5B2S
 
 | | Crystal structure of the Streptococcus pyogenes Cas9 EQR variant in complex with sgRNA and target DNA (TGAG PAM) | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | 登録日 | 2016-02-02 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
Mol.Cell, 61, 2016
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5AXV
 | | Crystal Structure of Cypovirus Polyhedra R13K Mutant | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Abe, S, Ijiri, H, Negishi, H, Yamanaka, H, Sasaki, K, Hirata, K, Mori, H, Ueno, T. | | 登録日 | 2015-08-01 | | 公開日 | 2015-11-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Design of Enzyme-Encapsulated Protein Containers by In Vivo Crystal Engineering
Adv. Mater. Weinheim, 27, 2015
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5B2R
 | | Crystal structure of the Streptococcus pyogenes Cas9 VQR variant in complex with sgRNA and target DNA (TGA PAM) | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | 登録日 | 2016-02-02 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
Mol.Cell, 61, 2016
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5AXU
 | | Crystal Structure of Cypovirus Polyhedra R13A Mutant | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Abe, S, Ijiri, H, Negishi, H, Yamanaka, H, Sasaki, K, Hirata, K, Mori, H, Ueno, T. | | 登録日 | 2015-08-01 | | 公開日 | 2015-11-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Design of Enzyme-Encapsulated Protein Containers by In Vivo Crystal Engineering
Adv. Mater. Weinheim, 27, 2015
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7C86
 | | Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin: Dark state structure | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RETINAL, ... | | 著者 | Oda, K, Nomura, T, Nakane, T, Yamashita, K, Inoue, K, Ito, S, Vierock, J, Hirata, K, Maturana, A.D, Katayama, K, Ikuta, T, Ishigami, I, Izume, T, Umeda, R, Eguma, R, Oishi, S, Kasuya, G, Kato, T, Kusakizako, T, Shihoya, W, Shimada, H, Takatsuji, T, Takemoto, M, Taniguchi, R, Tomita, A, Nakamura, R, Fukuda, M, Miyauchi, H, Lee, Y, Nango, E, Tanaka, R, Tanaka, T, Sugahara, M, Kimura, T, Shimamura, T, Fujiwara, T, Yamanaka, Y, Owada, S, Joti, Y, Tono, K, Ishitani, R, Hayashi, S, Kandori, H, Hegemann, P, Iwata, S, Kubo, M, Nishizawa, T, Nureki, O. | | 登録日 | 2020-05-28 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin.
Elife, 10, 2021
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1C7Y
 | | E.COLI RUVA-HOLLIDAY JUNCTION COMPLEX | | 分子名称: | DNA (5'-D(P*DAP*DAP*DGP*DTP*DTP*DGP*DGP*DGP*DAP*DTP*DTP*DGP*DT)-3'), DNA (5'-D(P*DCP*DAP*DAP*DTP*DCP*DCP*DCP*DAP*DAP*DCP*DTP*DT)-3'), DNA (5'-D(P*DCP*DGP*DAP*DAP*DTP*DGP*DTP*DGP*DTP*DGP*DTP*DCP*DT)-3'), ... | | 著者 | Ariyoshi, M, Nishino, T, Iwasaki, H, Shinagawa, H, Morikawa, K. | | 登録日 | 2000-04-03 | | 公開日 | 2000-07-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of the holliday junction DNA in complex with a single RuvA tetramer.
Proc.Natl.Acad.Sci.USA, 97, 2000
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2RU7
 | | Refined structure of RNA aptamer in complex with the partial binding peptide of prion protein | | 分子名称: | P16 peptide from Major prion protein, RNA_(5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3') | | 著者 | Hayashi, T, Oshima, H, Mashima, T, Nagata, T, Katahira, M, Kinoshita, M. | | 登録日 | 2013-12-24 | | 公開日 | 2014-05-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition.
Nucleic Acids Res., 42, 2014
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5KVB
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7T3P
 | | IP3 and ATP bound type 3 IP3 receptor in the pre-active A state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | | 登録日 | 2021-12-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for activation and gating of IP 3 receptors.
Nat Commun, 13, 2022
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7T3Q
 | | IP3 and ATP bound type 3 IP3 receptor in the pre-active B state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | | 登録日 | 2021-12-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for activation and gating of IP 3 receptors.
Nat Commun, 13, 2022
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7T3T
 | | IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the active state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | | 登録日 | 2021-12-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis for activation and gating of IP 3 receptors.
Nat Commun, 13, 2022
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7T3U
 | | IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the inactive state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | | 登録日 | 2021-12-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for activation and gating of IP 3 receptors.
Nat Commun, 13, 2022
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7T3R
 | | IP3 and ATP bound type 3 IP3 receptor in the pre-active C state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | | 著者 | Schmitz, E.A, Takahashi, H, Karakas, E. | | 登録日 | 2021-12-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for activation and gating of IP 3 receptors.
Nat Commun, 13, 2022
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4H2P
 | | Tetrameric form of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO) | | 分子名称: | 1,2-ETHANEDIOL, 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, BETA-MERCAPTOETHANOL, ... | | 著者 | Kobayashi, J, Yoshida, H, Mikami, B, Hayashi, H, Kamitori, S, Yagi, T. | | 登録日 | 2012-09-13 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
To be Published
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8WUW
 | | Cryo-EM structure of H. thermophilus GroEL-GroES2 asymmetric football complex | | 分子名称: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | | 登録日 | 2023-10-21 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into thermophilic chaperonin complexes.
Structure, 32, 2024
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8WUX
 | | Cryo-EM structure of H. thermophilus GroEL-GroES bullet complex | | 分子名称: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | | 登録日 | 2023-10-21 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into thermophilic chaperonin complexes.
Structure, 32, 2024
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8WU4
 | | Cryo-EM structure of native H. thermoluteolus TH-1 GroEL | | 分子名称: | Chaperonin GroEL | | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | | 登録日 | 2023-10-20 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into thermophilic chaperonin complexes.
Structure, 32, 2024
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8J12
 | | Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex | | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (247-MER), ... | | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | | 登録日 | 2023-04-12 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis.
Cell, 186, 2023
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8J3R
 | | Cryo-EM structure of the AsCas12f-HKRA-sgRNAS3-5v7-target DNA | | 分子名称: | DNA (37-MER), DNA (38-MER), MAGNESIUM ION, ... | | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | | 登録日 | 2023-04-18 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis.
Cell, 186, 2023
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8J1J
 | | Cryo-EM structure of the AsCas12f-YHAM-sgRNAS3-5v7-target DNA | | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (118-MER), ... | | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | | 登録日 | 2023-04-13 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis.
Cell, 186, 2023
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4H2R
 | | Structure of MHPCO Y270F mutant, 5-hydroxynicotinic acid complex | | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxypyridine-3-carboxylic acid, BETA-MERCAPTOETHANOL, ... | | 著者 | Kobayashi, J, Yoshida, H, Mikami, B, Hayashi, H, Kamitori, S, Yagi, T. | | 登録日 | 2012-09-13 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.473 Å) | | 主引用文献 | Crystal structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
To be Published
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7X7O
 | | SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K | | 分子名称: | Spike protein S1, UT28K Fab, heavy chain, ... | | 著者 | Ozawa, T, Tani, H, Anraku, Y, Kita, S, Igarashi, E, Saga, Y, Inasaki, N, Kawasuji, H, Yamada, H, Sasaki, S, Somekawa, M, Sasaki, J, Hayakawa, Y, Yamamoto, Y, Morinaga, Y, Kurosawa, N, Isobe, M, Fukuhara, H, Maenaka, K, Hashiguchi, T, Kishi, H, Kitajima, I, Saito, S, Niimi, H. | | 登録日 | 2022-03-10 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | | 主引用文献 | Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants.
Mabs, 14, 2022
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4GF7
 | | Crystal structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO), unliganded form | | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kobayashi, J, Yoshida, H, Mikami, B, Hayashi, H, Kamitori, S, Sawa, Y, Yagi, T. | | 登録日 | 2012-08-03 | | 公開日 | 2013-08-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.581 Å) | | 主引用文献 | Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
To be Published
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4H2N
 | | Crystal structure of MHPCO, Y270F mutant | | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, BETA-MERCAPTOETHANOL, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Kobayashi, J, Yoshida, H, Mikami, B, Hayashi, H, Kamitori, S, Yagi, T. | | 登録日 | 2012-09-12 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase
To be Published
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4H2Q
 | | structure of MHPCO-5HN complex | | 分子名称: | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxypyridine-3-carboxylic acid, BETA-MERCAPTOETHANOL, ... | | 著者 | Kobayashi, J, Yoshida, H, Mikami, B, Hayashi, H, Kamitori, S, Yagi, T. | | 登録日 | 2012-09-13 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | | 主引用文献 | Crystal structure of 2-Methyl-3-hydroxypyridiine-5-carboxylic acid oxygenase
To be Published
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