5X1A
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![BU of 5x1a by Molmil](/molmil-images/mine/5x1a) | |
8B64
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![BU of 8b64 by Molmil](/molmil-images/mine/8b64) | Cryo-EM structure of RC-LH1-PufX photosynthetic core complex from Rba. capsulatus | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ... | Authors: | Bracun, L, Yamagata, A, Shirouzu, M, Liu, L.N. | Deposit date: | 2022-09-26 | Release date: | 2023-02-01 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (2.589 Å) | Cite: | Cryo-EM structure of a monomeric RC-LH1-PufX supercomplex with high-carotenoid content from Rhodobacter capsulatus. Structure, 31, 2023
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6M04
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![BU of 6m04 by Molmil](/molmil-images/mine/6m04) | Structure of the human homo-hexameric LRRC8D channel at 4.36 Angstroms | Descriptor: | Volume-regulated anion channel subunit LRRC8D | Authors: | Nakamura, R, Kasuya, G, Yokoyama, T, Shirouzu, M, Ishitani, R, Nureki, O. | Deposit date: | 2020-02-20 | Release date: | 2020-06-17 | Method: | ELECTRON MICROSCOPY (4.36 Å) | Cite: | Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation. Commun Biol, 3, 2020
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6AJ4
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![BU of 6aj4 by Molmil](/molmil-images/mine/6aj4) | |
6AJL
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![BU of 6ajl by Molmil](/molmil-images/mine/6ajl) | DOCK7 mutant I1836Y complexed with Cdc42 | Descriptor: | Cell division control protein 42 homolog, Dedicator of cytokinesis protein 7 | Authors: | Kukimoto-Niino, M, Shirouzu, M. | Deposit date: | 2018-08-28 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. Structure, 27, 2019
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1FJD
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![BU of 1fjd by Molmil](/molmil-images/mine/1fjd) | HUMAN PARVULIN-LIKE PEPTIDYL PROLYL CIS/TRANS ISOMERASE, HPAR14 | Descriptor: | PEPTIDYL PROLYL CIS/TRANS ISOMERASE (PPIASE) | Authors: | Terada, T, Shirouzu, M, Fukumori, Y, Fujimori, F, Ito, Y, Kigawa, T, Yokoyama, S, Uchida, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2000-08-08 | Release date: | 2001-08-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the human parvulin-like peptidyl prolyl cis/trans isomerase, hPar14. J.Mol.Biol., 305, 2001
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8HSP
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![BU of 8hsp by Molmil](/molmil-images/mine/8hsp) | E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and t6A37 in classical state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-12-20 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
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8HU1
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![BU of 8hu1 by Molmil](/molmil-images/mine/8hu1) | E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and ct6A37 in classical state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-12-22 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
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8HTZ
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![BU of 8htz by Molmil](/molmil-images/mine/8htz) | E. coli 70S ribosome complexed with H. marismortui tRNA_Ile2 bearing agm2C34 in classical state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-12-22 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
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1GD8
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![BU of 1gd8 by Molmil](/molmil-images/mine/1gd8) | |
6LM1
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![BU of 6lm1 by Molmil](/molmil-images/mine/6lm1) | The crystal structure of cyanorhodopsin (CyR) N4075R from cyanobacteria Tolypothrix sp. NIES-4075 | Descriptor: | DECANE, DODECANE, HEXADECANE, ... | Authors: | Hosaka, T, Kimura-Someya, T, Shirouzu, M. | Deposit date: | 2019-12-24 | Release date: | 2020-10-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A unique clade of light-driven proton-pumping rhodopsins evolved in the cyanobacterial lineage. Sci Rep, 10, 2020
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1EF5
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![BU of 1ef5 by Molmil](/molmil-images/mine/1ef5) | SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF RGL | Descriptor: | RGL | Authors: | Kigawa, T, Endo, M, Ito, Y, Shirouzu, M, Kikuchi, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2000-02-07 | Release date: | 2000-02-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the Ras-binding domain of RGL. FEBS Lett., 441, 1998
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3HJN
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![BU of 3hjn by Molmil](/molmil-images/mine/3hjn) | Crystal structure of thymidylate kinase in complex with dTDP and ADP from Thermotoga maritima | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Yoshikawa, S, Nakagawa, N, Shirouzu, M, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-05-22 | Release date: | 2009-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of thymidylate kinase in complex with dTDP and ADP from Thermotoga maritima To be Published
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8HAM
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![BU of 8ham by Molmil](/molmil-images/mine/8ham) | Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2 | Descriptor: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | Deposit date: | 2022-10-26 | Release date: | 2023-05-17 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAK
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![BU of 8hak by Molmil](/molmil-images/mine/8hak) | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 4 (4.5 angstrom resolution) | Descriptor: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | Deposit date: | 2022-10-26 | Release date: | 2023-05-17 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAI
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![BU of 8hai by Molmil](/molmil-images/mine/8hai) | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (4.7 angstrom resolution) | Descriptor: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | Deposit date: | 2022-10-26 | Release date: | 2023-05-17 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAJ
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![BU of 8haj by Molmil](/molmil-images/mine/8haj) | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (4.8 angstrom resolution) | Descriptor: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | Deposit date: | 2022-10-26 | Release date: | 2023-05-17 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAG
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![BU of 8hag by Molmil](/molmil-images/mine/8hag) | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (3.2 angstrom resolution) | Descriptor: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | Deposit date: | 2022-10-26 | Release date: | 2023-05-17 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAL
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![BU of 8hal by Molmil](/molmil-images/mine/8hal) | Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 1 | Descriptor: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | Deposit date: | 2022-10-26 | Release date: | 2023-05-17 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAN
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![BU of 8han by Molmil](/molmil-images/mine/8han) | Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 3 | Descriptor: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | Deposit date: | 2022-10-26 | Release date: | 2023-05-17 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAH
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![BU of 8hah by Molmil](/molmil-images/mine/8hah) | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (3.9 angstrom resolution) | Descriptor: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | Deposit date: | 2022-10-26 | Release date: | 2023-05-17 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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5CWZ
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![BU of 5cwz by Molmil](/molmil-images/mine/5cwz) | |
5D7A
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![BU of 5d7a by Molmil](/molmil-images/mine/5d7a) | Crystal structure of the kinase domain of TRAF2 and NCK-interacting protein kinase with NCB-0846 | Descriptor: | SULFATE ION, TRAF2 and NCK-interacting protein kinase, cis-4-{[2-(1H-benzimidazol-5-ylamino)quinazolin-8-yl]oxy}cyclohexanol | Authors: | Ohbayashi, N, Kukimoto-Niino, M, Yamada, T, Shirouzu, M. | Deposit date: | 2015-08-13 | Release date: | 2016-08-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | TNIK inhibition abrogates colorectal cancer stemness Nat Commun, 7, 2016
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2KHE
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![BU of 2khe by Molmil](/molmil-images/mine/2khe) | Solution Structure of the Bacterial Toxin Rele from Thermus Thermophilus HB8 | Descriptor: | Toxin-like protein | Authors: | Suzuki, S, Kawazoe, M, Kaminishi, T, Takemoto, C, Muto, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-04-03 | Release date: | 2010-03-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Bacterial Toxin Rele from Thermus Thermophilus HB8 To be Published
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6ACR
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![BU of 6acr by Molmil](/molmil-images/mine/6acr) | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-59638 | Descriptor: | Activin receptor type-1, N-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1H-pyrazol-4-yl]pyrimidin-2-amine, SULFATE ION | Authors: | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | Deposit date: | 2018-07-27 | Release date: | 2019-03-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Bis-Heteroaryl Pyrazoles: Identification of Orally Bioavailable Inhibitors of Activin Receptor-Like Kinase-2 (R206H). Chem. Pharm. Bull., 67, 2019
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