2E8A
Crystal structure of the human Hsp70 ATPase domain in complex with AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock 70kDa protein 1A | polymer | 391 | 43093.7 | 1 | UniProt (Q5JQI4) Pfam (PF00012) UniProt (by SIFTS) (P0DMV8) | Homo sapiens (human) | chaperon protein, Heat shock 70kDa protein 1B |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 4 | D (A) | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
A: 1 - 388 (UniProt: Q5JQI4)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43093.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 530.5 | |
| All* | Total formula weight | 43624.2 |
