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PDB: 1889 results

5JHL
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Crystal structure of zika virus envelope protein in complex with a flavivirus broadly-protective antibody
Descriptor: Antibody Heavy chain, antibody Light chain, envelope protein
Authors:Dai, L, Shi, Y, Qi, J, Gao, G.F.
Deposit date:2016-04-21
Release date:2016-05-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody.
Cell Host Microbe, 19, 2016
5JHM
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Crystal structure of Zika virus Envelope protein
Descriptor: Envelope protein
Authors:Dai, L, Shi, Y, Qi, J, Gao, G.F.
Deposit date:2016-04-21
Release date:2016-05-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody.
Cell Host Microbe, 19, 2016
5JD0
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BU of 5jd0 by Molmil
crystal structure of ARAP3 RhoGAP domain
Descriptor: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Bao, H, Li, F, Wu, J, Shi, Y.
Deposit date:2016-04-15
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3
J.Biol.Chem., 291, 2016
6J6G
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BU of 6j6g by Molmil
Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom
Descriptor: ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y.
Deposit date:2019-01-15
Release date:2019-04-24
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Cell, 177, 2019
6IYC
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BU of 6iyc by Molmil
Recognition of the Amyloid Precursor Protein by Human gamma-secretase
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhou, R, Yang, G, Guo, X, Zhou, Q, Lei, J, Shi, Y.
Deposit date:2018-12-14
Release date:2019-01-23
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Recognition of the amyloid precursor protein by human gamma-secretase.
Science, 363, 2019
6J6H
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BU of 6j6h by Molmil
Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom
Descriptor: ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y.
Deposit date:2019-01-15
Release date:2019-04-24
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Cell, 177, 2019
6J6N
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BU of 6j6n by Molmil
Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y.
Deposit date:2019-01-15
Release date:2019-04-24
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Cell, 177, 2019
7T0C
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Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2e
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (5S)-5-butyl-4-({1-[(4-chlorophenyl)methyl]-1H-imidazol-5-yl}methyl)-1-[3-(trifluoromethoxy)phenyl]piperazin-2-one, 1,2-ETHANEDIOL, ...
Authors:Wang, Y, Shi, Y, Beese, L.S.
Deposit date:2021-11-29
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
7T0D
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Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2k
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (5S)-4-({1-[(4-bromophenyl)methyl]-1H-imidazol-5-yl}methyl)-5-propyl-1-[3-(trifluoromethoxy)phenyl]piperazin-2-one, 1,2-ETHANEDIOL, ...
Authors:Wang, Y, Shi, Y, Beese, L.S.
Deposit date:2021-11-29
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.906 Å)
Cite:Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
7T0B
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BU of 7t0b by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2g
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (5S)-5-butyl-4-({1-[(4-fluorophenyl)methyl]-1H-imidazol-5-yl}methyl)-1-[3-(trifluoromethoxy)phenyl]piperazin-2-one, 1,2-ETHANEDIOL, ...
Authors:Wang, Y, Shi, Y, Beese, L.S.
Deposit date:2021-11-29
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.026 Å)
Cite:Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
7T0E
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BU of 7t0e by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2b
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (5S)-4-({1-[(4-bromophenyl)methyl]-1H-imidazol-5-yl}methyl)-5-butyl-1-(3-chlorophenyl)piperazin-2-one, 1,2-ETHANEDIOL, ...
Authors:Wang, Y, Shi, Y, Beese, L.S.
Deposit date:2021-11-29
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.223 Å)
Cite:Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
7T0A
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BU of 7t0a by Molmil
Cryptococcus neoformans protein farnesyltransferase co-crystallized with FPP and inhibitor 2f
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (5S)-4-({1-[(4-bromophenyl)methyl]-1H-imidazol-5-yl}methyl)-5-butyl-1-[3-(trifluoromethoxy)phenyl]piperazin-2-one, 1,2-ETHANEDIOL, ...
Authors:Wang, Y, Shi, Y, Beese, L.S.
Deposit date:2021-11-29
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
7T09
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BU of 7t09 by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2d
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 1,2-ETHANEDIOL, 4-{[5-({(2S)-2-butyl-5-oxo-4-[3-(trifluoromethoxy)phenyl]piperazin-1-yl}methyl)-1H-imidazol-1-yl]methyl}benzonitrile, ...
Authors:Wang, Y, Shi, Y, Beese, L.S.
Deposit date:2021-11-29
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.984 Å)
Cite:Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
7T08
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BU of 7t08 by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2q
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 1,2-ETHANEDIOL, 4-{[5-({(2S)-2-butyl-5-oxo-4-[3-(trifluoromethoxy)phenyl]piperazin-1-yl}methyl)-1H-imidazol-1-yl]methyl}-2-fluorobenzonitrile, ...
Authors:Wang, Y, Shi, Y, Beese, L.S.
Deposit date:2021-11-29
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
8E9E
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BU of 8e9e by Molmil
Rat protein farnesyltransferase in complex with FPP and inhibitor 2f
Descriptor: (5S)-4-({1-[(4-bromophenyl)methyl]-1H-imidazol-5-yl}methyl)-5-butyl-1-[3-(trifluoromethoxy)phenyl]piperazin-2-one, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Wang, Y, Shi, Y, Beese, L.S.
Deposit date:2022-08-26
Release date:2022-10-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.844 Å)
Cite:Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
8BW1
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BU of 8bw1 by Molmil
Yeast 20S proteasome in complex with an engineered fellutamide derivative (C14QAL)
Descriptor: 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Bozhueyuek, K.A.J, Praeve, L, Kegler, C, Kaiser, S, Shi, Y, Kuttenlochner, W, Schenk, L, Groll, M, Hochberg, G.K.A, Bode, H.B.
Deposit date:2022-12-06
Release date:2023-12-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Evolution-inspired engineering of nonribosomal peptide synthetases.
Science, 383, 2024
4RHW
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BU of 4rhw by Molmil
Crystal structure of Apaf-1 CARD and caspase-9 CARD complex
Descriptor: Apoptotic protease-activating factor 1, CHLORIDE ION, Caspase-9, ...
Authors:Hu, Q, Wu, D, Yan, C, Shi, Y.
Deposit date:2014-10-03
Release date:2014-10-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome.
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
6IEX
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BU of 6iex by Molmil
Crystal structure of HLA-B*4001 in complex with SARS-CoV derived peptide N216-225 GETALALLLL
Descriptor: Beta-2-microglobulin, GLY-GLU-THR-ALA-LEU-ALA-LEU-LEU-LEU-LEU, MHC class I antigen
Authors:Ji, W, Niu, L, Peng, W, Zhang, Y, Shi, Y, Qi, J, Gao, G.F, Liu, W.J.
Deposit date:2018-09-17
Release date:2019-09-18
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (2.314 Å)
Cite:Salt bridge-forming residues positioned over viral peptides presented by MHC class I impacts T-cell recognition in a binding-dependent manner.
Mol.Immunol., 112, 2019
3GYO
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BU of 3gyo by Molmil
Se-Met Rtt106p
Descriptor: Histone chaperone RTT106
Authors:Liu, Y, Huang, H, Shi, Y, Teng, M.
Deposit date:2009-04-04
Release date:2009-12-08
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural analysis of Rtt106p reveals a DNA-binding role required for heterochromatin silencing
J.Biol.Chem., 285, 2010
3GYP
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BU of 3gyp by Molmil
Rtt106p
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Histone chaperone RTT106
Authors:Liu, Y, Huang, H, Shi, Y, Teng, M.
Deposit date:2009-04-04
Release date:2009-12-08
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Structural analysis of Rtt106p reveals a DNA-binding role required for heterochromatin silencing
J.Biol.Chem., 285, 2010
3JBM
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BU of 3jbm by Molmil
Electron cryo-microscopy of a virus-like particle of orange-spotted grouper nervous necrosis virus
Descriptor: virus-like particle of orange-spotted grouper nervous necrosis virus
Authors:Xie, J, Li, K, Gao, Y, Huang, R, Lai, Y, Shi, Y, Yang, S, Zhu, G, Zhang, Q, He, J.
Deposit date:2015-09-06
Release date:2016-10-19
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural analysis and insertion study reveal the ideal sites for surface displaying foreign peptides on a betanodavirus-like particle
Vet. Res., 47, 2016
3J3T
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BU of 3j3t by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3R
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BU of 3j3r by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
4QY0
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BU of 4qy0 by Molmil
Structure of H10 from human-infecting H10N8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
6DRD
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BU of 6drd by Molmil
RNA Pol II(G)
Descriptor: DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G.
Deposit date:2018-06-11
Release date:2019-06-12
Last modified:2019-12-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.
Nat. Struct. Mol. Biol., 25, 2018

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數據於2024-06-26公開中

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