2E8A
Crystal structure of the human Hsp70 ATPase domain in complex with AMP-PNP
Summary for 2E8A
Entry DOI | 10.2210/pdb2e8a/pdb |
Related | 2E88 |
Descriptor | Heat shock 70kDa protein 1A, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | hydrolase, anp, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 43624.21 |
Authors | Shida, M.,Ishii, R.,Takagi, T.,Kishishita, S.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-01-19, release date: 2008-01-22, Last modification date: 2023-10-25) |
Primary citation | Shida, M.,Arakawa, A.,Ishii, R.,Kishishita, S.,Takagi, T.,Kukimoto-Niino, M.,Sugano, S.,Tanaka, A.,Shirouzu, M.,Yokoyama, S. Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state. Acta Crystallogr.,Sect.D, 66:223-232, 2010 Cited by PubMed: 20179333DOI: 10.1107/S0907444909053979 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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