5WZQ
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![BU of 5wzq by Molmil](/molmil-images/mine/5wzq) | Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - quadruple mutant | 分子名称: | Alpha-N-acetylgalactosaminidase, GLYCEROL, ZINC ION | 著者 | Sato, M, Arakawa, T, Ashida, H, Fushinobu, S. | 登録日 | 2017-01-18 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors J. Biol. Chem., 292, 2017
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5EF9
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4MW2
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![BU of 4mw2 by Molmil](/molmil-images/mine/4mw2) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1472) | 分子名称: | 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2013-09-24 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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7E5V
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![BU of 7e5v by Molmil](/molmil-images/mine/7e5v) | Crystal structure of Phm7 in complex with inhibitor | 分子名称: | Diels-Alderase, GLYCEROL, SULFATE ION, ... | 著者 | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | 登録日 | 2021-02-20 | 公開日 | 2021-06-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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7E5U
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![BU of 7e5u by Molmil](/molmil-images/mine/7e5u) | Crystal structure of Phm7 | 分子名称: | CHLORIDE ION, Diels-Alderase, GLYCEROL, ... | 著者 | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | 登録日 | 2021-02-20 | 公開日 | 2021-06-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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7E5T
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![BU of 7e5t by Molmil](/molmil-images/mine/7e5t) | Crystal structure of Fsa2 | 分子名称: | Diels-Alderase fsa2, ETHANOL, PENTAETHYLENE GLYCOL, ... | 著者 | Fujiyama, K, Kato, N, Kinugasa, K, Hino, T, Takahashi, S, Nagano, S. | 登録日 | 2021-02-20 | 公開日 | 2021-06-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.16977525 Å) | 主引用文献 | Molecular Basis for Two Stereoselective Diels-Alderases that Produce Decalin Skeletons*. Angew.Chem.Int.Ed.Engl., 60, 2021
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4MW7
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![BU of 4mw7 by Molmil](/molmil-images/mine/4mw7) | Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1469) | 分子名称: | 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2013-09-24 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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4GVS
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![BU of 4gvs by Molmil](/molmil-images/mine/4gvs) | X-ray structure of the Archaeoglobus fulgidus methenyl-tetrahydromethanopterin cyclohydrolase in complex with N5-formyl-tetrahydromethanopterin | 分子名称: | 1-[4-({(1R)-1-[(6S,7R)-2-amino-5-formyl-7-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]ethyl}amino)phenyl]-1-deoxy-5 -O-{5-O-[(R)-{[(1R)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol, Methenyltetrahydromethanopterin cyclohydrolase | 著者 | Upadhyay, V, Demmer, U, Warkentin, E, Moll, J, Shima, S, Ermler, U. | 登録日 | 2012-08-31 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure and catalytic mechanism of N(5),N(10)-methenyl-tetrahydromethanopterin cyclohydrolase. Biochemistry, 51, 2012
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5YGX
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![BU of 5ygx by Molmil](/molmil-images/mine/5ygx) | Structure of BACE1 in complex with N-(3-((4R,5R,6S)-2-amino-6-(1,1-difluoroethyl)-5-fluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide | 分子名称: | Beta-secretase 1, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Nakahara, K, Fuchino, K, Komano, K, Asada, N, Tadano, G, Hasegawa, T, Yamamoto, T, Sako, Y, Ogawa, M, Unemura, C, Hosono, M, Sakaguchi, G, Ando, S, Ohnishi, S, Kido, Y, Fukushima, T, Dhuyvetter, D, Borghys, H, Gijsen, H, Yamano, Y, Iso, Y, Kusakabe, K. | 登録日 | 2017-09-27 | 公開日 | 2018-08-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of Potent and Centrally Active 6-Substituted 5-Fluoro-1,3-dihydro-oxazine beta-Secretase (BACE1) Inhibitors via Active Conformation Stabilization J. Med. Chem., 61, 2018
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4JJG
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![BU of 4jjg by Molmil](/molmil-images/mine/4jjg) | Crystal structure of FE-hydrogenase from methanothermobacter marburgensis in complex with toluenesulfonylmethylisocyanide | 分子名称: | 5,10-methenyltetrahydromethanopterin hydrogenase, N-methyl-1-[(4-methylbenzyl)sulfonyl]methanamine, iron-guanylyl pyridinol cofactor | 著者 | Tamura, H, Warkentin, E, Ermler, U, Shima, S. | 登録日 | 2013-03-07 | 公開日 | 2013-08-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of [fe]-hydrogenase in complex with inhibitory isocyanides: implications for the h2 -activation site. Angew.Chem.Int.Ed.Engl., 52, 2013
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5EFA
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2KFJ
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![BU of 2kfj by Molmil](/molmil-images/mine/2kfj) | Solution structure of the loop deletion mutant of PB1 domain of Cdc24p | 分子名称: | Cell division control protein 24 | 著者 | Ogura, K, Tandai, T, Yoshinaga, S, Kobashigawa, Y, Kumeta, H, Inagaki, F. | 登録日 | 2009-02-22 | 公開日 | 2009-10-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae J.Biochem., 146, 2009
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4KTP
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![BU of 4ktp by Molmil](/molmil-images/mine/4ktp) | Crystal structure of 2-O-alpha-glucosylglycerol phosphorylase in complex with glucose | 分子名称: | CALCIUM ION, Glycoside hydrolase family 65 central catalytic, PENTAETHYLENE GLYCOL, ... | 著者 | Touhara, K.K, Nihira, T, Kitaoka, M, Nakai, H, Fushinobu, S. | 登録日 | 2013-05-21 | 公開日 | 2014-05-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for reversible phosphorolysis and hydrolysis reactions of 2-O-alpha-glucosylglycerol phosphorylase J.Biol.Chem., 289, 2014
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5EFC
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3WJ2
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![BU of 3wj2 by Molmil](/molmil-images/mine/3wj2) | Crystal structure of ESTFA (FE-lacking apo form) | 分子名称: | Carboxylesterase | 著者 | Ohara, K, Unno, H, Oshima, Y, Furukawa, K, Fujino, N, Hirooka, K, Hemmi, H, Takahashi, S, Nishino, T, Kusunoki, M, Nakayama, T. | 登録日 | 2013-10-03 | 公開日 | 2014-07-30 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Structural insights into the low pH adaptation of a unique carboxylesterase from Ferroplasma: altering the pH optima of two carboxylesterases. J.Biol.Chem., 289, 2014
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7DIF
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![BU of 7dif by Molmil](/molmil-images/mine/7dif) | GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with beta-L-arabinofuranose-configured cyclophellitol at 1.75-angstrom resolution | 分子名称: | (1S,2S,3R,4R)-3-(hydroxymethyl)cyclopentane-1,2,4-triol, Non-reducing end beta-L-arabinofuranosidase, POTASSIUM ION, ... | 著者 | Amaki, S, McGregor, N.G.S, Arakawa, T, Yamada, C, Borlandelli, V, Overkleeft, H.S, Davies, G.J, Fushinobu, S. | 登録日 | 2020-11-19 | 公開日 | 2021-01-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent beta-l-Arabinofuranosidase Inhibitor. Angew.Chem.Int.Ed.Engl., 60, 2021
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1J26
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![BU of 1j26 by Molmil](/molmil-images/mine/1j26) | Solution structure of a putative peptidyl-tRNA hydrolase domain in a mouse hypothetical protein | 分子名称: | immature colon carcinoma transcript 1 | 著者 | Nameki, N, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-12-25 | 公開日 | 2004-06-01 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the catalytic domain of the mitochondrial protein ICT1 that is essential for cell vitality J.Mol.Biol., 2010
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1IYR
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![BU of 1iyr by Molmil](/molmil-images/mine/1iyr) | NMR Structure Ensemble Of Dff-C Domain | 分子名称: | DNA FRAGMENTATION FACTOR ALPHA SUBUNIT | 著者 | Fukushima, K, Kikuchi, J, Koshiba, S, Kigawa, T, Kuroda, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-09-05 | 公開日 | 2002-09-25 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Dff-C Domain of Dff45/Icad. A Structural Basis for the Regulation of Apoptotic DNA Fragmentation J.Mol.Biol., 321, 2002
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1J0F
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![BU of 1j0f by Molmil](/molmil-images/mine/1j0f) | Solution Structure of the SH3 Domain Binding Glutamic Acid-rich Protein Like 3 | 分子名称: | SH3 domain-binding glutamic acid-rich-like protein 3 | 著者 | Miyamoto, K, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-11-12 | 公開日 | 2003-12-02 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the SH3 Domain Binding Glutamic Acid-rich Protein Like 3 To be Published
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1IQA
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![BU of 1iqa by Molmil](/molmil-images/mine/1iqa) | CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MOUSE RANK LIGAND | 分子名称: | RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND | 著者 | Ito, S, Wakabayashi, K, Ubukata, O, Hayashi, S, Okada, F, Hata, T. | 登録日 | 2001-07-11 | 公開日 | 2002-03-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution. J.Biol.Chem., 277, 2002
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5FW4
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![BU of 5fw4 by Molmil](/molmil-images/mine/5fw4) | Structure of Thermobifida fusca DyP-type Peroxidase and Activity towards Kraft Lignin and Lignin Model Compounds | 分子名称: | DYE-DECOLORIZING PEROXIDASE TFU_3078, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Rahmanpour, R, Rea, D, Jamshidi, S, Fulop, V, Bugg, T.D.H. | 登録日 | 2016-02-11 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of Thermobifida Fusca Dyp-Type Peroxidase and Activity Towards Kraft Lignin and Lignin Model Compounds. Arch.Biochem.Biophys., 594, 2016
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4KTR
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![BU of 4ktr by Molmil](/molmil-images/mine/4ktr) | Crystal structure of 2-O-alpha-glucosylglycerol phosphorylase in complex with isofagomine and glycerol | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... | 著者 | Touhara, K.K, Nihira, T, Kitaoka, M, Nakai, H, Fushinobu, S. | 登録日 | 2013-05-21 | 公開日 | 2014-05-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for reversible phosphorolysis and hydrolysis reactions of 2-O-alpha-glucosylglycerol phosphorylase J.Biol.Chem., 289, 2014
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2KFK
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![BU of 2kfk by Molmil](/molmil-images/mine/2kfk) | Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain | 分子名称: | Bud emergence protein 1, Cell division control protein 24 | 著者 | Kobashigawa, Y, Yoshinaga, S, Tandai, T, Ogura, K, Inagaki, F. | 登録日 | 2009-02-23 | 公開日 | 2009-10-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae J.Biochem., 146, 2009
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4GVQ
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![BU of 4gvq by Molmil](/molmil-images/mine/4gvq) | X-ray structure of the Archaeoglobus fulgidus methenyl-tetrahydromethanopterin cyclohydrolase in complex with tetrahydromethanpterin | 分子名称: | 1-[4-({(1R)-1-[(6S,7S)-2-amino-7-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]ethyl}amino)phenyl]-1-deoxy-5-O-{5-O-[(R)-{[(1R)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-xylitol, Methenyltetrahydromethanopterin cyclohydrolase | 著者 | Upadhyay, V, Demmer, U, Warkentin, E, Moll, J, Shima, S, Ermler, U. | 登録日 | 2012-08-31 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structure and catalytic mechanism of N(5),N(10)-methenyl-tetrahydromethanopterin cyclohydrolase. Biochemistry, 51, 2012
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4GVR
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![BU of 4gvr by Molmil](/molmil-images/mine/4gvr) | X-ray structure of the Archaeoglobus fulgidus methenyl-tetrahydromethanopterin cyclohydrolase | 分子名称: | Methenyltetrahydromethanopterin cyclohydrolase | 著者 | Upadhyay, V, Demmer, U, Warkentin, E, Moll, J, Shima, S, Ermler, U. | 登録日 | 2012-08-31 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Structure and catalytic mechanism of N(5),N(10)-methenyl-tetrahydromethanopterin cyclohydrolase. Biochemistry, 51, 2012
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