7BUL
 
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1UFM
 | | Solution structure of the PCI domain | | 分子名称: | COP9 complex subunit 4 | | 著者 | Suzuki, S, Hatanaka, H, Kigawa, T, Shirouzu, M, Hayashizaki, Y, The RIKEN Genome Exploration Research Group Phase I & II Teams, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-02 | | 公開日 | 2004-06-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the PCI domain
To be Published
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7C6A
 | | Crystal structure of AT2R-BRIL and SRP2070_Fab complex | | 分子名称: | IgG Light Chain, IgG heavy chain, SAR1, ... | | 著者 | Suzuki, M, Miyagi, H, Asada, H, Yasunaga, M, Suno, C, Takahashi, Y, Saito, J, Iwata, S. | | 登録日 | 2020-05-21 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | The discovery of a new antibody for BRIL-fused GPCR structure determination.
Sci Rep, 10, 2020
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7C61
 | | Crystal structure of 5-HT1B-BRIL and SRP2070_Fab complex | | 分子名称: | 5-hydroxytryptamine receptor 1B,Soluble cytochrome b562,5-hydroxytryptamine receptor 1B, Ergotamine, IGG HEAVY CHAIN, ... | | 著者 | Suzuki, M, Miyagi, H, Asada, H, Yasunaga, M, Suno, C, Takahashi, Y, Saito, J, Iwata, S. | | 登録日 | 2020-05-21 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The discovery of a new antibody for BRIL-fused GPCR structure determination.
Sci Rep, 10, 2020
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5YLV
 | | Crystal structure of the gastric proton pump complexed with SCH28080 | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(2-methyl-8-phenylmethoxy-imidazo[1,2-a]pyridin-3-yl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | | 登録日 | 2017-10-19 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.79977775 Å) | | 主引用文献 | Crystal structures of the gastric proton pump
Nature, 556, 2018
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3WG7
 | | A 1.9 angstrom radiation damage free X-ray structure of large (420KDa) protein by femtosecond crystallography | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | | 著者 | Hirata, K, Shinzawa-Itoh, K, Yano, N, Takemura, S, Kato, K, Hatanaka, M, Muramoto, K, Kawahara, T, Tsukihara, T, Yamashita, E, Tono, K, Ueno, G, Hikima, T, Murakami, H, Inubushi, Y, Yabashi, M, Ishikawa, T, Yamamoto, M, Ogura, T, Sugimoto, H, Shen, J.R, Yoshikawa, S, Ago, H. | | 登録日 | 2013-07-29 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Determination of damage-free crystal structure of an X-ray-sensitive protein using an XFEL.
Nat.Methods, 11, 2014
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1UHU
 | | Solution structure of the retroviral Gag MA-like domain of RIKEN cDNA 3110009E22 | | 分子名称: | product of RIKEN cDNA 3110009E22 | | 著者 | Suzuki, S, Hatanaka, H, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-07-10 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the retroviral Gag MA-like domain of RIKEN cDNA 3110009E22
To be Published
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5WT5
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5Y0B
 | | PIG GASTRIC H+,K+ - ATPASE IN COMPLEX with BYK99 | | 分子名称: | Potassium-transporting ATPase alpha chain 1, Potassium-transporting ATPase subunit beta | | 著者 | Abe, K, Shimokawa, J, Natio, M, Munson, K, Vagin, O, Sachs, G, Suzuki, H, Tani, K, Fujiyoshi, Y. | | 登録日 | 2017-07-16 | | 公開日 | 2017-08-09 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.7 Å) | | 主引用文献 | The cryo-EM structure of gastric H(+),K(+)-ATPase with bound BYK99, a high-affinity member of K(+)-competitive, imidazo[1,2-a]pyridine inhibitors
Sci Rep, 7, 2017
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7XUD
 | | Structure of G9a in complex with compound 26a | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T. | | 登録日 | 2022-05-18 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
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7XUA
 | | Structure of G9a in complex with compound 10a | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ... | | 著者 | Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T. | | 登録日 | 2022-05-18 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
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7XUC
 | | Structure of G9a in complex with compound 11a | | 分子名称: | 1,2-ETHANEDIOL, 3,6,6-trimethyl-4-oxidanylidene-~{N}-[(2~{S})-1-oxidanylidene-1-phenylazanyl-hexan-2-yl]-5,7-dihydro-1~{H}-indole-2-carboxamide, CHLORIDE ION, ... | | 著者 | Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T. | | 登録日 | 2022-05-18 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
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7XUB
 | | Structure of G9a in complex with compound 10d | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ... | | 著者 | Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T. | | 登録日 | 2022-05-18 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
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5YLU
 | | Crystal structure of the gastric proton pump complexed with vonoprazan | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonyl-pyrrol-3-yl]-~{N}-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | | 登録日 | 2017-10-19 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.79988956 Å) | | 主引用文献 | Crystal structures of the gastric proton pump
Nature, 556, 2018
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7Y51
 | | Acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis TTE0866 delta100 mutant | | 分子名称: | GLYCEROL, NICKEL (II) ION, Predicted xylanase/chitin deacetylase | | 著者 | Sasamoto, K, Himiyama, T, Moriyoshi, K, Ohmoto, T, Uegaki, K, Nakamura, T, Nishiya, Y. | | 登録日 | 2022-06-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Functional analysis of the N-terminal region of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis.
Febs Open Bio, 12, 2022
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5WT6
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7E15
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5WT2
 | | NifS from Helicobacter pylori | | 分子名称: | CHLORIDE ION, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, ... | | 著者 | Fujishiro, T, Takahashi, Y. | | 登録日 | 2016-12-09 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes.
Febs J., 2019
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7EAQ
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5XXN
 | | Crystal Structure of mutant (D286N) beta-glucosidase from Bacteroides thetaiotaomicron in complex with sophorose | | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Periplasmic beta-glucosidase, ... | | 著者 | Nakajima, M, Ishiguro, R, Tanaka, N, Abe, K, Maeda, T, Miyanaga, A, Takahashi, Y, Sugimono, N, Nakai, H, Taguchi, H. | | 登録日 | 2017-07-04 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Function and structure relationships of a beta-1,2-glucooligosaccharide-degrading beta-glucosidase.
FEBS Lett., 591, 2017
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1T7H
 | | X-ray structure of [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide | | 分子名称: | Endothelin-1 | | 著者 | Hoh, F, Cerdan, R, Kaas, Q, Nishi, Y, Chiche, L, Kubo, S, Chino, N, Kobayashi, Y, Dumas, C, Aumelas, A. | | 登録日 | 2004-05-10 | | 公開日 | 2004-12-21 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptide
Biochemistry, 43, 2004
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1WPK
 | | Methylated Form of N-terminal Transcriptional Regulator Domain of Escherichia Coli Ada Protein | | 分子名称: | ADA regulatory protein, ZINC ION | | 著者 | Takinowaki, H, Matsuda, Y, Yoshida, T, Kobayashi, Y, Ohkubo, T. | | 登録日 | 2004-09-07 | | 公開日 | 2005-09-13 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the methylated form of the N-terminal 16-kDa domain of Escherichia coli Ada protein
Protein Sci., 15, 2006
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5XIC
 | | Crystal Structure of HasAp with Fe-5,10,15-triphenylporphyrin | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 5,10,15-Triphenylporphyrin cpntaining FE, Heme acquisition protein HasAp | | 著者 | Shoji, O, Uehara, H, Sugimoto, H, Shiro, Y, Watanabe, Y. | | 登録日 | 2017-04-26 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structures of the Heme Acquisition Protein HasA with Iron(III)-5,15-Diphenylporphyrin and Derivatives Thereof as an Artificial Prosthetic Group
Angew. Chem. Int. Ed. Engl., 56, 2017
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5XIB
 | | Crystal Structure of HasAp with Fe-5,15-Diphenylporphyrin | | 分子名称: | 5,15-Diphenylporphyrin containing FE, Heme acquisition protein HasAp | | 著者 | Shoji, O, Uehara, H, Sugimoto, H, Shiro, Y, Watanabe, Y. | | 登録日 | 2017-04-26 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of the Heme Acquisition Protein HasA with Iron(III)-5,15-Diphenylporphyrin and Derivatives Thereof as an Artificial Prosthetic Group
Angew. Chem. Int. Ed. Engl., 56, 2017
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5X79
 | | Human GST Pi conjugated with novel inhibitor, GS-ESF | | 分子名称: | (2S)-2-azanyl-5-[[(2R)-3-(2-fluorosulfonylethylsulfanyl)-1-(2-hydroxy-2-oxoethylamino)-1-oxidanylidene-propan-2-yl]amino]-5-oxidanylidene-pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutathione S-transferase P | | 著者 | Tomoike, F, Shishido, Y, Fukui, K, Kimura, Y, Abe, H. | | 登録日 | 2017-02-24 | | 公開日 | 2017-09-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A covalent G-site inhibitor for glutathione S-transferase Pi (GSTP1-1).
Chem. Commun. (Camb.), 53, 2017
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