4L79
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![BU of 4l79 by Molmil](/molmil-images/mine/4l79) | Crystal Structure of nucleotide-free Myosin 1b residues 1-728 with bound Calmodulin | Descriptor: | Calmodulin, MAGNESIUM ION, Unconventional myosin-Ib | Authors: | Shuman, H, Zwolak, A, Dominguez, R, Ostap, E.M. | Deposit date: | 2013-06-13 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning. Proc.Natl.Acad.Sci.USA, 111, 2014
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1JH5
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![BU of 1jh5 by Molmil](/molmil-images/mine/1jh5) | Crystal Structure of sTALL-1 of TNF family ligand | Descriptor: | TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B | Authors: | Liu, Y, Xu, L, Opalka, N, Shu, H.-B, Zhang, G. | Deposit date: | 2001-06-27 | Release date: | 2002-02-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. Cell(Cambridge,Mass.), 108, 2002
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4G1T
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![BU of 4g1t by Molmil](/molmil-images/mine/4g1t) | Crystal structure of interferon-stimulated gene 54 | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 2 | Authors: | Yang, Z, Liang, H, Zhou, Q, Li, Y, Chen, H, Ye, W, Chen, D, Fleming, J, Shu, H, Liu, Y. | Deposit date: | 2012-07-11 | Release date: | 2012-08-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms. Cell Res., 22, 2012
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6U2O
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![BU of 6u2o by Molmil](/molmil-images/mine/6u2o) | |
6U6B
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![BU of 6u6b by Molmil](/molmil-images/mine/6u6b) | Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ... | Authors: | Ouzon-Shubeita, H, Vilas, C.K, Lee, S. | Deposit date: | 2019-08-29 | Release date: | 2020-09-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.108 Å) | Cite: | Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion. Biochem.J., 477, 2020
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8R3T
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![BU of 8r3t by Molmil](/molmil-images/mine/8r3t) | Cofactor-free Tau 4R2N isoform | Descriptor: | Microtubule-associated protein tau | Authors: | Limorenko, G, Tatli, M, Kolla, R, Nazarov, S, Weil, M.T, Schondorf, D.C, Geist, D, Reinhardt, P, Ehrnhoefer, D.E, Stahlberg, H, Gasparini, L, Lashuel, H.A. | Deposit date: | 2023-11-10 | Release date: | 2023-12-06 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates. Nat Commun, 14, 2023
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5CHZ
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![BU of 5chz by Molmil](/molmil-images/mine/5chz) | |
6MXO
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![BU of 6mxo by Molmil](/molmil-images/mine/6mxo) | Structure of HPoleta incorporating dCTP opposite the 3-prime Pt(DACH)-GG | Descriptor: | (cyclohex-1-ene-1,2-diamine)platinum(2+), 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*CP*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... | Authors: | Ouzon-Shubeita, H, Lee, S. | Deposit date: | 2018-10-31 | Release date: | 2019-02-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase eta. Biochem. J., 476, 2019
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6C1G
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![BU of 6c1g by Molmil](/molmil-images/mine/6c1g) | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6C1H
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![BU of 6c1h by Molmil](/molmil-images/mine/6c1h) | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6C1D
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![BU of 6c1d by Molmil](/molmil-images/mine/6c1d) | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2MSG
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![BU of 2msg by Molmil](/molmil-images/mine/2msg) | Solid-state NMR structure of ubiquitin | Descriptor: | Ubiquitin | Authors: | Lakomek, N, Habenstein, B, Loquet, A, Shi, C, Giller, K, Wolff, S, Becker, S, Fasshuber, H, Lange, A. | Deposit date: | 2014-08-04 | Release date: | 2015-02-18 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR. Protein Sci., 24, 2015
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2JM8
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![BU of 2jm8 by Molmil](/molmil-images/mine/2jm8) | R21A Spc-SH3 free | Descriptor: | Spectrin alpha chain, brain | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | Deposit date: | 2006-10-25 | Release date: | 2007-04-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3 Bmc Struct.Biol., 7, 2007
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2JMA
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![BU of 2jma by Molmil](/molmil-images/mine/2jma) | R21A Spc-SH3:P41 complex | Descriptor: | P41 peptide, Spectrin alpha chain, brain | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | Deposit date: | 2006-10-25 | Release date: | 2007-04-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3 Bmc Struct.Biol., 7, 2007
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2JM9
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![BU of 2jm9 by Molmil](/molmil-images/mine/2jm9) | R21A Spc-SH3 bound | Descriptor: | Spectrin alpha chain, brain | Authors: | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | Deposit date: | 2006-10-25 | Release date: | 2007-04-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3 Bmc Struct.Biol., 7, 2007
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3FO5
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![BU of 3fo5 by Molmil](/molmil-images/mine/3fo5) | Human START domain of Acyl-coenzyme A thioesterase 11 (ACOT11) | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, CHLORIDE ION, GLYCEROL, ... | Authors: | Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van-Den-Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Shueler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-12-27 | Release date: | 2009-02-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
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4OFH
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4OFE
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![BU of 4ofe by Molmil](/molmil-images/mine/4ofe) | |
4OFA
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![BU of 4ofa by Molmil](/molmil-images/mine/4ofa) | |
7XMS
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![BU of 7xms by Molmil](/molmil-images/mine/7xms) | CryoEM structure of somatostatin receptor 4 (SSTR4) in complex with Gi1 and its endogeneous ligand SST-14 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | Deposit date: | 2022-04-26 | Release date: | 2022-08-03 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7XMR
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![BU of 7xmr by Molmil](/molmil-images/mine/7xmr) | CryoEM structure of the somatostatin receptor 2 (SSTR2) in complex with Gi1 and its endogeneous peptide ligand SST-14 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | Deposit date: | 2022-04-26 | Release date: | 2022-08-03 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7XMT
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![BU of 7xmt by Molmil](/molmil-images/mine/7xmt) | CryoEM structure of somatostatin receptor 4 (SSTR4) with Gi1 and J-2156 | Descriptor: | (2~{S})-2-[[(2~{S})-4-azanyl-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanoyl]amino]-3-phenyl-propanimidic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | Deposit date: | 2022-04-26 | Release date: | 2022-08-03 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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4EUI
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![BU of 4eui by Molmil](/molmil-images/mine/4eui) | Crystal Structure of MIF L46F mutant | Descriptor: | Macrophage migration inhibitory factor, SULFATE ION | Authors: | Ashrafi, A, Pojer, F, Lashuel, H. | Deposit date: | 2012-04-25 | Release date: | 2012-10-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket. Plos One, 7, 2012
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4ETG
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![BU of 4etg by Molmil](/molmil-images/mine/4etg) | Crystal Structure of MIF L46G mutant | Descriptor: | Macrophage migration inhibitory factor, SULFATE ION | Authors: | Ashrafi, A, Pojer, F, Lashuel, H. | Deposit date: | 2012-04-24 | Release date: | 2012-10-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket. Plos One, 7, 2012
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4EVG
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![BU of 4evg by Molmil](/molmil-images/mine/4evg) | Crystal Structure of MIF L46A mutant | Descriptor: | Macrophage migration inhibitory factor, SULFATE ION | Authors: | Ashrafi, A, Pojer, F, Lashuel, H. | Deposit date: | 2012-04-26 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket. Plos One, 7, 2012
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