5Y0B
PIG GASTRIC H+,K+ - ATPASE IN COMPLEX with BYK99
Summary for 5Y0B
Entry DOI | 10.2210/pdb5y0b/pdb |
EMDB information | 6799 |
Descriptor | Potassium-transporting ATPase alpha chain 1, Potassium-transporting ATPase subunit beta (2 entities in total) |
Functional Keywords | ion pump, h+, k+-atpase, p-type atpase, membrane protein, hydrolase, e2, aluminium fluoride, atp-binding, hydrogen ion transport, ion transport, magnesium, membrane, metal-binding, nucleotide-binding, phosphoprotein, potassium, potassium transport, transmembrane, transport, disulfide bond, glycoprotein, signal-anchor |
Biological source | Sus scrofa (Pig) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : P19156 Cell membrane ; Single-pass type II membrane protein : P18434 |
Total number of polymer chains | 2 |
Total formula weight | 147513.53 |
Authors | Abe, K.,Shimokawa, J.,Natio, M.,Munson, K.,Vagin, O.,Sachs, G.,Suzuki, H.,Tani, K.,Fujiyoshi, Y. (deposition date: 2017-07-16, release date: 2017-08-09) |
Primary citation | Abe, K.,Shimokawa, J.,Naito, M.,Munson, K.,Vagin, O.,Sachs, G.,Suzuki, H.,Tani, K.,Fujiyoshi, Y. The cryo-EM structure of gastric H(+),K(+)-ATPase with bound BYK99, a high-affinity member of K(+)-competitive, imidazo[1,2-a]pyridine inhibitors Sci Rep, 7:6632-6632, 2017 Cited by PubMed: 28747707DOI: 10.1038/s41598-017-06698-8 PDB entries with the same primary citation |
Experimental method | ELECTRON CRYSTALLOGRAPHY (6.7 Å) |
Structure validation
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