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1YSA
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THE GCN4 BASIC REGION LEUCINE ZIPPER BINDS DNA AS A DIMER OF UNINTERRUPTED ALPHA HELICES: CRYSTAL STRUCTURE OF THE PROTEIN-DNA COMPLEX
Descriptor: DNA (5'-D(*AP*AP*AP*CP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*A P*GP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*A P*GP*TP*T)-3'), PROTEIN (GCN4)
Authors:Ellenberger, T.E, Brandl, C.J, Struhl, K, Harrison, S.C.
Deposit date:1993-08-09
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex.
Cell(Cambridge,Mass.), 71, 1992
2D03
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Crystal structure of the G91S mutant of the NNA7 Fab
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Xie, K, Song, S.C, Spitalnik, S.L, Wedekind, J.E.
Deposit date:2005-07-23
Release date:2006-01-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystallographic analysis of the NNA7 Fab and proposal for the mode of human blood-group recognition.
Acta Crystallogr.,Sect.D, 61, 2005
2D1F
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Structure of Mycobacterium tuberculosis threonine synthase
Descriptor: PYRIDOXAL-5'-PHOSPHATE, Threonine synthase
Authors:Covarrubias, A.S, Bergfors, T, Mannerstedt, K, Oscarson, S, Jones, T.A, Mowbray, S.L, Hogbom, M.
Deposit date:2005-08-20
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural, biochemical, and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis.
J.Mol.Biol., 381, 2008
4G4F
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Crystal structure of GITRL from Bushbaby
Descriptor: Tumor necrosis factor ligand superfamily member 18
Authors:Kumar, P.R, Bhosle, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-07-16
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Crystal structure of GITRL from Otolemur garnettii
to be published
2QE3
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Crystal structure of human tl1a extracellular domain
Descriptor: CHLORIDE ION, TNF superfamily ligand TL1A
Authors:Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C.
Deposit date:2007-06-22
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
2QDN
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Crystal Structure of mouse GITRL
Descriptor: GITR ligand
Authors:Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2007-06-21
Release date:2008-01-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2QDF
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Structure of N-terminal domain of E. Coli YaeT
Descriptor: MAGNESIUM ION, Outer membrane protein assembly factor yaeT
Authors:Kim, S, Malinverni, J.C, Sliz, P, Silhavy, T.J, Harrison, S.C, Kahne, D.
Deposit date:2007-06-20
Release date:2007-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and function of an essential component of the outer membrane protein assembly machine.
Science, 317, 2007
2QCZ
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Structure of N-terminal domain of E. Coli YaeT
Descriptor: Outer membrane protein assembly factor yaeT
Authors:Kim, S, Malinverni, J.C, Sliz, P, Silhavy, T.J, Harrison, S.C, Kahne, D.
Deposit date:2007-06-20
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and function of an essential component of the outer membrane protein assembly machine.
Science, 317, 2007
2R30
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Crystal Structure of human GITRL mutant
Descriptor: Tumor necrosis factor ligand superfamily member 18
Authors:Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2007-08-28
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.
Proc.Natl.Acad.Sci.USA, 104, 2007
2R7Q
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Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (C-terminal hexahistidine-tagged)
Descriptor: RNA-dependent RNA polymerase
Authors:Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
Deposit date:2007-09-09
Release date:2008-07-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2QUQ
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Crystal Structure of the Essential Inner Kinetochore Protein Cep3p
Descriptor: Centromere DNA-binding protein complex CBF3 subunit B
Authors:Bellizzi III, J.J, Harrison, S.C.
Deposit date:2007-08-06
Release date:2007-11-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the yeast inner kinetochore subunit Cep3p.
Structure, 15, 2007
2R2A
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Crystal structure of N-terminal domain of zonular occludens toxin from Neisseria meningitidis
Descriptor: SULFATE ION, Uncharacterized protein
Authors:Osipiuk, J, Patterson, S, Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-08-24
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of N-terminal domain of zonular occludens toxin from Neisseria meningitidis.
To be Published
2CSE
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BU of 2cse by Molmil
Features of Reovirus Outer-Capsid Protein mu1 Revealed by Electron and Image Reconstruction of the virion at 7.0-A Resolution
Descriptor: Minor core protein lambda 3, Sigma 2 protein, guanylyltransferase, ...
Authors:Zhang, X, Ji, Y, Zhang, L, Harrison, S.C, Marinescu, D.C, Nibert, M.L, Baker, T.S.
Deposit date:2005-05-21
Release date:2005-10-18
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolution.
Structure, 13, 2005
2P6B
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BU of 2p6b by Molmil
Crystal Structure of Human Calcineurin in Complex with PVIVIT Peptide
Descriptor: CALCIUM ION, Calcineurin subunit B isoform 1, Calmodulin-dependent calcineurin A subunit alpha isoform, ...
Authors:Li, H, Zhang, L, Rao, A, Harrison, S.C, Hogan, P.G.
Deposit date:2007-03-16
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of calcineurin in complex with PVIVIT peptide: Portrait of a low-affinity signalling interaction
J.Mol.Biol., 369, 2007
4F5X
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Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles
Descriptor: Intermediate capsid protein VP6, RNA-directed RNA polymerase, VP2 protein, ...
Authors:Estrozi, L.F, Settembre, E.C, Goret, G, McClain, B, Zhang, X, Chen, J.Z, Grigorieff, N, Harrison, S.C.
Deposit date:2012-05-13
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:Location of the dsRNA-Dependent Polymerase, VP1, in Rotavirus Particles.
J.Mol.Biol., 425, 2013
4FHQ
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Crystal Structure of HVEM
Descriptor: Tumor necrosis factor receptor superfamily member 14
Authors:Liu, W, Zhan, C, Patskovsky, Y, Bhosle, R.C, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-06-06
Release date:2012-07-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
Mol Biotechnol, 57, 2015
2R7U
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Crystal Structure of Rotavirus SA11 VP1/RNA (AAAAGCC) Complex
Descriptor: RNA (5'-R(*AP*A*AP*AP*GP*CP*C)-3'), RNA-dependent RNA polymerase
Authors:Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
Deposit date:2007-09-10
Release date:2008-07-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2RJK
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Crystal Structure of Human TL1A Extracellular Domain C95S Mutant
Descriptor: TNF superfamily ligand TL1A
Authors:Zhan, C, Yan, Q, Patskovsky, Y, Shi, W, Ramagopal, U.A, Toro, R, Bonanno, J, Nathenson, S.G, Almo, S.C.
Deposit date:2007-10-15
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
2R7X
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Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/GTP complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase
Authors:Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
Deposit date:2007-09-10
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2SGP
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PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
Descriptor: OVOMUCOID INHIBITOR, PHOSPHATE ION, PROTEINASE B
Authors:Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
Deposit date:1999-03-25
Release date:2001-01-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
2NU3
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Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
Descriptor: Ovomucoid, Streptogrisin B, Proteinase B
Authors:Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-11-08
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
7JIC
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BU of 7jic by Molmil
Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment
Descriptor: B-lymphocyte antigen CD19, CD81 antigen, Coltuximab Heavy Chain, ...
Authors:Susa, K.J, Rawson, S, Kruse, A.C, Blacklow, S.C.
Deposit date:2020-07-23
Release date:2021-01-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81
Science, 371, 2021
2R7W
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Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/mRNA 5'-CAP (m7GpppG) complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase
Authors:Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
Deposit date:2007-09-10
Release date:2008-07-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2SGQ
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GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
Descriptor: Ovomucoid, PHOSPHATE ION, Streptogrisin B
Authors:Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
Deposit date:1999-03-25
Release date:2003-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
2Q1M
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Crystal Structure of human GITRL
Descriptor: Tumor necrosis factor ligand superfamily member 18
Authors:Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2007-05-24
Release date:2007-11-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.
Proc.Natl.Acad.Sci.USA, 104, 2007

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