8STN
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![BU of 8stn by Molmil](/molmil-images/mine/8stn) | Crystal structure of KRAS-G12D/G75A mutant, GDP-bound | Descriptor: | CHLORIDE ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Tran, T.H, Dharmaiah, S, Simanshu, D.K. | Deposit date: | 2023-05-10 | Release date: | 2023-08-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity. Cancer Res., 83, 2023
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3Q0C
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![BU of 3q0c by Molmil](/molmil-images/mine/3q0c) | Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122 | Descriptor: | DNA (5'-D(*AP*CP*TP*AP*(5CM)P*GP*TP*AP*GP*TP*T)-3'), Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, ... | Authors: | Eerappa, R, Simanshu, D.K, Patel, D.J. | Deposit date: | 2010-12-15 | Release date: | 2011-02-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6567 Å) | Cite: | A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes Dev., 25, 2011
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3RIU
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![BU of 3riu by Molmil](/molmil-images/mine/3riu) | |
3Q0D
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![BU of 3q0d by Molmil](/molmil-images/mine/3q0d) | Crystal structure of SUVH5 SRA- hemi methylated CG DNA complex | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*TP*GP*AP*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*AP*(5CM)P*GP*TP*CP*AP*G)-3'), ... | Authors: | Eerappa, R, Simanshu, D.K, Patel, D.J. | Deposit date: | 2010-12-15 | Release date: | 2011-02-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3704 Å) | Cite: | A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes Dev., 25, 2011
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3O7X
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![BU of 3o7x by Molmil](/molmil-images/mine/3o7x) | |
3O3I
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![BU of 3o3i by Molmil](/molmil-images/mine/3o3i) | Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OH at its 3'-end | Descriptor: | Piwi-like protein 1, RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*U)-3') | Authors: | Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J. | Deposit date: | 2010-07-24 | Release date: | 2011-01-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proc.Natl.Acad.Sci.USA, 108, 2011
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3O7V
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![BU of 3o7v by Molmil](/molmil-images/mine/3o7v) | Crystal Structure of human Hiwi1 (V361M) PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OCH3 at its 3'-end | Descriptor: | Piwi-like protein 1, RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*(OMU))-3') | Authors: | Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J. | Deposit date: | 2010-08-01 | Release date: | 2011-01-12 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proc.Natl.Acad.Sci.USA, 108, 2011
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3O6E
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![BU of 3o6e by Molmil](/molmil-images/mine/3o6e) | Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OCH3 at its 3'-end | Descriptor: | Piwi-like protein 1, RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*(OMU))-3') | Authors: | Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J. | Deposit date: | 2010-07-28 | Release date: | 2011-01-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.904 Å) | Cite: | Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proc.Natl.Acad.Sci.USA, 108, 2011
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2HTA
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![BU of 2hta by Molmil](/molmil-images/mine/2hta) | Crystal Structure of a putative mutarotase (YeaD) from Salmonella typhimurium in orthorhombic form | Descriptor: | GLYCEROL, Putative enzyme related to aldose 1-epimerase, SULFATE ION | Authors: | Chittori, S, Simanshu, D.K, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2006-07-25 | Release date: | 2007-01-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the putative mutarotase YeaD from Salmonella typhimurium: structural comparison with galactose mutarotases. Acta Crystallogr.,Sect.D, 63, 2007
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2HTB
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![BU of 2htb by Molmil](/molmil-images/mine/2htb) | Crystal Structure of a putative mutarotase (YeaD) from Salmonella typhimurium in monoclinic form | Descriptor: | Putative enzyme related to aldose 1-epimerase | Authors: | Chittori, S, Simanshu, D.K, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2006-07-25 | Release date: | 2007-01-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the putative mutarotase YeaD from Salmonella typhimurium: structural comparison with galactose mutarotases. Acta Crystallogr.,Sect.D, 63, 2007
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2E7R
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![BU of 2e7r by Molmil](/molmil-images/mine/2e7r) | Crystal structure of Glu54 to Arg mutant of Diphthine synthase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Mizutani, H, Matsuura, Y, Krishna Swamy, B.S, Simanshu, D.K, Murthy, M.R.N, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-12 | Release date: | 2007-07-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3 To be Published
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2EGB
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![BU of 2egb by Molmil](/molmil-images/mine/2egb) | Crystal structure of Glu140 to Asn mutant of Diphthine synthase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Mizutani, H, Matsuura, Y, Krishna Swamy, B.S, Simanshu, D.K, Murthy, M.R.N, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-28 | Release date: | 2007-08-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3 To be Published
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2EGL
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![BU of 2egl by Molmil](/molmil-images/mine/2egl) | Crystal structure of Glu171 to Lys mutant of Diphthine synthase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Mizutani, H, Matsuura, Y, Krishna Swamy, B.S, Simanshu, D.K, Murthy, M.R.N, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-01 | Release date: | 2007-09-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3 To be Published
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2EGS
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![BU of 2egs by Molmil](/molmil-images/mine/2egs) | Crystal structure of Leu261 to Met mutant of Diphthine synthase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Mizutani, H, Matsuura, Y, Krishna Swamy, B.S, Simanshu, D.K, Murthy, M.R.N, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-02 | Release date: | 2007-09-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of diphthine synthase from Pyrococcus horikoshii OT3 To be Published
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4RGF
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![BU of 4rgf by Molmil](/molmil-images/mine/4rgf) | Crystal structure of the in-line aligned env22 twister ribozyme soaked with Mn2+ | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | Authors: | Ren, A, Rajashankar, K.R, Simanshu, D, Patel, D. | Deposit date: | 2014-09-30 | Release date: | 2014-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2008 Å) | Cite: | In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme. Nat Commun, 5, 2014
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4RGE
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![BU of 4rge by Molmil](/molmil-images/mine/4rge) | Crystal structure of the in-line aligned env22 twister ribozyme | Descriptor: | MAGNESIUM ION, env22 twister ribozyme | Authors: | Ren, A, Rajashankar, K.R, Simanshu, D, Patel, D. | Deposit date: | 2014-09-30 | Release date: | 2014-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme. Nat Commun, 5, 2014
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4NGD
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![BU of 4ngd by Molmil](/molmil-images/mine/4ngd) | Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having 5'-p and UU-3' ends (1.95 Angstrom resolution) | Descriptor: | 5'-R(P*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', DI(HYDROXYETHYL)ETHER, Endoribonuclease Dicer, ... | Authors: | Tian, Y, Simanshu, D.K, Patel, D.J. | Deposit date: | 2013-11-01 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.958 Å) | Cite: | A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer. Mol.Cell, 53, 2014
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4NH5
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![BU of 4nh5 by Molmil](/molmil-images/mine/4nh5) | |