2RU7

Refined structure of RNA aptamer in complex with the partial binding peptide of prion protein

Summary for 2RU7

• Entry DOI: 10.2210/pdb2ru7/pdb
• Related: 2RSK
• NMR Information: BMRB: 11489
• Descriptor: RNA_(5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'), P16 peptide from Major prion protein (2 entities in total)
• Functional Keywords: aptamer, prion, rna, alzheimer's disease, membrane protein-rna complex, membrane protein/rna
• Biological source: Bos taurus (Bovine)
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor (By similarity): P10279
• Total number of polymer chains: 4
• Total formula weight: 10842.15

Authors

Hayashi, T.,Oshima, H.,Mashima, T.,Nagata, T.,Katahira, M.,Kinoshita, M. (deposition date: 2013-12-24, release date: 2014-05-21, Last modification date: 2023-06-14)

• Primary citation: Hayashi, T.,Oshima, H.,Mashima, T.,Nagata, T.,Katahira, M.,Kinoshita, M.; Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition.; Nucleic Acids Res., 42:6861-6875, 2014; PubMed: 24803670; DOI: 10.1093/nar/gku382

Experimental method

SOLUTION NMR