6MXO
Structure of HPoleta incorporating dCTP opposite the 3-prime Pt(DACH)-GG
Summary for 6MXO
Entry DOI | 10.2210/pdb6mxo/pdb |
Related | 4DL2 4DL3 4DL4 4DL5 |
Descriptor | DNA polymerase eta, DNA (5'-D(*AP*CP*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*G)-3'), ... (8 entities in total) |
Functional Keywords | y-family dna polymerase, pt(dach)-gg, transferase-dna-inhibitor complex, nuclear protein, nuclear protein-dna complex, nuclear protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 56983.14 |
Authors | Ouzon-Shubeita, H.,Lee, S. (deposition date: 2018-10-31, release date: 2019-02-13, Last modification date: 2023-10-11) |
Primary citation | Ouzon-Shubeita, H.,Baker, M.,Koag, M.C.,Lee, S. Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase eta. Biochem. J., 476:747-758, 2019 Cited by PubMed: 30709915DOI: 10.1042/BCJ20180848 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
Download full validation report