of 2iug by Molmil](/molmil-images/mine/2iug) | Crystal structure of the PI3-kinase p85 N-terminal SH2 domain | Descriptor: | PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT | Authors: | Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. | Deposit date: | 2006-06-03 | Release date: | 2006-06-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
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2IUI
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![BU of 2iui by Molmil](/molmil-images/mine/2iui) | Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with PDGFR phosphotyrosyl peptide | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Platelet-derived growth factor receptor beta | Authors: | Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. | Deposit date: | 2006-06-03 | Release date: | 2006-06-06 | Last modified: | 2021-04-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Pi 3-Kinase P85 Amino- Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
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3F5K
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![BU of 3f5k by Molmil](/molmil-images/mine/3f5k) | Semi-active E176Q mutant of rice BGlu1, a plant exoglucanase/beta-glucosidase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase, GLYCEROL, ... | Authors: | Chuenchor, W, Ketudat Cairns, J.R, Pengthaisong, S, Robinson, R.C, Yuvaniyama, J, Chen, C.-J. | Deposit date: | 2008-11-03 | Release date: | 2009-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase J.Struct.Biol., 173, 2011
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3QKP
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![BU of 3qkp by Molmil](/molmil-images/mine/3qkp) | Protein Tyrosine Phosphatase 1B - Apo W179F mutant with open WPD-loop | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Brandao, T.A.S, Johnson, S.J, Hengge, A.C. | Deposit date: | 2011-02-01 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B. Arch.Biochem.Biophys., 525, 2012
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3EYQ
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![BU of 3eyq by Molmil](/molmil-images/mine/3eyq) | Crystal structure of MJ5 Fab, a germline antibody variant of anti-human cytomegalovirus antibody 8f9 | Descriptor: | 8f9 Fab, M2J5 Fab | Authors: | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | Deposit date: | 2008-10-21 | Release date: | 2008-12-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
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3EYF
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![BU of 3eyf by Molmil](/molmil-images/mine/3eyf) | Crystal structure of anti-human cytomegalovirus antibody 8f9 plus gB peptide | Descriptor: | 8f9 Fab, AD-2, GLYCEROL, ... | Authors: | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | Deposit date: | 2008-10-20 | Release date: | 2008-12-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
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3NO9
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![BU of 3no9 by Molmil](/molmil-images/mine/3no9) | Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis | Descriptor: | Fumarate hydratase class II | Authors: | Li, H, Swanson, S, Yu, M, Hung, L.-W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-06-25 | Release date: | 2010-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis To be Published
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1FVT
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![BU of 1fvt by Molmil](/molmil-images/mine/1fvt) | THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH AN OXINDOLE INHIBITOR | Descriptor: | 4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzene-1-sulfonamide, CELL DIVISION PROTEIN KINASE 2 | Authors: | Davis, S.T, Benson, B.G, Bramson, H.N, Chapman, D.E, Dickerson, S.H, Dold, K.M, Eberwein, D.J, Edelstein, M, Frye, S.V, Gampe Jr, R.T, Griffin, R.J, Harris, P.A, Hassell, A.M, Holmes, W.D, Hunter, R.N, Knick, V.B, Lackey, K, Lovejoy, B, Luzzio, M.J, Murray, D, Parker, P, Rocque, W.J, Shewchuk, L, Veal, J.M, Walker, D.H, Kuyper, L.K. | Deposit date: | 2000-09-20 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science, 291, 2001
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