7DIF

GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with beta-L-arabinofuranose-configured cyclophellitol at 1.75-angstrom resolution

Summary for 7DIF

Entry DOI	10.2210/pdb7dif/pdb
Descriptor	Non-reducing end beta-L-arabinofuranosidase, ZINC ION, (1S,2S,3R,4R)-3-(hydroxymethyl)cyclopentane-1,2,4-triol, ... (5 entities in total)
Functional Keywords	(alpha/alpha)6 barrel, glycoside hydrolase family 127, hydrolase
Biological source	Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)
Total number of polymer chains	1
Total formula weight	74710.57
Authors	Amaki, S.,McGregor, N.G.S.,Arakawa, T.,Yamada, C.,Borlandelli, V.,Overkleeft, H.S.,Davies, G.J.,Fushinobu, S. (deposition date: 2020-11-19, release date: 2021-01-27, Last modification date: 2023-11-29)
Primary citation	McGregor, N.G.S.,Coines, J.,Borlandelli, V.,Amaki, S.,Artola, M.,Nin-Hill, A.,Linzel, D.,Yamada, C.,Arakawa, T.,Ishiwata, A.,Ito, Y.,van der Marel, G.A.,Codee, J.D.C.,Fushinobu, S.,Overkleeft, H.S.,Rovira, C.,Davies, G.J. Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent beta-l-Arabinofuranosidase Inhibitor. Angew.Chem.Int.Ed.Engl., 60:5754-5758, 2021 Cited by PubMed: 33528085 DOI: 10.1002/anie.202013920 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation