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PDB: 1980 件

7L7Q
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Ctf3c with Ulp2-KIM
分子名称: Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, Inner kinetochore subunit MCM22
著者Hinshaw, S.M, Harrison, S.C.
登録日2020-12-30
公開日2021-02-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ctf3/CENP-I provides a docking site for the desumoylase Ulp2 at the kinetochore.
J.Cell Biol., 220, 2021
3SQI
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DNA binding domain of Ndc10
分子名称: DNA (5'-D(P*AP*AP*AP*TP*TP*TP*TP*AP*TP*AP*AP*AP*TP*TP*A)-3'), DNA (5'-D(P*TP*TP*AP*AP*TP*TP*TP*AP*TP*AP*AP*AP*AP*TP*T)-3'), KLLA0E03807p
著者Cho, U.S, Harrison, S.C.
登録日2011-07-05
公開日2011-12-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8245 Å)
主引用文献Ndc10 is a platform for inner kinetochore assembly in budding yeast.
Nat.Struct.Mol.Biol., 19, 2011
5UNH
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Synchrotron structure of human angiotensin II type 2 receptor in complex with compound 2 (N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'- biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide)
分子名称: N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide, Soluble cytochrome b562,Type-2 angiotensin II receptor
著者Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V.
登録日2017-01-30
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
5TPP
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Crystal Structure of DH270.5 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
分子名称: CITRIC ACID, DH270.5 Fab heavy chain, DH270.5 Fab light chain, ...
著者Fera, D, Harrison, S.C.
登録日2016-10-20
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5UIX
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BU of 5uix by Molmil
Crystal Structure of the DH576 CD4bs Fab (unliganded) from the RV305 HIV Vaccine Trial
分子名称: DH576 Fab heavy chain, DH576 Fab light chain
著者Fera, D, Harrison, S.C.
登録日2017-01-15
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.
PLoS Pathog., 13, 2017
2SGF
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BU of 2sgf by Molmil
PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
To be Published
1XDV
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Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
分子名称: Son of sevenless protein homolog 1
著者Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
登録日2004-09-08
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
2SGD
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ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ...
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
To be Published
5UNG
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BU of 5ung by Molmil
XFEL structure of human angiotensin II type 2 receptor (Orthorhombic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl] methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide)
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562, N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide, ...
著者Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V.
登録日2017-01-30
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
5F6I
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Crystal Structure of Tier 2 Neutralizing Antibody DH428 from a Rhesus Macaque
分子名称: DH428 Antibody Heavy Chain, DH428 Antibody Light Chain
著者Fera, D, Harrison, S.C.
登録日2015-12-06
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site.
Cell Rep, 14, 2016
3T79
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BU of 3t79 by Molmil
Ndc10: a platform for inner kinetochore assembly in budding yeast
分子名称: DNA (5'-D(P*AP*AP*AP*AP*AP*TP*TP*TP*TP*AP*TP*AP*AP*AP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*TP*TP*TP*AP*TP*AP*AP*AP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*TP*TP*TP*AP*TP*AP*AP*AP*AP*TP*T)-3'), ...
著者Cho, U.S, Harrison, S.C.
登録日2011-07-29
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.6113 Å)
主引用文献Ndc10 is a platform for inner kinetochore assembly in budding yeast.
Nat.Struct.Mol.Biol., 19, 2011
3BP6
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BU of 3bp6 by Molmil
Crystal structure of the mouse PD-1 Mutant and PD-L2 complex
分子名称: GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1
著者Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C.
登録日2007-12-18
公開日2009-02-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the mouse PD-1 A99L and PD-L2 complex
To be published
3JZZ
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BU of 3jzz by Molmil
Crystal structure of Pseudomonas aeruginosa (strain: Pa110594) typeIV pilin in space group P212121
分子名称: Type IV pilin structural subunit
著者Nguyen, Y, Jackson, S.G, Aidoo, F, Junop, M.S, Burrows, L.L.
登録日2009-09-24
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.597 Å)
主引用文献Structural characterization of Novel Pseudomonas aeruginosa type IV pilins.
J.Mol.Biol., 395, 2010
3BP5
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Crystal structure of the mouse PD-1 and PD-L2 complex
分子名称: GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1
著者Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C.
登録日2007-12-18
公開日2008-07-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BOV
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BU of 3bov by Molmil
Crystal structure of the receptor binding domain of mouse PD-L2
分子名称: FORMIC ACID, Programmed cell death 1 ligand 2, SODIUM ION
著者Lazar-Molnar, E, Ramagopal, U, Cao, E, Toro, R, Nathenson, S.G, Almo, S.C.
登録日2007-12-17
公開日2008-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.USA, 105, 2008
3SBW
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BU of 3sbw by Molmil
Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1
分子名称: Programmed cell death 1 ligand 1, Programmed cell death protein 1
著者Lazar-Molnar, E, Ramagopal, U.A, Cao, E, Nathenson, S.G, Almo, S.C.
登録日2011-06-06
公開日2011-07-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1
To be published
5UNF
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BU of 5unf by Molmil
XFEL structure of human angiotensin II type 2 receptor (Monoclinic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl])
分子名称: Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562, N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide
著者Zhang, H, Han, G.W, Batyuk, A, Ishchenko, A, White, K.L, Patel, N, Sadybekov, A, Zamlynny, B, Rudd, M.T, Hollenstein, K, Tolstikova, A, White, T.A, Hunter, M.S, Weierstall, U, Liu, W, Babaoglu, K, Moore, E.L, Katz, R.D, Shipman, J.M, Garcia-Calvo, M, Sharma, S, Sheth, P, Soisson, S.M, Stevens, R.C, Katritch, V, Cherezov, V.
登録日2017-01-30
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
1VZV
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BU of 1vzv by Molmil
STRUCTURE OF VARICELLA-ZOSTER VIRUS PROTEASE
分子名称: VARICELLA-ZOSTER VIRUS PROTEASE
著者Qiu, X, Jason, C.A, Culp, J.S, Richardson, S.B, Debouck, C, Smith, W.W, Abdel-Meguid, S.S.
登録日1997-02-10
公開日1998-09-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of varicella-zoster virus protease.
Proc.Natl.Acad.Sci.USA, 94, 1997
3B8F
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Crystal structure of the cytidine deaminase from Bacillus anthracis
分子名称: Putative Blasticidin S deaminase
著者Zhang, R, Joachimiak, G, Wu, R, Patterson, S, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-11-01
公開日2007-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of the cytidine deaminase from Bacillus anthracis.
To be Published
5TQA
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BU of 5tqa by Molmil
Crystal Structure of DH270.6 (unliganded) from the DH270 Broadly Neutralizing N332-Glycan Dependent Lineage
分子名称: DH270.6 Fab heavy chain, DH270.6 Fab light chain
著者Fera, D, Harrison, S.C.
登録日2016-10-23
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.723 Å)
主引用文献Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5TRP
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BU of 5trp by Molmil
Crystal Structure of the Unliganded DH270 Cooperating Lineage Member DH272
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH272 Fab heavy chain, DH272 Fab light chain, ...
著者Fera, D, Harrison, S.C.
登録日2016-10-27
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.692 Å)
主引用文献Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
2VML
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BU of 2vml by Molmil
The monoclinic structure of phycocyanin from Gloeobacter violaceus
分子名称: PHYCOCYANIN ALPHA CHAIN, PHYCOCYANIN BETA CHAIN, PHYCOCYANOBILIN
著者Murray, J.W, Benson, S, Barber, J.
登録日2008-01-28
公開日2008-03-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structures of the Phycobiliproteins of Gloeobacter Violaceus
To be Published
2YFW
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Heterotetramer structure of Kluyveromyces lactis Cse4,H4
分子名称: HISTONE H3-LIKE CENTROMERIC PROTEIN CSE4, HISTONE H4
著者Cho, U.S, Harrison, S.C.
登録日2011-04-08
公開日2011-05-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Recognition of the Centromere-Specific Histone Cse4 by the Chaperone Scm3.
Proc.Natl.Acad.Sci.USA, 108, 2011
4QF1
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BU of 4qf1 by Molmil
Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
著者Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2014-05-19
公開日2015-02-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
5WAL
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BU of 5wal by Molmil
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
分子名称: N-[2-(2,6-dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamide, Non-receptor tyrosine-protein kinase TYK2
著者Ultsch, M.H, Magnuson, S.
登録日2017-06-26
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.
Bioorg. Med. Chem. Lett., 27, 2017

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