2E8A
Crystal structure of the human Hsp70 ATPase domain in complex with AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock 70kDa protein 1A | polymer | 391 | 43093.7 | 1 | UniProt (Q5JQI4) Pfam (PF00012) UniProt (by SIFTS) (P0DMV8) | Homo sapiens (human) | chaperon protein, Heat shock 70kDa protein 1B |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) PubChem (4795) PubChem (33113) PubChem (445863) PubChem (6102784) PubChem (9543492) PubChem (14188278) PubChem (16058657) PubChem (23639785) PubChem (24794410) PubChem (44462678) PubChem (46926537) PubChem (54765332) PubChem (60063697) PubChem (66575078) PubChem (89688694) PubChem (92436779) PubChem (93005803) | |||
| 4 | D (A) | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
A: 1 - 388 (UniProt: Q5JQI4)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43093.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 530.5 | |
| All* | Total formula weight | 43624.2 |
