5AWW
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![BU of 5aww by Molmil](/molmil-images/mine/5aww) | Precise Resting State of Thermus thermophilus SecYEG | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Protein translocase subunit SecE, Protein translocase subunit SecY, ... | 著者 | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | 登録日 | 2015-07-10 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.724 Å) | 主引用文献 | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State. Cell Rep, 13, 2015
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5CH4
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![BU of 5ch4 by Molmil](/molmil-images/mine/5ch4) | Peptide-Bound State of Thermus thermophilus SecYEG | 分子名称: | Protein translocase subunit SecE, Protein translocase subunit SecY, Putative preprotein translocase, ... | 著者 | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | 登録日 | 2015-07-10 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | 主引用文献 | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State. Cell Rep, 13, 2015
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1JAJ
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6A28
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![BU of 6a28 by Molmil](/molmil-images/mine/6a28) | Crystal structure of PprA W183R mutant form 2 | 分子名称: | DNA repair protein PprA, SULFATE ION | 著者 | Adachi, M, Shibazaki, C, Shimizu, R, Arai, S, Satoh, K, Narumi, I, Kuroki, R. | 登録日 | 2018-06-09 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.193 Å) | 主引用文献 | Extended structure of pleiotropic DNA repair-promoting protein PprA from Deinococcus radiodurans. FASEB J., 33, 2019
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2E8A
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![BU of 2e8a by Molmil](/molmil-images/mine/2e8a) | Crystal structure of the human Hsp70 ATPase domain in complex with AMP-PNP | 分子名称: | Heat shock 70kDa protein 1A, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Shida, M, Ishii, R, Takagi, T, Kishishita, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-01-19 | 公開日 | 2008-01-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state. Acta Crystallogr.,Sect.D, 66, 2010
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8GOS
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2E88
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![BU of 2e88 by Molmil](/molmil-images/mine/2e88) | Crystal structure of the human Hsp70 ATPase domain in the apo form | 分子名称: | Heat shock 70kDa protein 1A, ZINC ION | 著者 | Shida, M, Ishii, R, Takagi, T, Kishishita, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-01-19 | 公開日 | 2008-01-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state. Acta Crystallogr.,Sect.D, 66, 2010
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5Y78
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![BU of 5y78 by Molmil](/molmil-images/mine/5y78) | Crystal structure of the triose-phosphate/phosphate translocator in complex with inorganic phosphate | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PHOSPHATE ION, Putative hexose phosphate translocator | 著者 | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | 登録日 | 2017-08-16 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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5Y79
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![BU of 5y79 by Molmil](/molmil-images/mine/5y79) | Crystal structure of the triose-phosphate/phosphate translocator in complex with 3-phosphoglycerate | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-PHOSPHOGLYCERIC ACID, CITRATE ANION, ... | 著者 | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | 登録日 | 2017-08-16 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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8HUK
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![BU of 8huk by Molmil](/molmil-images/mine/8huk) | X-ray structure of human PPAR alpha ligand binding domain-lanifibranor-SRC1 coactivator peptide co-crystals obtained by soaking | 分子名称: | 15-meric peptide from Nuclear receptor coactivator 1, 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl]butanoic acid, Peroxisome proliferator-activated receptor alpha | 著者 | Kamata, S, Ishikawa, R, Akahane, M, Honda, A, Oyama, T, Ishii, I. | 登録日 | 2022-12-24 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.981 Å) | 主引用文献 | Functional and Structural Insights into the Human PPAR alpha / delta / gamma Targeting Preferences of Anti-NASH Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor. Antioxidants, 12, 2023
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8HUQ
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![BU of 8huq by Molmil](/molmil-images/mine/8huq) | X-ray structure of human PPAR alpha ligand binding domain-elafibranor-SRC1 coactivator peptide co-crystals obtained by soaking | 分子名称: | 15-meric peptide from Nuclear receptor coactivator 1, 2-[2,6-dimethyl-4-[(~{E})-3-(4-methylsulfanylphenyl)-3-oxidanylidene-prop-1-enyl]phenoxy]-2-methyl-propanoic acid, GLYCEROL, ... | 著者 | Kamata, S, Ishikawa, R, Akahane, M, Honda, A, Oyama, T, Ishii, I. | 登録日 | 2022-12-24 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Functional and Structural Insights into the Human PPAR alpha / delta / gamma Targeting Preferences of Anti-NASH Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor. Antioxidants, 12, 2023
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4MKP
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![BU of 4mkp by Molmil](/molmil-images/mine/4mkp) | Crystal structure of human cGAS apo form | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION | 著者 | Kato, K, Ishii, R, Ishitani, R, Nureki, O. | 登録日 | 2013-09-05 | 公開日 | 2013-10-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.953 Å) | 主引用文献 | Structural and Functional Analyses of DNA-Sensing and Immune Activation by Human cGAS Plos One, 8, 2013
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3CAF
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4L3O
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![BU of 4l3o by Molmil](/molmil-images/mine/4l3o) | Crystal Structure of SIRT2 in complex with the macrocyclic peptide S2iL5 | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NAD-dependent protein deacetylase sirtuin-2, ... | 著者 | Yamagata, K, Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2013-06-06 | 公開日 | 2014-02-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.518 Å) | 主引用文献 | Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change Structure, 22, 2013
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6JMQ
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![BU of 6jmq by Molmil](/molmil-images/mine/6jmq) | LAT1-CD98hc complex bound to MEM-108 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | 著者 | Lee, Y, Nishizawa, T, Kusakizako, T, Oda, K, Ishitani, R, Nakane, T, Nureki, O. | 登録日 | 2019-03-13 | 公開日 | 2019-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nat.Struct.Mol.Biol., 26, 2019
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3CU1
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![BU of 3cu1 by Molmil](/molmil-images/mine/3cu1) | Crystal Structure of 2:2:2 FGFR2D2:FGF1:SOS complex | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor receptor 2, Heparin-binding growth factor 1 | 著者 | Guo, F, Dakshinamurthy, R, Thallapuranam, S.K.K, Sakon, J. | 登録日 | 2008-04-15 | 公開日 | 2009-04-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of 2:2:2 FGFR2D2:FGF1:SOS complex To be Published
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7CT4
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![BU of 7ct4 by Molmil](/molmil-images/mine/7ct4) | Crystal structure of D-amino acid oxidase from Rasamsonia emersonii strain YA | 分子名称: | D-amino acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Shimekake, Y, Hirato, Y, Okazaki, S, Funabashi, R, Goto, M, Furuichi, T, Suzuki, H, Takahashi, S. | 登録日 | 2020-08-18 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structure analysis of a unique D-amino-acid oxidase from the thermophilic fungus Rasamsonia emersonii strain YA. Acta Crystallogr.,Sect.F, 76, 2020
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5EGE
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![BU of 5ege by Molmil](/molmil-images/mine/5ege) | Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Morita, J, Kano, K, Kato, K, Takita, H, Ishitani, R, Nishimasu, H, Nureki, O, Aoki, J. | 登録日 | 2015-10-27 | 公開日 | 2016-03-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase Sci Rep, 6, 2016
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1IZR
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![BU of 1izr by Molmil](/molmil-images/mine/1izr) | F46A mutant of bovine pancreatic ribonuclease A | 分子名称: | RIBONUCLEASE A | 著者 | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | 登録日 | 2002-10-11 | 公開日 | 2003-11-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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5GUH
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![BU of 5guh by Molmil](/molmil-images/mine/5guh) | Crystal structure of silkworm PIWI-clade Argonaute Siwi bound to piRNA | 分子名称: | MAGNESIUM ION, PIWI, RNA (28-MER) | 著者 | Matsumoto, N, Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2016-08-29 | 公開日 | 2016-10-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA Cell, 167, 2016
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5EGH
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![BU of 5egh by Molmil](/molmil-images/mine/5egh) | Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in complex with phosphocholine | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Morita, J, Kano, K, Kato, K, Takita, H, Ishitani, R, Nishimasu, H, Nureki, O, Aoki, J. | 登録日 | 2015-10-27 | 公開日 | 2016-03-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase Sci Rep, 6, 2016
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5GIJ
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![BU of 5gij by Molmil](/molmil-images/mine/5gij) | Crystal structure of TDR-TDIF complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat receptor-like protein kinase TDR, ... | 著者 | Morita, J, Kato, K, Ishitani, R, Nishimasu, H, Nureki, O. | 登録日 | 2016-06-23 | 公開日 | 2016-08-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide Nat Commun, 7, 2016
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1IZQ
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![BU of 1izq by Molmil](/molmil-images/mine/1izq) | F46V mutant of bovine pancreatic ribonuclease A | 分子名称: | RIBONUCLEASE A | 著者 | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | 登録日 | 2002-10-11 | 公開日 | 2003-11-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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1JSA
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![BU of 1jsa by Molmil](/molmil-images/mine/1jsa) | MYRISTOYLATED RECOVERIN WITH TWO CALCIUMS BOUND, NMR, 24 STRUCTURES | 分子名称: | CALCIUM ION, MYRISTIC ACID, RECOVERIN | 著者 | Ames, J.B, Ishima, R, Tanaka, T, Gordon, J.I, Stryer, L, Ikura, M. | 登録日 | 1997-06-04 | 公開日 | 1997-10-15 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular mechanics of calcium-myristoyl switches. Nature, 389, 1997
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5HP5
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![BU of 5hp5 by Molmil](/molmil-images/mine/5hp5) | Srtucture of human peptidylarginine deiminase type I (PAD1) | 分子名称: | CALCIUM ION, Protein-arginine deiminase type-1 | 著者 | Unno, M, Nagai, A, Saijo, S, Shimizu, N, Kinjo, S, Mashimo, R, Kizawa, K, Takahara, H. | 登録日 | 2016-01-20 | 公開日 | 2016-07-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.198 Å) | 主引用文献 | Monomeric Form of Peptidylarginine Deiminase Type I Revealed by X-ray Crystallography and Small-Angle X-ray Scattering J.Mol.Biol., 428, 2016
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